Sodium-ionophore-III-ETH2120-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESodium ionophore IIICat. No.: HY-101109CAS No.: 81686-22-8Synonyms: ETH2120分式: CHNO分量: 552.79作靶点: Sodium Channel作通路: Membrane Transporter/Ion Channel储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验

2、 DMSO : 1 mg/mL (1.81 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.8090 mL 9.0450 mL 18.0901 mL5 mM - - -10 mM - - -请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该

3、溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： corn oilSolubility: 2 mg/mL (3.62 mM); Suspended solution; Need ultrasonicBIOLOGICAL ACTIVITY1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE物活性 Sodium ionophore III (ETH2120)适于测定液、浆、清中的钠活性的Na+载体。体外研究 Preincubation of the cells with the Na+ ionophore sodium ionophore I

4、II not only stimulated caffeate reduction,but completely abolished ATP synthesis. Addition of sodium ionophore III to cells in the steady state of caffeatereduction immediately dissipated the intracellular ATP level 1. Lactate-sulfate grown cells are insensitive tothe Na+ ionophore, ETH2120 2. Sodiu

5、m ionophore III ligand is a very effective receptor for the Eu3+ andAm3+ cations and can be considered as a potential extraction agent for nuclear iste treatment 3.REFERENCES1. Imkamp F, et al. Chemiosmotic energy conservation with Na(+) as the coupling ion during hydrogen-dependent caffeate reducti

6、on byAcetobacterium woodii. J Bacteriol. 2002 Apr;184(7):1947-51.2. Wang L, et al. The role of Rnf in ion gradient formation in Desulfovibrio alaskensis. PeerJ. 2016 Apr 14;4:e1919.3. Makrlk, E, et al. Sodium Ionophore III as Very Effective Receptor for Trivalent Europium and Americium.J Solution Chem (2016) 45:463.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 4