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INDUSTRIES

&

MARKETSDiabetesintheMiddleEastandNorthAfricaregionCHAPTER

01GlobaloverviewPercentageofadultsworldwidewhostatedselectissueswerethebiggesthealthproblemsfacingpeopleintheircountryin2023Leadinghealthproblemsworldwide2023Percentageofrespondents0%5%10%15%20%25%30%35%40%45%50%Mentalhealth44%CancerStress40%30%Obesity25%Drugabuse22%Diabetes18%17%AlcoholabuseHeartdisease15%15%Coronavirus/COVID-19Smoking12%Dementia8%Sexuallytransmitteddiseases(STD)HospitalsuperbugsOther4%3%2%3Description:Asurveyofpeoplefrom31differentcountriesaroundtheworldfoundthatmentalhealthwasthebiggesthealthproblemrespondentssaidwasfacingtheircountryin2023.Otherhealthproblemsreportedbyrespondentsincludedcancer,stress,andobesity.ReadmoreNote(s):Worldwide;July21toAugust4,2023;23,274respondents;16-74years;31countriesSource(s):IpsosEstimatednumberofdiabeticsworldwidein2021,2030,and2045(inmillions)Diabeticsworldwide2021,2030,and2045900800700600783643537500400300200100020212030*2045*4Description:Thenumberofdiabeticsworldwidein2021was537million.Thatnumberisexpectedtogrowuntilatleasttheyear2045.Theprojectednumberofdiabeticsisexpectedtoreach783millionbythattime.Withanincreasednumberofdiabetics,theprevalenceofdiabetesisalsoprojectedtoincreasetoaround12percentby2045.ReadmoreNote(s):Worldwide;20-79yearsSource(s):InternationalDiabetesFederationDiabetesprevalencebyworldregionin2021and2045*Prevalenceofdiabetesworldwidebyregion2021and2045Age-adjustedprevalence204520210%5%10%15%20%25%20.4%MiddleEastandNorthAfricaNorthAmericaandCaribbeanSouth-EastAsia18.1%14.2%11.9%11.3%10%11.5%WesternPacific9.9%9.8%SouthandCentralAmericaEurope8.2%8.7%7%5.6%5.3%Africa5Description:Thisstatisticshowstheworldregions'ageadjusteddiabetesprevalenceamongadults(20-79years)in2021anda2045forecast.In2021,NorthAmericaandtheCaribbeanhada12percentdiabetesprevalence.

ReadmoreNote(s):Worldwide;20-79years;*Allfiguresareage-adjustedestimates/forecasts.ReadmoreSource(s):InternationalDiabetesFederationNumberofdeathsbeforetheageof60duetodiabetesworldwidein2021,byregion(inthousands)Numberofdiabetesdeathsworldwide2021,byregion800717.4700600500428.64003002001000306301.2199.9144.786.7WesternPacificMiddleEastandNorthAfricaAfricaSouthEastAsiaNorthAmericaandCaribbeanEuropeSouthAmericaandCentralAmerica6Description:In2021,therewereestimatedtobearound301,200deathsamongthoseaged60yearsandyoungerduetodiabetesinSouthEastAsia.SouthAmericaandCentralAmericahadthelowestnumberofdiabetes-relateddeathsthatyear.

ReadmoreNote(s):WorldwideSource(s):InternationalDiabetesFederationEstimatedglobalhealthcareexpendituretotreatdiabetesin2007,2021,2030,and2045(inbillionU.S.dollars)Globalhealthcareexpenditureduetodiabetesin2007,2021,2030,and20451,2001,0501,0309661,000800600400200023220072021203020457Description:Between2021and2045theglobalexpendituresfordiabetestreatmentisexpectedtogrowfrom966billionU.S.dollarstojustoveronetrillionU.S.dollars.Diabetescanhavelife-threateningcardiovascular,renalandnervoussystemconsequenceswhenleftuntreated.Diabetesisoneoftheleadingcausesofdeathworldwide.ReadmoreNote(s):WorldwideSource(s):InternationalDiabetesFederationCostperpatientwithdiabetesworldwidebyregionin2021(inU.S.dollars)Averagecostperpersonwithdiabetesgloballybyregion202110,0008,648.69,0008,0007,0006,0005,0004,0003,0002,0001,00004,316.74,118.22,136.91,404Africa1,436.2403.5EuropeMiddleEastandNorthAfricaNorthAmericaandCaribbeanSouthandCentralAmericaSoutheastAsiaWesternPacific8Description:Theaveragecostperdiabeticpatientwasapproximately8,650U.S.dollarsinNorthAmericaandtheCaribbeanin2021.Thisamountwasfargreaterthanforanyotherregion.Withinthisregionspecifically,averagediabetes-relatedhealthexpenditurewasbyfarthehighestintheUnitedStates.ReadmoreNote(s):Worldwide;2021Source(s):InternationalDiabetesFederationConsumptionofanti-diabeticdrugsinselectedcountriesin2022(inDDDper1,000people)Consumptionofanti-diabeticdrugsbyselectcountry2022DDDperthousandpeopleperday60

80

10002040120140160180CanadaFinland*154.7105.6GreeceCzechRepublic*Turkey*Germany*SloveniaUnitedKingdom*Spain98.497.596.393.691.69088.687.485France*PortugalSweden80.579.7Chile9Description:Thestatisticshowstheconsumptionofanti-diabeticdrugsinselectedOECDcountriesin2022-orlatestyearavailable(2021).Asofthatyear,nearly89defineddailydoses(DDD)ofanti-diabeticdrugsweretakeninSpainper1,000people.

ReadmoreNote(s):Worldwide,OECDSource(s):OECDCHAPTER

02PrevalenceofdiabetesinMENAAge-adjustedprevalenceofdiabetesintheMiddleEastandNorthAfricainselectedyearsfrom2000to2045Age-adjustedprevalenceofdiabetesMENAinselectedyears2000-204525%20%20.4%19.6%18.1%15%11%10%7.7%5%0%2000201120212030*2045*11Description:Asof2021,theage-adjustedcomparativeprevalenceofdiabetesintheMiddleEastandNorthAfricawas18.1percent.Thiswasa7.1percentincreaseover2021.Althoughtherateisexpectedtocontinuegrowinginthecomingyears,itisforecasttoincreaseataslowerpacethaninpreviousdecades.ReadmoreNote(s):MENA;2000to2021;20-79years;*Forecasts

Age-adjustedcomparativeprevalenceiscalculatedbyadjustingtheagestructureofastandardpopulation.Adjustingratesprovidesformoreobjectiveandreliableobservations,and[...]

ReadmoreSource(s):InternationalDiabetesFederationNumberofadultswithdiabetesintheMiddleEastandNorthAfricain2021,bycountry(in1,000s)NumberofadultswithdiabetesMENA2021,bycountry12,00010,930.710,0008,0006,0004,0002,00005,450.34,274.12,327.72,013

2,011.41,484.2990.9869.4

866.5

803.4613.9445.6

399.2

396.1

394.9183119.812Description:Asof2021,approximately11millionadultsinEgyptwerediagnosedwithdiabetes.IranhadthesecondhighestnumberofdiabetespatientsintheMiddleEastandNorthAfricaregion.Thetopthreecountriesintermsofdiabetescasesintheregionalsohadsomeofthelargestpopulations.ReadmoreNote(s):Afghanistan,Pakistan,MENA;2021;20-79years;*basedonextrapolationfromsimilarcountriesReadmoreSource(s):InternationalDiabetesFederationNumberofchildrenandadolescentswithType1diabetesintheMiddleEastandNorthAfricainselectedyearsfrom2000to2021(in1,000s)ChildrenandadolescentswithType1diabetesMENAinselectedyears2000-2021children(0-14yearsold)adolescents(0-19yearsold)25020015010050192.5108.964.945.3020002011202113Description:Asof2021,therewereapproximately109thousandchildrenundertheageof14withtype1diabetesintheMiddleEastandNorthAfrica(MENA)region.Therewereabout192thousandchildrenandadolescentsundertheageof19intheregionwithtype1diabetes.ReadmoreNote(s):MENA;2000to2021Source(s):InternationalDiabetesFederationNumberofprediabeticadultsintheMiddleEastandNorthAfricainselectedyearsfrom2011to2045,bytype(in1,000s)NumberofprediabeticadultsMENAinselectedyears2011-2045,bytypeImpairedglucosetoleranceImpairedfastingglucose90,00080,00070,00060,00050,00040,00030,00020,00010,000080,50059,00047,610.847,50035,70028,944.623,900201120212030*2045*14Description:Asof2021,therewereroughly47.6millionadultsintheMiddleEastandNorthAfricawithimpairedglucosetolerance(IGT),and28.9millionadultswithimpairedfastingglucose(IFG).By2045,thenumberofadultswithIGTintheregionisforecasttoreach80.5million,and47.5millionwithIFG.ReadmoreNote(s):MENA;2011to2021;20-79years;*forecastyears

IGT:Impairedglucosetolerance.

IFG:Impairedfastingglucose.ReadmoreSource(s):InternationalDiabetesFederationShareofundiagnoseddiabeticadultsintheMiddleEastandNorthAfricain2021,bycountryShareofadultswithundiagnoseddiabetesMENA2021,bycountry70%64%62%60%50%40%30%20%10%0%50%47.1%46.4%

46.4%45.5%

45.5%

45.5%

45.5%43.6%37.3%35.7%34.5%30.8%

30.8%22.3%20.2%15Description:Asof2021,64percentofadultswhohaddiabetesintheUnitedArabEmirates(UAE)wereundiagnosed.Duringthesameperiod,Jordanhadthelowestshareofundiagnoseddiabeticadultsatroughly20percent.

ReadmoreNote(s):MENA;2021;20-79;*basedonextrapolationfromsimilarcountriesReadmoreSource(s):InternationalDiabetesFederationNumberofdiabetesrelateddeathsintheMiddleEastandNorthAfricain2021,bycountry(in1,000s)NumberofdiabetesrelateddeathsMENA2021,bycountry140122.68120100806047.934020032.0531.4421.7521.7514.068.566.875.715.494.343.782.152.10.890.5416Description:In2021,Egyptrecordednearly123thousanddiabetesrelateddeaths.ThiswasthehighestamongstcountriesintheMiddleEastandNorthAfricaduringtheperiod.Meanwhile,Iraq,thecountrywiththesecondhighestnumberofdiabetesrelateddeathsintheregion,hadapproximately48thousanddeaths.ReadmoreNote(s):Afghanistan,Pakistan,MENA;2021;20-79years;*basedonextrapolationfromsimilarcountriesReadmoreSource(s):InternationalDiabetesFederationCHAPTER

03PrevalenceofobesityinMENAObesityrateamongadultmalesintheMiddleEastandNorthAfricain2022,bycountryObesityrateamongadultmaleMENA2022,bycountry45%40.79%38.88%40%35%30%25%20%15%10%5%38.13%34.2%33.35%32.91%32.48%29.77%

29.53%29.02%28.08%26.79%

26.71%19.92%18.26%16.03%13.79%10.49%0%18Description:In2022,QatarhadthehighestprevalenceofmaleobesityamongstcountriesintheMiddleEastandNorthAfricaatalmost41percent.FourofthesixGulfCooperationCouncil(GCC)countrieshadamaleobesityrateofabove32.9percent.

ReadmoreNote(s):MENA;2022Source(s):WorldObesityFederationObesityrateamongadultfemalesintheMiddleEastandNorthAfricain2022,bycountryObesityrateamongadultfemalesMENA2022,bycountry70%58.99%60%50%40%30%20%10%0%52.46%49.94%49.5%48.34%47.67%47.24%46.1%44.32%42.7%41.21%

40.8%35.3%33.4%32.04%

31.76%31.4%17.7%19Description:In2022,womeninEgypthadthehighestobesityrateamongstcountriesintheMiddleEastandNorthAfrica(MENA)regionatnearly59percent.AllsixGulfCooperationCouncil(GCC)countrieshadanobesityrateofabove40percent.

ReadmoreNote(s):MENA;2022Source(s):WorldObesityFederationObesityrateamongboysintheMiddleEastandNorthAfricain2022,bycountryObesityrateamongboysMENA2022,bycountry35%29.28%30%25%20%15%10%5%23.95%23.37%22.16%

21.95%21.63%

21.58%

21.57%17.54%

17.52%16.24%15.58%15.36%

15.29%14.96%12.36%11.32%5.39%0%20Description:In2022,Qatarhadthehighestobesityrateamongboysbetweentheageof5and19intheMiddleEastandNorthAfrica(MENA)region,at29.28percent.FourofthesixGulfCooperationCouncilcountrieshadanobesityrateofabove22percent.MoroccohadthelowestobesityrateofboysintheMENAregionat5.39percent.ReadmoreNote(s):MENA;2022;5-19yearsSource(s):WorldObesityFederationObesityrateamonggirlsintheMiddleEastandNorthAfricain2022,bycountryObesityrateamonggirlsMENA2022,bycountry25%22.45%21.98%20%15%10%5%18.79%

18.75%

18.73%18.42%15.3%

15.23%15.14%14.74%14.54%

14.46%13.3%11.4%10.03%9.45%8.46%6.02%0%21/statistics/1459709/mena-obesity-rate-girls-by-countryIn2022,Egypthadthehighestobesityrateofgirlsbetween5and19yearsoldamongcountriesintheMiddleEastandNorthAfrica(MENA)regionat22.45percent.FiveofthesixGulfCooperationcountrieshadanobesityrateofabove15percent.

ReadmoreNote(s):MENA;2022;5-19yearsSource(s):WorldObesityFederationShareofmaleandfemaleadultsinSaudiArabiain2023,byweightclassWeightclassofadultrespondentsSaudiArabia2023,bygenderMenWomen50%45%40%35%30%25%20%15%10%5%43.5%39.6%34.7%29.5%23.9%23.5%3.1%2.3%0%Underweight(lessthannormalweight)IdealweightOverweightObese22Description:AccordingtoSaudiArabia'sNationalHealthsurveyin2023,approximately40percentofwomenhadidealbodyweightaccordingtothebodymassindex(BMI).Whereas,approximately43.5percentofmenwereoverweight.

ReadmoreNote(s):SaudiArabia,MENA;April2023toJuly2023;15yearsandolderSource(s):GeneralAuthorityforStatistics(SaudiArabia)ShareofrespondentswithobesityinSaudiArabiain2023,byageandgenderRateofobesitySaudiArabia2023,byageandgenderMenWomen60%50%40%30%50%40.9%46.7%45.5%42.6%39.8%34.7%30.2%32.4%27.9%32.1%29.9%32.1%27.3%23.3%27.1%26.4%24.8%20.1%18.1%18.2%16.5%18.4%20%10%0%16.5%12.1%11.4%10.5%7.1%15-1920-2425-2930-3435-3940-4445-4950-5455-5960-6465-6970-7475-80Over80yearsold23Description:AccordingtoSaudiArabia'sNationalHealthsurveyin2023,theobesityratefortheagesof55and59amongfemalesandmaleswas50percentand47percentrespectively.Thiswastheagegroupwiththehighestrateofobesityamongstsurveyparticipants.ReadmoreNote(s):SaudiArabia,MENA;April2023toJuly2023;15yearsandolderSource(s):GeneralAuthorityforStatistics(SaudiArabia)ShareofmaleandfemalechildreninSaudiArabiain2023,byweightclassWeightclassofchildrenrespondentsSaudiArabia2023,bygenderBoys40.9%Girls45%40%35%30%25%20%15%10%5%41.7%41.6%40.3%11.1%9.9%7.8%6.8%0%Underweight(lessthannormalweight)IdealweightOverweightObese24Description:AccordingtoSaudiArabia'sNationalHealthsurveyin2023,approximately42percentofboysyoungerthan15yearswereunderweightbasedonthebodymassindex(BMI).Whereas,approximately42percentofgirlsinthecountryhadidealweightaccordingtotheirBMI.ReadmoreNote(s):SaudiArabia,MENA;April2023toJuly2023;0-15yearsSource(s):GeneralAuthorityforStatistics(SaudiArabia)ShareofchildrenwithobesityinSaudiArabiain2023,byagegroupandgenderShareofchildrenwithobesitySaudiArabia2023,byagegroupandgender18%15.8%16%14%12%10%8%6%3.9%4%2.7%2%0%0to45to910to1425Description:AccordingtoSaudiArabia'sNationalHealthsurveyin2023,approximately16percentofsurveyedchildrenundertheageof4wereobese.Therateofobesityamongstsurveyedchildrenwaslowerthehighertheagegroup,with2.7percentofchildrenbetween10and14yearsoldreportedbeingobese.ReadmoreNote(s):SaudiArabia,MENA;April2023toJuly2023;0-15yearsSource(s):GeneralAuthorityforStatistics(SaudiArabia)CHAPTER

04DiabetesmedicationandspendinginMENAProjectedtoptherapyareasworldwidein2027,byspending(inbillionU.S.dollars)Toptherapyclassesbyspendingglobalmarket2027forecastSpendinginbillionU.S.dollars150

200050100250300350400OncologyImmunology377177168DiabetesCardiovascular126Respiratory92CentralnervoussystemInfectiousdiseasesGenitourinary/sexualhealthGastrointestinalproductsMentalHealth817458524827Description:Thisstatisticshowsthetoptherapyareasworldwidebyprojectedspendingin2027,inbillionU.S.dollars.By2027,spendingononcologyisprojectedtobeatsome377billionU.S.dollars.Immunologyisprojectedtobesecondwitharound177billiondollarsofspending.ReadmoreNote(s):Worldwide;asofNovember2022Source(s):IQVIATotaldiabetes-relatedhealthexpenditureintheMiddleEastandNorthAfricainselectedyearsfrom2011to2045(inmillionU.S.dollars)Totaldiabetes-relatedhealthexpenditureMENAinselectedyears2000-204550,00046,60043,322.945,00040,00035,00030,00025,00020,00015,00010,0005,00032,580.510,9002011020212030*2045*28Description:Asof2021,thetotaldiabetes-relatedhealthexpenditureintheMiddleEastandNorthAfricawasapproximately32.6billionU.S.dollars.Thiswasroughlythreetimesthelevelofspendingin2011.By2030,thisspendingisexpectedtoincreasetoroughly43billionU.S.dollars.ReadmoreNote(s):MENA;2011to2021;*forecastyearsReadmoreSource(s):InternationalDiabetesFederationCostperpersonwithdiabetesintheMiddleEastandNorthAfricain2021,bycountry(inU.S.dollars)CostperpersonwithdiabetesMENA2021,bycountry2,5002,109.52,017.21,930.82,0001,5001,0005001,823.61,745.31,354.81,324.9980.7862.8850.4Iraq845.2616.5473.7250.5Egypt0UnitedArabEmiratesQatar*

LebanonKuwaitSaudiArabiaIranBahrainJordanAlgeriaOmanTunisia

Morocco29Description:In2021,thecostperpersonwithdiabetesintheUnitedArabEmirateswas2100U.S.dollars,thehighestintheMiddleEastandNorthAfrica(MENA)region.AmongstGulfCooperationCouncil(GCC)countries,Omanhadthelowestcostperpatientwithdiabetesat845U.S.dollars.ReadmoreNote(s):Afghanistan,Pakistan,MENA;2021;20-79years;*basedonextrapolationfromsimilarcountries

Figureshavebeenroundedforbetterunderstanding.ReadmoreSource(s):InternationalDiabetesFederationRevenueofdiabetescaredevicesintheMiddleEastandNorthAfricaregionfrom2016to2028(inmillionU.S.dollars)RevenueofdiabetescaredevicesMENA2016-20281,8001,6001,4001,2001,541.541,384.271,241.251,114.1997.011,0008006004002000892.37803.92681.37557.652020516.152019456.72018417.572017384.1420162021202220232024202520262027202830Description:Therevenueinthe'DiabetesCareDevices'segmentofthemedicaltechnologymarketinMENAwasforecasttocontinuouslyincreasebetween2024and2028byintotal544.5millionU.S.dollars(+54.61percent).Afterthetwelfthconsecutiveincreasingyear,theindicatorisestimatedtoreach1.5billionU.S.dollarsandthereforeanewpeakin2028.Notably,therevenueofthe'DiabetesCareDevices'segmentofthemedicaltechnologymarketwascontinuouslyincreasingoverthepast[...]

ReadmoreNote(s):2016to2028Source(s):Revenueofanti-diabetesdrugsintheMiddleEastandNorthAfricaregionfrom2016to2028(inbillionU.S.dollars)Revenueofanti-diabetesdrugsMENA2016-20283.02.52.842.722.592.462.332.22.11.992.01.631.511.51.341.241.131.00.5201620172018201920202021202220232024202520262027202831Description:Therevenueinthe'Anti-DiabetesDrugs'segme

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