Chicoric-acid-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemEChicoricacid(Standard)Cat.No.:HY-N0457RCASNo.:6537-80-0分子式:C₂₂H₁₈O₁₂分子量:474.37作用靶点:ReactiveOxygenSpecies;ReactiveOxygenSpecies;Apoptosis;Apoptosis作用通路:Immunology/Inflammation;MetabolicEnzyme/Protease;NF-κB;Apoptosis储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 Chicoricacid(Standard)是Chicoricacid的分析标准品。本产品用于研究及分析应用。Chicoricacid(Cichoricacid)是一种口服有效的二咖啡基酒石酸，可以诱导活性氧(ROS)的产生。Chicoricacid抑制细胞活力，并通过ROS介导的PI3K/Akt和MAPK信号通路诱导3T3-L1前脂肪细胞中的线粒体依赖性细胞凋亡。Chicoricacid增加葡萄糖摄取，改善胰岛素抵抗，并减轻氨基葡萄糖诱导的炎症REFERENCESDiZhu,etal.CichoricAcidReversesInsulinResistanceandSuppressesInflammatoryResponsesintheGlucosamine-InducedHepG2Cells.JAgricFoodChem.2015Dec30;63(51):10903-13.DiZhu,etal.CichoricacidimprovedhyperglycaemiaandrestoredmuscleinjuryviaactivatingantioxidantresponseinMLD-STZ-induceddiabeticmice.FoodChemToxicol.2017Sep;107(PtA):138-149.HaifangXiao,etal.Chicoricacidinducesapoptosisin3T3-L1preadipocytesthroughROS-mediatedPI3K/AktandMAPKsignalingpathways.JAgricFoodChem.2013Feb20;61(7):1509-20.DiZhu,etal.CichoricAcidReversesInsulinResistanceandSuppressesInflammatoryResponsesintheGlucosamine-InducedHepG2Cells.JAgricFoodChem.2015Dec30;63(51):10903-13.DiZhu,etal.CichoricacidimprovedhyperglycaemiaandrestoredmuscleinjuryviaactivatingantioxidantresponseinMLD-STZ-induceddiabeticmice.FoodChemToxicol.2017Sep;107(PtA):138-149.HaifangXiao,etal.Chicoricacidinducesapoptosisin3T3-L1preadipocytesthroughROS-mediatedPI3K/AktandMAPKsignalingpathways.JAgricFoodChem.2013Feb20;61(7):1509-20.McePdfHeight1/1 MasterofBioactiveMolecules—您身边的抑制剂大师www.MedChemECaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-