时间常数实用学习教案

1、时间常数时间常数(sh jin chn sh)实用实用第一页，共22页。第1页/共22页第二页，共22页。第2页/共22页第三页，共22页。第3页/共22页第四页，共22页。第4页/共22页第五页，共22页。RC第5页/共22页第六页，共22页。第6页/共22页第七页，共22页。第7页/共22页第八页，共22页。PEFREELV吸气吸气(x q)呼气呼气PIFRVT第8页/共22页第九页，共22页。Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to measure total expiratory time constant

2、 based on the passive expiratory flow-volume curve. Critical Care Med 1995; 23(6):1117-1122流量(liling)(L/min)容积(rngj)(L)0VtPEFR第9页/共22页第十页，共22页。Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to measure total expiratory time constant based on the passive expiratory flow-volume curve. Critic

3、al Care Med 1995; 23(6):1117-1122流量(liling)(L/min)容积(rngj)(L)0VtPEFRTauE = Vt / PEFR第10页/共22页第十一页，共22页。第11页/共22页第十二页，共22页。第12页/共22页第十三页，共22页。Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to measure total expiratory time constant based on the passive expiratory flow-volume curve. Critical

4、 Care Med 1995; 23(6):1117-1122模拟(mn)肺y = 0.975x + 0.169r2 = 0.974动物(dngw)试验(犬)y = 1.033x + 0.038r2 = 0.969第13页/共22页第十四页，共22页。Brunner JX, Laubscher TP, Banner MJ, et al. Simple method to measure total expiratory time constant based on the passive expiratory flow-volume curve. Critical Care Med 1995;

5、 23(6):1117-1122第14页/共22页第十五页，共22页。Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618第15页/共22页第十六页，共22页。Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in

6、mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618RCfv100 = Vt / (V100, exp Vend, ex)RCfv75 = 0.75 x Vt / (V75, exp Vend, ex)RCfv50 = 0.50 x Vt / (V50, exp Vend, ex)RCfv25 = 0.25 x Vt / (V25, exp Vend, ex)第16页/共22页第十七页，共22页。Lourens MS, van den Berg B, Aert

7、s JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618重度COPD中度COPD其他病因RCint2.88 1.611.02 0.400.65 0.28RCfvp0.75 0.200.70 0.190.60 0.10RCfv1000.85 0.180.79 0.220.63 0.12RCfv752.84 1.531.05 0.320.72 0.18RCfv503.42 1.61

8、 1.25 0.440.84 0.39RCfv254.20 1.991.47 0.571.06 0.63第17页/共22页第十八页，共22页。Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without COPD. Intensive Care Med 2000; 26: 1612-1618第18页/共22页第十九页，共22页。Lourens MS, van den Berg B, Aerts JGJV, et al. Expiratory time constants in mechanically ventilated patients with and without CO