小儿睡眠呼吸暂停

1、Nelson 儿科学，17版，2007；99Nelson 儿科学，17版，2007；99Nelson 儿科学，17版，2007；99 WATERS K A, Am J Med Genet, 1995, 59(4): 460-466.Hsueh-yu L, Chang Gung Med J,2009;32:24757AMERICAN THORACIC SOCIETY. Am J Respir Crit Care Med,1996, 153(2): 866-878. AMERICAN THORACIC SOCIETY. Am J Respir Crit Care Med,1996, 153(2):

2、 866-878.OSAS in children is a disorder of breathing during sleepcharacterized by prolonged partial upper airway obstruction and/or intermittent complete obstruction(obstructive apnea)that disrupts normal ventilation during sleep and normal sleep patterns. It is associated with symptoms including ha

3、bitual (nightly) snoring, sleep difficulties, and/or daytime neurobehavioral problems. Complications may include growth abnormalities, neurologic disorders, and cor pulmonale, especially in severe cases. Various risk factors have beenidentified and are defined.Carolyn E I-L，AJRCCM，2007；175：436441Osc

4、ar S C，Proc Am Thorac Soc, 2008；5：274282Oscar S C，Proc Am Thorac Soc, 2008；5：274282Kahn A，Sleep,1993;16:409413Crouzon syndromeOscar S C，Proc Am Thorac Soc, 2008；5：274282Oscar S C，Proc Am Thorac Soc, 2008；5：274282蒙逖航,医学综述,2008;14(20):31413143OSA引起心血管事件的细胞学机制Athanasios G，Chest，2008；134：324331A, adenoi

5、d; N, nasopharyngeal measurement; P,pharyngeal measurement; T, tonsil. T/P 0.479提示中重度OSA。A/N 0.74以上A M Li, Arch Dis Child 2002;87:156159 Liner LH, Curr Opin Pediatr,2006, 18(3): 272-276.S L Verhulst，Arch Dis Child 2006;91:233237Marcus CL, Pediatr Pulmonol,1992;13:1621Biban P,Pediatrics,1993;92:46146

6、3Brouillette R, J Pediatr. 1984;105:1014William WH，Pediatrics Current diagnosis & Treatment，19th ed，2009；467McColley S，Arch Otolaryngol Head Neck Surg，1992；118（9）：940943Goldberg S，Pediatr Pulmonol，2005；40（3）：205210Rosen GM，Pediatrics，1994；93（5）：784788Gorur K,Int J Pediatr Otorhinolaryngol,2001,5

7、9(1):41-46.Basha S,Laryngoscope,2005,115(6):1101-1103.Mitchell Int JPediatrOtorhinolaryngol,2004,68 (11):1375-1379.张亚梅,王桂香.中国全科医学, 2007, 10(2): 102-104.年幼儿因颅面生长快年幼儿因颅面生长快, ,应每应每6 6月评价月评价1 1次次Massa F，Arch Dis Child，2002；87：438443FT 失败例ST 成功例不同年龄段nCPAP的成功率Massa F，Arch Dis Child，2002；87：438443Craig AH，Neuropsychi Dis Treat，2006；2（3）：30926Craig AH，Neuropsychi Dis Treat，2006；2（3）：30926 Hoban TF,Neurologist,2005, 11(6):