1-Naphthyl-PP1-hydrochloride-1-NA-PP-1-hydrochloride-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE1-Naphthyl PP1 hydrochlorideCat. No.: HY-13941BCAS No.: 956025-47-1Synonyms: 1-NA-PP 1 hydrochloride分式: CHClN分量: 353.85作靶点: Src作通路: Protein Tyrosine Kinase/RTK储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 mont

2、h溶解性数据体外实验 DMSO : 73 mg/mL (206.30 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.8261 mL 14.1303 mL 28.2606 mL5 mM 0.5652 mL 2.8261 mL 5.6521 mL10 mM 0.2826 mL 1.4130 mL 2.8261 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 1-Na

3、phthyl PP1 hydrochloride是src家族抑制剂，对v-Src，c-Fyn，c-Abl，CDK2和CAMK II的IC50分别为1.0，0.6，0.6，18和22 M。户使本产品发表的科研献1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE Plant J. 2019 Mar;97(5):970-983.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Tandon M, et al. New pyrazolopyrimidine inhi

4、bitors of protein kinase d as potent anticancer agents for prostate cancer cells. PLoS One.2013 Sep 23;8(9):e75601.2. Bishop AC, et al. A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature. 2000 Sep 21;407(6802):395-401.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 021