膳食纤维与体重控制

张爱珍zhangAizhen膳食纤维与体重控制Dietaryfiberandweightmanagement膳食纤维与体重控制Dietaryfiberandweightmanagement膳食纤维摄入量与体重、体脂呈负相关Mostbutnotallobservationalstudiesshowedaninverse,sometimesdose-dependentrelationshipbetweenDFconsumptionandbodyweight

水溶性膳食纤维和非水溶性膳食纤维富含膳食纤维的天然食物和膳食纤维制剂

Generally,inhumanstudies,nocleardifferenceregardingweightgainhasbeenshownbetweensolubleandinsolubleDFandfermentableandnonfermentableDF,orbetweenfoodsnaturallyhighinDFandfibersupplements

EpidemiologicsupportthatDFintakepreventsobesityisstrong对体重控制效果类似

膳食纤维与体重控制Dietaryfiberandweightmanagement

膳食纤维控制体重的可能机制

1含亲水基团，吸水膨胀性饱腹感2粘性、吸附性延缓饥饿感34减少营养素吸收5改变肠道激素分泌在大肠内发酵代谢提供能量较少Interventionstudies：theadditionofdietaryfibergenerallydecreasesfoodintakeand,hence,bodyweight.Mechanisms：

InducinggreatersatiationandsatietyDecreasingabsorptionofmacronutrientsAlteringsecretionofguthormonesDecreasinginenergyintakeandbodyweightloss

mechanisms国外的研究：膳食纤维与体重控制DietaryfiberandweightmanagementHowarthetal:meanvaluesforpublishedstudiesindicatethatconsumptionofanadditional14g/dayfiberfor>2daysisassociatedwitha10%decreaseinenergyintakeandbodyweightlossof1.9kgover3.8months

meanenergyintakeinallstudieswasreducedto82%byhigherfiberintakeinoverweight/obesepeopleversus94%inleanpeople;bodyweightlosswas2.4kgversus0.8kgEpidemiologicsupportthatDFintakepreventsobesityisstrong补充DF14g/d能量摄入：减少10%（消瘦者：6%肥胖/超重者：18%）体重：减轻1.9kg（消瘦者：0.8kg肥胖/超重者：2.4kg）对超重/肥胖症患者减轻体重的效果优于健康体重者obeseindividualsmayexhibitagreatersuppressionofenergyintakeandbodyweightloss

实验各组大鼠体重的变化情况(g，)组别实验前体重第2周第6周空白对照组203.5±8.5264.4±19.7367.7±29.4高脂模型组202.2±9.4281.2±16.8☆☆401.7±33.2☆☆MCP低剂量组204.5±7.8287.3±13.1☆☆396.1±31.8☆☆MCP中剂量组203.6±7.3284.7±12.6☆☆398.3±21.5☆☆MCP高剂量组202.5±8.4276.8±12.5☆383.2±30.9我们的研究：MCP对肥胖大鼠血脂及瘦素的调节StudyofDFinrat

实验各组大鼠脏体比的变化情况(g，)

组别3周后肝体比3周后肾体比6周后肝体比6周后肾体比空白对照组2.76±0.220.72±0.032.70±0.160.70±0.06模型对照组3.98±0.31☆☆0.76±0.044.45±0.68☆☆0.67±0.07MCP低剂量组4.06±0.30☆☆0.73±0.024.17±0.49☆☆0.66±0.06MCP中剂量组4.12±0.21☆☆0.74±0.043.93±0.38☆☆△0.64±0.05☆MCP高剂量组4.04±0.45☆☆0.74±0.023.66±0.45☆☆△△0.65±0.03☆☆我们的研究：MCP对肥胖大鼠血脂及瘦素的调节StudyofDFinrat

治疗组（n=129）：补充膳食纤维12～18g/d国内其他研究：膳食纤维对肥胖儿童的治疗作用进食量、摄入总热量、饥饿感、尿D-木糖排出量粪便排泄空腹胰岛素、甘油三酯、胆固醇血红蛋白、血清铜锌浓度无显著差异

身高增长无显著差异

体重、腰围、臀围、腰围/臀围、腰围/身高、BMI

BMI下降程度与膳食纤维食用量高度相关

10d后2m后6m后StudyofDFinpediatricsinChina(11/02)ScientificAdvisoryCommitteeonNutrition(SACN)statementondietary(12/06/08)

:Thereisnoevidenceforanassociationoffibreintakeonweightchangeinchildren

世界各国对膳食纤维的推荐摄入量不同AdeclineinDFintake膳食纤维摄入的现状PresentsituationofDietaryfiberintakeAmericanChina中国传统饮食习惯富含膳食纤维生活水平提高，日常饮食结构改变膳食纤维摄入量减少美国调查研究：成人膳食纤维摄入量约仅达推荐量的50%TheaveragefiberintakeofadultsintheUnitedStates（15g/day）isapproximatelyhalftherecommendedlevels（AmericanHeartAssociationrecommendationof25-30g/day)AdeclineintotalDFintakeandDFdensityispredictedforChinainthefuture.Thismaybeduetothemarkedchangesinthedietaryhabitsoftheyoungergeneration,andisaproblematictrendforChinesehealth.

膳食转型期发展中国家1.继续保持优良的传统饮食习惯2.整个生命周期注重摄入富含膳食纤维的全谷类、豆类和蔬菜水果类等食物对中国超重/肥胖、心脑血管病的预防有很深远的意义Increasingconsumptionofdietaryfiberwithfruits,vegetables,wholegrains,andlegumesacrossthelifecycleisacriticalstepinstemmingtheepidemicofobesityinChina，alsomayhelptodecreasetheprevalenceofcardiovasculardiseaseandT2DM中国饮食与膳食纤维ChinesecuisineandDietaryfiberThehealthbenefitsoftraditionalChinasecuisineshouldbeemphasizedChina膳食纤维食品的现状

PresentsituationofDF’suseDF：ItsuseinthepreventionanddiettherapyofobesityObesity:continuestoincreasedramaticallyintheUnitedStatesandworldwide2007:onlyoneU.S.state(Colorado)hadaprevalenceofobesity＜20%NorthAmerica7000万肥胖症，超重人数更多（60%～70%老年人超重/肥胖）膳食纤维资源丰富