beta-Mangostin-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemEbeta-Mangostin(Standard)Cat.No.:HY-N0941RCASNo.:20931-37-7分子式:C₂₅H₂₈O₆分子量:424.49作用靶点:Bacterial;Parasite;Apoptosis作用通路:Anti-infection;Apoptosis储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 beta-Mangostin(Standard)是beta-Mangostin的分析标准品。本产品用于研究及分析应用。beta-Mangostin(β-Mangostin)是存在Garciniamangostana中的一种氧杂蒽酮化合物，具有抗菌和抗疟疾活性。beta-Mangostin对结核分枝杆菌作用的MIC值为6.25μg/mL。beta-Mangostin具有体外抗疟活性，对恶性疟原虫作用的IC50值REFERENCESChien-FengHuang,etal.β-mangostinsuppresseshumanhepatocellularcarcinomacellinvasionthroughinhibitionofMMP-2andMMP-9expressionandactivatingtheERKandJNKpathways.EnvironToxicol.2017Nov;32(11):2360-2370.FatimaAbdelmutaalAhmedOmer,etal.Beta-mangostinfromCratoxylumarborescensactivatestheintrinsicapoptosispathwaythroughreactiveoxygenspecieswithdownregulationoftheHSP70geneintheHL60cellsassociatedwithaG0/G1cell-cyclearrest.TumourBiol.2017Nov;39(11):1010428317731451.KLikhitwitayawuid,etal.AntimalarialxanthonesfromGarciniacowa.PlantaMed.1998Feb;64(1):70-2.SunitSuksamrarn,etal.AntimycobacterialactivityofprenylatedxanthonesfromthefruitsofGarciniamangostana.ChemPharmBull(Tokyo).2003Jul;51(7):857-9.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax: