Solasonine-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemESolasonine(Standard)Cat.No.:HY-N0070RCASNo.:19121-58-5分子式:C₄₅H₇₃NO₁₆分子量:884.06作用靶点:Ferroptosis;Ferroptosis;GlutathionePeroxidase;GlutathionePeroxidase;ReactiveOxygenSpecies;ReactiveOxygenSpecies作用通路:Apoptosis;MetabolicEnzyme/Protease;Immunology/Inflammation;NF-κB储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性Solasonine(Standard)是Solasonine的分析标准品。本产品用于研究及分析应用。Solasonine是一种可从茄属植物中提取的铁死亡(ferroptosis)诱导剂，具有抗感染、抗癌、促进神经发生等作用。Solasonine通过抑制GPX4来诱导谷胱甘肽氧化还原系统的破坏，促进肝癌细胞铁死亡，可用于癌症研究[1][2]。REFERENCESDingX,etal.Purification,antitumoractivityinvitroofsteroidalglycoalkaloidsfromblacknightshade(SolanumnigrumL.).FoodChem.2013Nov15;141(2):1181-6.JinM,etal.Solasoninepromotesferroptosisofhepatomacarcinomacellsviaglutathioneperoxidase4-induceddestructionoftheglutathioneredoxsystem.BiomedPharmacother.2020Sep;129:110282.DingX,etal.Purification,antitumoractivityinvitroofsteroidalglycoalkaloidsfromblacknightshade(SolanumnigrumL.).FoodChem.2013Nov15;141(2):1181-6.JinM,etal.Solasoninepromotesferroptosisofhepatomacarcinomacellsviaglutathioneperoxidase4-induceddestructionoftheglutathioneredoxsystem.BiomedPharmacother.2020Sep;129:110282.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax: