Meropenem-trihydrate-SM-7338-trihydrate-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEMeropenem (trihydrate)Cat. No.: HY-13678ACAS No.: 119478-56-7Synonyms: SM 7338 trihydrate分式: CHNOS分量: 437.51作靶点: Bacterial作通路: Anti-infection储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO :

2、100 mg/mL (228.57 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.2857 mL 11.4283 mL 22.8566 mL5 mM 0.4571 mL 2.2857 mL 4.5713 mL10 mM 0.2286 mL 1.1428 mL 2.2857 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作

3、液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (5.71 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (5.71 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oil1/2 Ma

4、ster of Small Molecules 您边的抑制剂师www.MedChemESolubility: 2.5 mg/mL (5.71 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Meropenem trihydrate (SM 7338 trihydrate)碳 霉烯抗素，具有谱 antibacterial 活性的。户使本产品发表的科研献 Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00414-18. Int J Antimicrob Agents. 2018 Aug;52(2):2

5、69-271.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Slaney, L., et al., In-vitro activity of meropenem against Neisseria gonorrhoeae, Haemophilus influenzae and H. ducreyi from Canadaand Kenya. J Antimicrob Chemother, 1989. 24 Suppl A: p. 183-6.2. Yang, Y.J. and D.M. Livermo

6、re, Interactions of meropenem with class I chromosomal beta-lactamases. J Antimicrob Chemother, 1989.24 Suppl A: p. 207-17.3. Makino, J., et al., Pharmacokinetic study of penetration of meropenem into pleural effusion in patients with pleurisy. Jpn J Antibiot,2002. 55(1): p. 77-88.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400