Naringenin-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemENaringenin(Standard)Cat.No.:HY-N0100RCASNo.:480-41-1分子式:C₁₅H₁₂O₅分子量:272.25作用靶点:Denguevirus;PPAR;ReactiveOxygenSpecies;InfluenzaVirus;EndogenousMetabolite作用通路:Anti-infection;CellCycle/DNADamage;MetabolicEnzyme/Protease;VitaminDRelated/NuclearReceptor;Immunology/Inflammation;NF-κB储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 Naringenin(Standard)是Naringenin的分析标准品。本产品用于研究及分析应用。Naringenin是柑橘中主要的黄烷酮;显示出强烈的抗炎和抗氧化活性。Naringenin具有抗登革热病毒(DENV)活性。REFERENCESArulD,etal.Naringenin(citrusflavonone)inducesgrowthinhibition,cellcyclearrestandapoptosisinhumanhepatocellularcarcinomacells.PatholOncolRes.2013Oct;19(4):763-70.AhamadMS,etal.InductionofapoptosisandantiproliferativeactivityofnaringenininhumanepidermoidcarcinomacellthroughROSgenerationandcellcyclearrest.PLoSOne.2014Oct16;9(10):e110003.ChoKW,etal.Dietarynaringeninincreaseshepaticperoxisomeproliferators-activatedreceptorαproteinexpressionanddecreasesplasmatriglycerideandadiposityinrats.EurJNutr.2011Mar;50(2):81-8.MulvihillEE,etal.Naringeninpreventsdyslipidemia,apolipoproteinBoverproduction,andhyperinsulinemiainLDLreceptor-nullmicewithdiet-inducedinsulinresistance.Diabetes.2009Oct;58(10):2198-210.ChenS,etal.NaringenininhibitsTNF-αinducedVSMCproliferationandmigrationviainductionofHO-1.FoodChemToxicol.2012Sep;50(9):3025-31.FrabasileS,etal.Thecitrusflavanonenaringeninimpairsdenguevirusreplicationinhumancells.SciRep.2017Feb3;7:41864.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;0