Imiquimod-R-837-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEImiquimodCat. No.: HY-B0180CAS No.: 99011-02-6Synonyms: R 837分式: CHN分量: 240.3作靶点: Toll-like Receptor (TLR); Autophagy作通路: Immunology/Inflammation; Autophagy储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解

2、性数据体外实验 DMSO : 2.5 mg/mL (10.40 mM; Need ultrasonic and warming)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 4.1615 mL 20.8073 mL 41.6146 mL5 mM 0.8323 mL 4.1615 mL 8.3229 mL10 mM 0.4161 mL 2.0807 mL 4.1615 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Imiquimod (R 837)种

3、免疫反应调节剂，作为 toll-like receptor 7 的激动剂起作。IC50 & Target toll-like receptor 7 1体内研究In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activatingmacrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B1/2 Master o

4、f Small Molecules 您边的抑制剂师www.MedChemElymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release ofcytokines, including interferon-a (IFN-), interleukin (IL)-6, and tumour necrosis factor (TNF)- 1.户使本产品发表的科研献 Nat Commun. 2016 May 25;7:11724. Biomaterials. 2019 Jan.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Bilu D, et al. Imiquimod: modes of action. Br J Dermatol. 2003 Nov;149 Suppl 66:5-8.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-589559