Citrinin-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemECitrinin(Standard)Cat.No.:HY-N6746RCASNo.:518-75-2分子式:C₁₃H₁₄O₅分子量:250.25作用靶点:Bacterial;Bacterial;Fungal;Fungal;EndogenousMetabolite;EndogenousMetabolite;Apoptosis作用通路:Anti-infection;MetabolicEnzyme/Protease;Apoptosis储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 Citrinin(Standard)是Citrinin的分析标准品。本产品用于研究及分析应用。Citrinin(NSC186)是一种引起食品污染的真菌毒素，具有不同的毒性作用。Citrinin是口服有效的抗癌剂。Citrinin对小鼠免疫系统具有多方面的调节作用，包括调节免疫细胞数量、诱导免疫细胞凋亡和自噬、改变toll样受体表达和细胞因子产生等。Citrinin可诱导氧化应激导致卵母细胞早期凋亡。低剂量Citrinin在大鼠皮层神经元中对谷氨酸诱导的兴奋性毒性具有神经保护作用。REFERENCESdeOliveiraFilhoJWG,etal,Acomprehensivereviewonbiologicalpropertiesofcitrinin.FoodChemToxicol.2017Dec;110:130-141.ČuligB,etal.PRESENCEOFCITRINININGRAINSANDITSPOSSIBLEHEALTHEFFECTS.AfrJTraditComplementAlternMed.2017Mar1;14(3):22-30deOliveiraFilhoJWG,etal,Acomprehensivereviewonbiologicalpropertiesofcitrinin.FoodChemToxicol.2017Dec;110:130-141.IslamMR,etal.Immunemodulatoryeffectsofthefoodbornecontaminantcitrinininmice.FoodChemToxicol.2012Oct;50(10):3537-47.deOliveiraFilhoJWG,etal.Citrininagainstbreastcancer:Acytogenotoxicologicalstudy.PhytotherRes.2021Jan;35(1):504-516.NakajimaY,etal.Lowdosesofthemycotoxincitrininprotectcorticalneuronsagainstglutamate-inducedexcitotoxicity.JToxicolSci.2016Apr;41(2):311-9.WuY,etal.Citrininexposureaffectsoocytematurationandembryodevelopmentbyinducingoxidativestress-mediatedapoptosis.Oncotarget.2017May23;8(21):34525-34533.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;02