人类所有持家基因列表

1、所有的看家基因的列表，大家在设计引物时，可以直接采用这些基因的序列，本表来自于Trends in Gentics上一篇文献，内容全面，所有的看家基因均标注了基因银行号（Genbank），可以直接到pubmed中查询得出。引物设计可以推荐用primer 5，也可以直接与我们联系设计，有关事宜，请点击：ng/200506/130599.html （引物设计与合成服务）。List of housekeeping genes derived from the article "Human Housekeeping genes are compact," published

2、 in Trends in Genetics 19, 362-365 (2003).Each gene name/description is followed by its geometric average expression level according to the data published by Su et al. Genes designated by asterisk are in popular use as reference in real-time PCR.  *NM_001101Homo sapiens actin, beta (ACTB), mRNA

3、6988*NM_000034Homo sapiens aldolase A,fructose-bisphosphate (ALDOA), mRNA3425*NM_002046Homo sapiens glyceraldehyde-3-phosphate dehydrogenase (GAPD), mRNA828*NM_000291Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA2727*NM_005566Homo sapiens lactate dehydrogenase A (LDHA), mRNA2105*NM_002954Homo s

4、apiens ribosomal protein S27a (RPS27A), mRNA4156*NM_000981Homo sapiens ribosomal protein L19 (RPL19), mRNA6997*NM_000975Homo sapiens ribosomal protein L11 (RPL11), mRNA6060*NM_007363Homo sapiens non-POU domain containing, octamer-binding (NONO), mRNA1708*NM_004309Homo sapiens Rho GDP dissociation in

5、hibitor (GDI) alpha (ARHGDIA), mRNA1358*NM_000994Homo sapiens ribosomal protein L32 (RPL32), mRNA9523*NM_022551Homo sapiens ribosomal protein S18 (RPS18), mRNA11261*NM_007355Homo sapiens heat shock 90kDa protein 1, beta (HSPCB), mRNA4119NM_004515Homo sapiens interleukin enhancer binding factor 2, 45

6、kDa (ILF2), mRNA1000NM_004651Homo sapiens ubiquitin specific protease 11 (USP11), mRNA1950NM_004888Homo sapiens ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 1(ATP6V1G1), mRNA928NM_003334Homo sapiens ubiquitin-activating enzyme E1 (A1S9T and BN75 temperaturesensitivity complementing

7、) (UBE1), transcript variant 1, mRNA1351NM_001320Homo sapiens casein kinase 2, beta polypeptide (CSNK2B), mRNA1233NM_003915Homo sapiens copine I (CPNE1), transcript variant 3, mRNA698NM_001250Homo sapiens tumor necrosis factor receptor superfamily, member 5 (TNFRSF5),transcript variant 1, mRNA524NM_

8、001904Homo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), mRNA1165NM_003753Homo sapiens eukaryotic translation initiation factor 3, subunit 7 zeta,66/67kDa (EIF3S7), mRNA1363NM_004541Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa(NDUFA1), nuclear g

9、ene encoding mitochondrial protein, mRNA2307NM_001654Homo sapiens v-raf murine sarcoma 3611 viral oncogene homolog 1 (ARAF1), mRNA846NM_002967Homo sapiens scaffold attachment factor B (SAFB), mRNA545NM_001183Homo sapiens ATPase, H+ transporting, lysosomal interacting protein 1 (ATP6IP1),mRNA1089NM_0

10、03526Homo sapiens H2B histone family, member L (H2BFL), mRNA2232NM_004718Homo sapiens cytochrome c oxidase subunit VIIa polypeptide 2 like (COX7A2L),nuclear gene encoding mitochondrial protein, mRNA1013NM_004436Homo sapiens endosulfine alpha (ENSA), mRNA659NM_001207Homo sapiens basic transcription f

11、actor 3 (BTF3), mRNA3348NM_004907Homo sapiens immediate early protein (ETR101), mRNA1249NM_004889Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f,isoform 2 (ATP5J2), mRNA1513NM_003769Homo sapiens splicing factor, arginine/serine-rich 9 (SFRS9), mRNA1207NM_003910Homo sa

12、piens maternal G10 transcript (G10), mRNA696NM_000100Homo sapiens cystatin B (stefin B) (CSTB), mRNA1422NM_004785Homo sapiens solute carrier family 9 (sodium/hydrogen exchanger), isoform 3regulatory factor 2 (SLC9A3R2), mRNA455NM_001120Homo sapiens tetracycline transporter-like protein (TETRAN), mRN

13、A935NM_000182Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme Athiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit(HADHA), mRNA609NM_003377Homo sapiens vascular endothelial growth factor B (VEGFB), mRNA649NM_003576Homo sapiens serine/threonine kinase 24 (S

14、TE20 homolog, yeast) (STK24), mRNA769NM_000918Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormonebinding protein p55) (P4HB), mRNA2719NM_004584Homo sapiens RAD9 homolog (S. pombe) (RAD9), mRNA860NM_0049

15、52Homo sapiens ephrin-A3 (EFNA3), mRNA505NM_004308Homo sapiens Rho GTPase activating protein 1 (ARHGAP1), mRNA893NM_003190Homo sapiens TAP binding protein (tapasin) (TAPBP), mRNA1213NM_004640Homo sapiens HLA-B associated transcript 1 (BAT1), transcript variant 1, mRNA1022NM_001064Homo sapiens transk

16、etolase (Wernicke-Korsakoff syndrome) (TKT), mRNA1139NM_002117Homo sapiens major histocompatibility complex, class I, C (HLA-C), mRNA4696NM_004161Homo sapiens RAB1A, member RAS oncogene family (RAB1A), mRNA2163NM_003339Homo sapiens ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)(UBE2D2),

17、mRNA514NM_003969Homo sapiens ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) (UBE2M),mRNA1197NM_000516Homo sapiens GNAS complex locus (GNAS), transcript variant 1, mRNA4358NM_002819Homo sapiens polypyrimidine tract binding protein 1 (PTBP1), transcript variant1, mRNA1138NM_001001Homo sapiens

18、 ribosomal protein L36a-like (RPL36AL), mRNA1740NM_004649Homo sapiens chromosome 21 open reading frame 33 (C21orf33), mRNA585NM_000175Homo sapiens glucose phosphate isomerase (GPI), mRNA1633NM_001867Homo sapiens cytochrome c oxidase subunit VIIc (COX7C), nuclear gene encodingmitochondrial protein, m

19、RNA3004NM_001967Homo sapiens eukaryotic translation initiation factor 4A, isoform 2 (EIF4A2),mRNA2935NM_001863Homo sapiens cytochrome c oxidase subunit VIb (COX6B), nuclear gene encodingmitochondrial protein, mRNA1719NM_001997Homo sapiens Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquito

20、uslyexpressed (fox derived); ribosomal protein S30 (FAU), mRNA3898NM_002088Homo sapiens glutamate receptor, ionotropic, kainate 5 (GRIK5), mRNA535NM_001862Homo sapiens cytochrome c oxidase subunit Vb (COX5B), nuclear gene encodingmitochondrial protein, mRNA1087NM_004255Homo sapiens cytochrome c oxid

21、ase subunit Va (COX5A), nuclear gene encodingmitochondrial protein, mRNA853NM_001788Homo sapiens CDC10 cell division cycle 10 homolog (S. cerevisiae) (CDC10), mRNA1340NM_004781Homo sapiens vesicle-associated membrane protein 3 (cellubrevin) (VAMP3), mRNA684NM_003801Homo sapiens GPAA1P anchor attachm

22、ent protein 1 homolog (yeast) (GPAA1), mRNA776NM_004643Homo sapiens poly(A) binding protein, nuclear 1 (PABPN1), mRNA502NM_001537Homo sapiens heat shock factor binding protein 1 (HSBP1), mRNA874NM_003680Homo sapiens tyrosyl-tRNA synthetase (YARS), mRNA535NM_003345Homo sapiens ubiquitin-conjugating e

23、nzyme E2I (UBC9 homolog, yeast) (UBE2I),mRNA1283NM_002568Homo sapiens poly(A) binding protein, cytoplasmic 1 (PABPC1), mRNA3199NM_001487Homo sapiens GCN5 general control of amino-acid synthesis 5-like 1 (yeast)(GCN5L1), mRNA313NM_001861Homo sapiens cytochrome c oxidase subunit IV isoform 1 (COX4I1),

24、 nuclear geneencoding mitochondrial protein, mRNA2738NM_004890Homo sapiens sperm associated antigen 7 (SPAG7), mRNA618NM_002812Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (PSMD8),mRNA942NM_004926Homo sapiens zinc finger protein 36, C3H type-like 1 (ZFP36L1), mRNA1168NM_00

25、2539Homo sapiens ornithine decarboxylase 1 (ODC1), mRNA1361NM_000979Homo sapiens ribosomal protein L18 (RPL18), mRNA4417NM_000977Homo sapiens ribosomal protein L13 (RPL13), transcript variant 1, mRNA6407NM_001015Homo sapiens ribosomal protein S11 (RPS11), mRNA7614NM_001760Homo sapiens cyclin D3 (CCN

26、D3), mRNA676NM_003973Homo sapiens ribosomal protein L14 (RPL14), mRNA3135NM_002815Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 11(PSMD11), mRNA536NM_000367Homo sapiens thiopurine S-methyltransferase (TPMT), mRNA1574NM_000973Homo sapiens ribosomal protein L8 (RPL8), transcrip

27、t variant 1, mRNA8138NM_004689Homo sapiens metastasis associated 1 (MTA1), mRNA506NM_001848Homo sapiens collagen, type VI, alpha 1 (COL6A1), mRNA757NM_004068Homo sapiens adaptor-related protein complex 2, mu 1 subunit (AP2M1), mRNA2188NM_001687Homo sapiens ATP synthase, H+ transporting, mitochondria

28、l F1 complex, deltasubunit (ATP5D), mRNA1167NM_004197Homo sapiens serine/threonine kinase 19 (STK19), transcript variant 1, mRNA574NM_001028Homo sapiens ribosomal protein S25 (RPS25), mRNA4683NM_001022Homo sapiens ribosomal protein S19 (RPS19), mRNA6683NM_004759Homo sapiens mitogen-activated protein

29、 kinase-activated protein kinase 2(MAPKAPK2), transcript variant 1, mRNA641NM_001623Homo sapiens allograft inflammatory factor 1 (AIF1), transcript variant 3, mRNA497NM_004894Homo sapiens chromosome 14 open reading frame 2 (C14orf2), mRNA704NM_002375Homo sapiens microtubule-associated protein 4 (MAP

30、4), transcript variant 1, mRNA717NM_001013Homo sapiens ribosomal protein S9 (RPS9), mRNA6868NM_003779Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3(B4GALT3), mRNA565NM_001296Homo sapiens chemokine binding protein 2 (CCBP2), mRNA394NM_001009Homo sapiens ribosomal prote

31、in S5 (RPS5), mRNA6739NM_003021Homo sapiens small glutamine-rich tetratricopeptide repeat (TPR)-containing(SGT), mRNA488NM_004285Homo sapiens hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) (H6PD),mRNA646NM_004142Homo sapiens matrix metalloproteinase-like 1 (MMPL1), mRNA695NM_001950Homo s

32、apiens E2F transcription factor 4, p107/p130-binding (E2F4), mRNA956NM_003815Homo sapiens a disintegrin and metalloproteinase domain 15 (metargidin)(ADAM15), mRNA771NM_001119Homo sapiens adducin 1 (alpha) (ADD1), transcript variant 1, mRNA1356NM_001111Homo sapiens adenosine deaminase, RNA-specific (

33、ADAR), transcript variantADAR-a, mRNA1036NM_003466Homo sapiens paired box gene 8 (PAX8), transcript variant PAX8A, mRNA901NM_001155Homo sapiens annexin A6 (ANXA6), transcript variant 1, mRNA718NM_003465Homo sapiens chitinase 1 (chitotriosidase) (CHIT1), mRNA561NM_003186Homo sapiens transgelin (TAGLN

34、), mRNA1209NM_000802Homo sapiens folate receptor 1 (adult) (FOLR1), transcript variant 2, mRNA514NM_004924Homo sapiens actinin, alpha 4 (ACTN4), mRNA1187NM_002931Homo sapiens ring finger protein 1 (RING1), mRNA576NM_000020Homo sapiens activin A receptor type II-like 1 (ACVRL1), mRNA849NM_001785Homo

35、sapiens cytidine deaminase (CDA), mRNA391NM_004339Homo sapiens pituitary tumor-transforming 1 interacting protein (PTTG1IP), mRNA1200NM_003860Homo sapiens Breakpoint cluster region protein, uterine leiomyoma, 1; barrier toautointegration factor (BCRP1), mRNA1303NM_000214Homo sapiens jagged 1 (Alagil

36、le syndrome) (JAG1), mRNA536NM_002167Homo sapiens inhibitor of DNA binding 3, dominant negative helix-loop-helixprotein (ID3), mRNA1192NM_001664Homo sapiens ras homolog gene family, member A (ARHA), mRNA4050NM_003166Homo sapiens sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3(SUL

37、T1A3), mRNA461NM_001746Homo sapiens calnexin (CANX), mRNA1923NM_001662Homo sapiens ADP-ribosylation factor 5 (ARF5), mRNA724NM_001660Homo sapiens ADP-ribosylation factor 4 (ARF4), mRNA1014NM_001658Homo sapiens ADP-ribosylation factor 1 (ARF1), mRNA2195NM_003313Homo sapiens tissue specific transplant

38、ation antigen P35B (TSTA3), mRNA440NM_001494Homo sapiens GDP dissociation inhibitor 2 (GDI2), mRNA1352NM_003145Homo sapiens signal sequence receptor, beta (translocon-associated protein beta)(SSR2), mRNA1265NM_001619Homo sapiens adrenergic, beta, receptor kinase 1 (ADRBK1), mRNA695NM_001420Homo sapi

39、ens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Huantigen C) (ELAVL3), mRNA1070NM_004930Homo sapiens capping protein (actin filament) muscle Z-line, beta (CAPZB), mRNA1183NM_004596Homo sapiens small nuclear ribonucleoprotein polypeptide A (SNRPA), mRNA734NM_004168Homo sapiens succin

40、ate dehydrogenase complex, subunit A, flavoprotein (Fp)(SDHA), nuclear gene encoding mitochondrial protein, mRNA1106NM_004156Homo sapiens protein phosphatase 2 (formerly 2A), catalytic subunit, betaisoform (PPP2CB), mRNA1195NM_004910Homo sapiens phosphatidylinositol transfer protein, membrane-associ

41、ated(PITPNM), mRNA869NM_004517Homo sapiens integrin-linked kinase (ILK), mRNA654NM_004494Homo sapiens hepatoma-derived growth factor (high-mobility group protein 1-like)(HDGF), mRNA1385NM_004121Homo sapiens gamma-glutamyltransferase-like activity 1 (GGTLA1), mRNA412NM_004404Homo sapiens neural precu

42、rsor cell expressed, developmentally down-regulated 5(NEDD5), mRNA1571NM_004394Homo sapiens death-associated protein (DAP), mRNA623NM_004383Homo sapiens c-src tyrosine kinase (CSK), mRNA899NM_004074Homo sapiens cytochrome c oxidase subunit VIII (COX8), nuclear gene encodingmitochondrial protein, mRN

43、A3188NM_004039Homo sapiens annexin A2 (ANXA2), mRNA2417NM_001053Homo sapiens somatostatin receptor 5 (SSTR5), mRNA423NM_001328Homo sapiens C-terminal binding protein 1 (CTBP1), mRNA798NM_001273Homo sapiens chromodomain helicase DNA binding protein 4 (CHD4), mRNA775NM_003430Homo sapiens zinc finger p

44、rotein 91 (HPF7, HTF10) (ZNF91), mRNA716NM_003314Homo sapiens tetratricopeptide repeat domain 1 (TTC1), mRNA651NM_003217Homo sapiens testis enhanced gene transcript (TEGT), mRNA1766NM_003132Homo sapiens spermidine synthase (SRM), mRNA1093NM_000199Homo sapiens N-sulfoglucosamine sulfohydrolase (sulfa

45、midase) (SGSH), mRNA565NM_002818Homo sapiens proteasome (prosome, macropain) activator subunit 2 (PA28 beta)(PSME2), mRNA697NM_002733Homo sapiens protein kinase, AMP-activated, gamma 1 non-catalytic subunit(PRKAG1), mRNA497NM_002631Homo sapiens phosphogluconate dehydrogenase (PGD), mRNA1009NM_002574

46、Homo sapiens peroxiredoxin 1 (PRDX1), mRNA2241NM_002512Homo sapiens non-metastatic cells 2, protein (NM23B) expressed in (NME2),nuclear gene encoding mitochondrial protein, mRNA2553NM_002455Homo sapiens metaxin 1 (MTX1), mRNA845NM_002444Homo sapiens moesin (MSN), mRNA1798NM_000529Homo sapiens melano

47、cortin 2 receptor (adrenocorticotropic hormone) (MC2R), mRNA420NM_003573Homo sapiens latent transforming growth factor beta binding protein 4 (LTBP4),mRNA740NM_002315Homo sapiens LIM domain only 1 (rhombotin 1) (LMO1), mRNA469NM_000884Homo sapiens IMP (inosine monophosphate) dehydrogenase 2 (IMPDH2)

48、, mRNA1288NM_003641Homo sapiens interferon induced transmembrane protein 1 (9-27) (IFITM1), mRNA4898NM_000841Homo sapiens glutamate receptor, metabotropic 4 (GRM4), mRNA1369NM_002070Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibitingactivity polypeptide 2 (GNAI2), mRNA1877N

49、M_001493Homo sapiens GDP dissociation inhibitor 1 (GDI1), mRNA1387NM_002048Homo sapiens growth arrest-specific 1 (GAS1), mRNA940NM_002032Homo sapiens ferritin, heavy polypeptide 1 (FTH1), mRNA2616NM_001418Homo sapiens eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2), mRNA3646NM_001350Hom

50、o sapiens death-associated protein 6 (DAXX), mRNA510NM_001843Homo sapiens contactin 1 (CNTN1), mRNA535NM_001728Homo sapiens basigin (BSG), mRNA1508NM_001667Homo sapiens ADP-ribosylation factor-like 2 (ARL2), mRNA965NM_001659Homo sapiens ADP-ribosylation factor 3 (ARF3), mRNA1327NM_003746Homo sapiens

51、 dynein, cytoplasmic, light polypeptide 1 (DNCL1), mRNA2758NM_002127Homo sapiens HLA-G histocompatibility antigen, class I, G (HLA-G), mRNA1090NM_004712Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS),mRNA505NM_003475Homo sapiens chromosome 11 open reading frame 13 (C1

52、1orf13), mRNA413NM_004046Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, alphasubunit, isoform 1, cardiac muscle (ATP5A1), mRNA1348NM_001894Homo sapiens casein kinase 1, epsilon (CSNK1E), transcript variant 2, mRNA613NM_003795Homo sapiens sorting nexin 3 (SNX3), transcript vari

53、ant 1, mRNA1426NM_001909Homo sapiens cathepsin D (lysosomal aspartyl protease) (CTSD), mRNA1512NM_002792Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 7 (PSMA7),transcript variant 1, mRNA728NM_002799Homo sapiens proteasome (prosome, macropain) subunit, beta type, 7 (PSMB7), mRNA54

54、5NM_002300Homo sapiens lactate dehydrogenase B (LDHB), mRNA4144NM_004176Homo sapiens sterol regulatory element binding transcription factor 1 (SREBF1),mRNA632NM_002796Homo sapiens proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4), mRNA1229NM_002794Homo sapiens proteasome (prosome, macrop

55、ain) subunit, beta type, 2 (PSMB2), mRNA1304NM_002793Homo sapiens proteasome (prosome, macropain) subunit, beta type, 1 (PSMB1), mRNA2084NM_002473Homo sapiens myosin, heavy polypeptide 9, non-muscle (MYH9), mRNA1381NM_001810Homo sapiens centromere protein B, 80kDa (CENPB), mRNA532NM_002624Homo sapie

56、ns prefoldin 5 (PFDN5), transcript variant 1, mRNA1718NM_004710Homo sapiens synaptogyrin 2 (SYNGR2), mRNA1414NM_001127Homo sapiens adaptor-related protein complex 1, beta 1 subunit (AP1B1),transcript variant 1, mRNA873NM_002107Homo sapiens H3 histone, family 3A (H3F3A), mRNA9328NM_003899Homo sapiens

57、 Rho guanine nucleotide exchange factor (GEF) 7 (ARHGEF7),transcript variant 1, mRNA558NM_003406Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activationprotein, zeta polypeptide (YWHAZ), transcript variant 1, mRNA2008NM_002419Homo sapiens mitogen-activated protein kinase kinase kinase 11 (MAP3K11), mRNA535NM_001130Homo sapiens amin