MCE Top Selling Products-MCE生命科学试剂

www.MedChemEHighQualityAffordablePricesQuickDeliveryProfessionalTech-supportTopSellingProductsCitedin30,000+Publications.InVitro/VivoMechanismsofAction.24/7CustomerService!Cell.2023Feb2;186(3):591-606.e23.Nature.2023Jan;613(7942):187-194.DoxycyclinepurchasedfromMCE.S63845,Venetoclax,A-1331852purchasedfromMCE.Cell.2023Jan5;S0092-8674(22)01538-0.Science.2022Nov18;378(6621):eabq7361.HomoharringtoninepurchasedfromMCE.Nocodazole,Milrinone,Hoechst33342purchasedfromMCE.Cell.2023Jan19;186(2):413-427.e17.Science.2022Oct14;378(6616):eabq0132.DAMGOTFA,Deltorphin2TFApurchasedfromMCEIL-18BP,MousepurchasedfromMCE.

Nature.2023Feb;614(7947):326-333.FinerenonepurchasedfromMCE.Nature.2022Dec;612(7941):725-731.ChloroquinepurchasedfromMCE.Science.2022Dec2;378(6623):eabo5503.DAPTpurchasedfromMCE.MCEMasterofBioactiveMoleculesCancerResearchCat.No:HY-13259Cat.No:HY-10219Cat.No:HY-100579MG-132RapamycinFerrostatin-1ProteasomeInhibitormTORInhibitorFerroptosisInhibitor556Citations529Citations284CitationsCat.No:HY-15763Cat.No:HY-19312Cat.No:HY-17394Erastin3-Methyladenine(3-MA)CisplatinFerroptosisInducerPI3KInhibitorDNAAlkylator158Citations475Citations263CitationsCat.No:HY-100558Cat.No:HY-100218ACat.No:HY-16658BBafilomycinA1RSL3Z-VAD-FMKV-ATPaseInhibitorFerroptosisActivatorPanCaspaseInhibitor239Citations95Citations190CitationsCat.No:HY-B0215Cat.No:HY-10162Cat.No:HY-10108AcetylcysteineOlaparibLY294002ROSInhibitorPARPInhibitorPI3KInhibitor210Citations139Citations562CitationsCat.No:HY-10583Cat.No:HY-13757ACat.No:HY-B0015Y-27632dihydrochlorideTamoxifenPaclitaxelROCKInhibitorEstrogenReceptorModulatorAntineoplasticAgent147CitationsCitedbyCell.129CitationsCat.No:HY-13418ACat.No:HY-100523Cat.No:HY-114277DorsomorphinML385SotorasibAMPKInhibitorNRF2InhibitorKRASG12CCovalentInhibitor279Citations182CitationsCitedbyNatGenet.Anti-InfectionResearchCat.No:HY-B1743ACat.No:HY-13433Cat.No:HY-16592PuromycindihydrochlorideThapsigarginBrefeldinAAntibioticCa2+-ATPaseInhibitorCRISPR/Cas9Activator81Citations30CitationsCitedbyNatMicrobiol.Cat.No:HY-100381Cat.No:HY-13434Cat.No:HY-10221NigericinsodiumsaltIonomycinVorinostatNLRP3ActivatorCalciumIonophore/AntibioticHDACInhibitor31CitationsCitedbyCellMolImmunol.72CitationsInflammation/ImmunologyResearchCat.No:HY-17589ACat.No:HY-14648ChloroquineDexamethasoneAutophagy/TLRsInhibitorGRAgonist224Citations86CitationsCat.No:HY-12815ACat.No:HY-11109MCC950sodiumResatorvid(TAK-242)NLRP3InhibitorTLR4Inhibitor96Citations291CitationsCat.No:HY-B0579Cat.No:HY-19363CyclosporinAGW4869CalcineurinInhibitorN-SMaseInhibitor71Citations84Citations

Cat.No:HY-15371ForskolinAdenylateCyclaseActivator59CitationsCat.No:HY-12318IBMXPhosphodiesteraseInhibitorCitedbyMolCell.Cat.No:HY-18739PMASphK/PKCActivator140CitationsNeurologicalDiseaseResearchCat.No:HY-13027Cat.No:HY-114153Cat.No:HY-18749DAPTPLX5622SC79γ-secretaseInhibitorCSF1RInhibitorAktActivator72CitationsCitedbyNature.104CitationsMetabolicDiseaseResearchCat.No:HY-17386Cat.No:HY-B0240Cat.No:HY-B0627RosiglitazoneDisulfiramMetforminPPARγAgonistALDH1InhibitorAMPKActivator53CitationsCitedbyNatCancer.34CitationsCardiovascularDiseaseResearchCat.No:HY-B0468Cat.No:HY-17567ACat.No:HY-18723IsoprenalinehydrochlorideHeparinsodiumsaltYoda1β-adrenergicReceptorAgonistAnticoagulantPiezo1AgonistCitedbyScience.CitedbyCellRes.CitedbyCancerCommun.EndocrinologyResearchCat.No:HY-101952Cat.No:HY-N0583Cat.No:HY-B0141ProstaglandinE2HydrocortisoneEstradiolHormone-likeSubstanceSteroidHormoneFemaleSexHormoneCitedbyCellStemCell.CitedbyNature.35Citationswww.MedChemEInhibitors•ScreeningLibraries•ProteinsRecombinantProteinsCat.No:HY-P7109Cat.No:HY-P7025Cat.No:HY-P7118EGF,HumanIFN-gamma,HumanTGFbeta1/TGFB1,HumanCat.No:HY-P7058Cat.No:HY-P7004Cat.No:HY-P7085TNF-alpha/TNFSF2,HumanFGFbasic/bFGF,HumanM-CSF,MouseFluorescentDyesCat.No:HY-D0969Cat.No:HY-D0940Cat.No:HY-W090090DiOH2DCFDA(Green)BODIPY493/503Cat.No:HY-15534Cat.No:HY-D0041Cat.No:HY-D1301JC-1Calcein-AMBODIPY581/591C11BiochemicalAssayReagentsCat.No:HY-17031Cat.No:HY-Y1891Cat.No:HY-Y0320SBE-β-CDTween80DimethylsulfoxideIsotope-LabeledCompoundsCat.No:HY-15162ACat.No:HY-13631ASCat.No:HY-19939SMMAE-d8Exatecan-d5mesylateVX-984PeptidesCat.No:HY-P1731Cat.No:HY-P0035Cat.No:HY-13443TirzepatideInsulin(human)Exendin-4InhibitoryAntibodiesCat.No:HY-P9906Cat.No:HY-P9908Cat.No:HY-P9912BevacizumabAdalimumabPertuzumabCat.No:HY-P9926Cat.No:HY-P9901Cat.No:HY-P9902Dupilumab Ipilimumab Pembrolizumabwww.MedChemELifeScienceProductsKitsMagneticBeadsCat.No:HY-K0202Cat.No:HY-K0207Cat.No:HY-K0208andAgaroseProteinA/GMagneticBeadsAnti-FlagMagneticBeadsStreptavidinMagneticBeadsInhibitor Cat.No:HY-K0030 Cat.No:HY-K0021 Cat.No:HY-K0010Cocktails DeacetylaseInhibitorCocktailPhosphataseInhibitorCocktailI ProteaseInhibitorCocktailCat.No:HY-K0301Cat.No:HY-K2014Cat.No:HY-K1090CellCountingKit-8PEITransfectionReagentCytotoxicityLDHAssayKitCellCultureandAnalysisCat.No:HY-K1014Cat.No:HY-T1000Cat.No:HY-K0302PolyFastTransfectionReagentFetalBovineSerumCTGCellViabilityDetection(Superfine),UruguayOtherCat.No:HY-K1005Cat.No:HY-K1033Cat.No:HY-K1001KitsUltraHighSensitivityECLKitRNaseInhibitorRIPALysisBuffer(Strong)CustomerValidation案例一细胞：过表达WTNFS1 mutant细胞应用：IP实验(HY-K0202ProteinA/GMagneticBeads)分析在没有奥沙利铂处理的情况下，过表达WTNFS1或NFS1突变体S293A或NFS1突变体S293D的细胞中2937NFS1的丝氨酸磷酸化水平。Citedin:SignalTransductTargetTher.2022Feb28;7(1):54.案例二

293TF-NFS1WTS293AS293DP-SerIP:FlagFlagFlagInputWT

DAPINileRedMerge细胞：G4细胞染色检测突变型和野生型细胞中的TAG应用：用NileRed(HY-D0718)含量，发现在G4-mutantcells中TAG含量显著降低Citedin:NucleicAcidsRes.2022Jun24;50(12):6953-67.G4-mutFormoredetails,pleasevisitouronlinewebsitewww.MedChemE案例三细胞：HaCaT细胞应用：tFNAs逆转TGF-β(HY-P7118,5ng/mL)诱导的HaCaT细胞纤维化。免疫荧光(IF)结果图以及统计分析HaCaT细胞中α-SMA的表达。Citedin:ACSApplMaterInterfaces.2022Apr6;14(13):15069-15079.TGF-βTGF-β+TGF-β+Ctrl125nMT250nMTα-SMAFITCDAPIHighLow

α-SMA***SMA6.01.5****ofα-expression1.0intensityof4.00.52.0Relative0.0ctrlTGF-βTGF-β+TGF-β+Relative0.0125nMT250nMT

*****ctrl TGF-βTGF-β+ TGF-β+125nMT250n