药学英语III知到章节答案智慧树2023年山东中医药大学

药学英语III知到章节测试答案智慧树2023年最新山东中医药大学第一章测试

Which

of

the

following

parts

of

knowledge

of

drugs

should

be

included

in

pharmacology?

（

）

参考答案:

The

history,

source,

physical

and

chemical

properties,

compounding,

biochemical

and

physiological

effects,

mechanisms

of

action,

absorption,

distribution,

biotransformation

and

excretion.

Which

of

the

following

is

what

a

clinician

is

primarily

interested

in

according

to

the

text?

(

)

参考答案:

Drugs

which

are

useful

in

the

prevention,

diagnosis

and

treatment

of

human

disease,

or

in

the

prevention

of

pregnancy.

Why

was

the

physician

not

interested

in

pharmacognosy?

(

)

参考答案:

null

Which

of

the

following

is

the

best

way

of

studying

pharmacology

for

medical

students

and

practitioners?

(

)

参考答案:

to

have

curiosity

that

stimulates

them

to

learn

about

sources

of

drugs

What

are

the

tasks

related

to

medicines

almost

completely

delegated

to

the

pharmacists

now?

(

)

参考答案:

the

preparing,

compounding,

and

dispensing

of

medicines

第二章测试

H.

Mario

Geysen

initially

used

parallel

synthesis

as

a

quick

way

to

identify

which

small

(

)

of

any

given

large

protein

bound

to

an

antibody.

参考答案:

division

Chemists

often

start

a

combinatorial

synthesis

by

attaching

the

first

set

of

building

blocks

to

(

),

microscopic

beads

made

of

polystyrene.

参考答案:

soft

The

chemical

reactions

required

to

link

compounds

to

the

beads

and

later

to

detach

them

(

)

to

the

synthesis

process.

参考答案:

make

easy

In

a

parallel

synthesis,

all

the

products

are

(

)

separately

in

their

own

reaction

vessels.

参考答案:

Assorted

In

many

laboratories

today,

robots

assist

with

the

routine

work

of

parallel

synthesis,

such

as

(

)

small

amounts

of

reactive

molecules

into

the

appropriate

wells.

参考答案:

giving

第三章测试

Pharmaceutics

is

an

interdisciplinary

subject

involving

(

)

参考答案:

formulation,

manufacturing,

physical

pharmacy,

and

biopharmaceutics

Formulation

is

about

the

design,

development

and

evaluation

of

dosage

forms,

(

)

参考答案:

drug

delivery

systems

and

manufacturing

process

Biopharmaceutics

mainly

studies

the

in

vivo

process

of

drugs

and

metabolites

in

humans,

animals

and

tissue

culture,

which

specifically

involves

(

)

参考答案:

absorption,

distribution,

metabolism,

and

excretion

Regarding

the

definition

of

bioavailability

(BA),

BA

is

related

to

(

)

参考答案:

total

plasma

drug

concentration,

and

the

administered

drug

dose

Plasma

drug

concentration

is

affected

by

following

factors

such

as

(

)

参考答案:

all

of

above

第四章测试

Blood

(

)

must

be

monitored

in

diabetics

(and,

in

fact,

most

diseases

are

diagnosed

by

chemical

analysis).

参考答案:

glucos

In

medicine,

analytical

chemistry

is

the

basis

for

(

)

laboratory

tests

which

help

physicians

diagnose

disease

and

chart

progress

in

recovery.

参考答案:

clinical

In

industry,

analytical

chemistry

provides

the

means

of

testing

raw

materials

and

for

assuring

the

quality

of

finished

products

whose

chemical

(

)

is

critical.

参考答案:

composition

(

)

quality

is

often

evaluated

by

testing

suspected

contaminants

using

the

techniques

of

analytical

chemistry.

参考答案:

Environmental

The

formation

of

a

white

precipitate

when

adding

a

solution

of

silver

nitrate

to

a

dissolved

sample

indicates

the

presence

of

(

).

参考答案:

chloride

(

)

spectra

will

give

"fingerprints"

of

organic

compounds

or

their

functional

groups.

参考答案:

Infrared

Chromatography

provides

powerful

(

).

参考答案:

Separation

The

list

of

prohibited

substances

at

the

Olympic

Games

includes

about

500

different

active

constituents,

such

as

(

).

参考答案:

all

of

the

above

Doped

compounds

are

identified

using

the

highly

selective

combination

of

gas

(

)-mass

spectrometry

(GC-MS).

参考答案:

Chromatography

(

)

spectrometry

provides

molecular

structural

data

on

the

compounds.

参考答案:

Mass

第五章测试

What

is

the

meaning

of

HTS?

(

)

参考答案:

High

Throughput

Screening

What

category

does

simvastatin

belong

to?

（

）

参考答案:

lipid

regulating

agents

What

category

does

paclitaxel

belong

to?

(

)

参考答案:

antineoplastic

agents

What

category

does

azithromycin

belong

to?

(

)

参考答案:

antibiotics

of

macrolides

90%to95%of

plants

on

this

planet

have

not

been

investigated

so

far.

（

）

参考答案:

对

To

incorporate

natural

products

in

the

modern

HTS

programmes,

a

natural

product

library

is

not

useful.

（

）

参考答案:

错

Natural

products

have

been

a

source

of

drugs

and

drug

leads.

（

）

参考答案:

对

The

traditional

way

of

discovering

drug

from

natural

product

is

bioassay-guided.

（

）

参考答案:

对

Academia

and

some

semi-academic

research

organizations

usually

apply

modern

approaches

to

natural

product

drug

discovery.

（

）

参考答案:

错

Cephalosporin

C

is

an

antiviral

compound.

（

）

参考答案:

错

第六章测试

(

)

is

generally

directly

related

to

uncertainty

and

is

reduced

through

knowledge

and

best

scientific

practices.

参考答案:

Safety

Because

of

the

(

)

of

the

compound

class,

our

future

nonclinical

development

programs

must

be

considered

largely

on

a

case-by-case

basis.

参考答案:

heterogeneity

Adequate

exposure

needed

for

specific

treatment

regimens

can

be

hindered

by

the

formation

of

(

)

with

drug

neutralization

or

accelerated

clearance.

参考答案:

antidrug

antibodies

Toxicology

programs

with

(

)

administration

of

biologics

often

have

less

long-term

treatments

than

SMDS.

参考答案:

multiple-dose

As

in

the

case

for

small

molecules,

some

toxicological

studies

have

to

be

performed

before

first

use

in

humans.

（

）

参考答案:

错

Small

molecules

generally

do

not

necessarily

need

a

PK

assay

for

quantification

of

the

unchanged

compound

and

its

(major)

metabolite(s).

（

）

参考答案:

错

sample-clean

procedures

routinely

used

for

small

molecules

cannot

usually

be

used

for

biologics.

（

）

参考答案:

对

Essential

reagents

such

as

poly-

or

monoclonal

antibodies

might

not

be

difficult

to

obtain

in

the

early

stages

of

development.

（

）

参考答案:

错

The

activity

assay

is

particularly

useful

for

measuring

the

neutralizing

activity

of

an

ADA,

although

it

was

originally

developed

to

measure

product

efficacy.

（

）

参考答案:

对

Tissue

cross-reactivity

(TCR)

studies

in

a

panel

of

human

tissues

determining

the

level

of

cross-recognition

are

necessary

for

targeted

biologics

such

as

mAbs.

（

）

参考答案:

对

第七章测试

(

)

increases

risk

of

bleeding.

参考答案:

Excessive

warfarin

Which

of

the

following

statements

is

TRUE?

(

)

参考答案:

Drugs

that

are

efficacious

in

clinical

trials

may

not

be

very

effective

in

clinical

uses.

Which

of

following

elements

is

not

involved

in

Patient-oriented

outcomes?

(

)

参考答案:

concentrations

of

cholesterol

Clinicians

often

consider

factors

that

are

somewhat

(

),

such

as

personal

experience,

anecdotes,

peer

practices,

and

expert

opinions.

参考答案:

subjective

The

intuitive

standard

used

for

the

measurement

of

efficacy

and

safety

in

medical

history

are

no

longer

used

today.

（

）

参考答案:

错

Unlike

effectiveness,

efficacy

cannot

be

evaluated

accurately

even

in

an

ideal

environment.

（

）

参考答案:

错

Surrogate

outcomes

are

preferred

measures

of

efficacy

than

patient-oriented

outcomes,

because

they

can

be

much

more

feasible

to

use.

（

）

参考答案:

错

Adverse

effects

may

only

be

fully

known

after

a

drug

has

been

in

widespread

clinical

use

for

a

long

time.

（

）

参考答案:

对

Even

a

drug

that

causes

many

more

harms

than

benefits,

it

may

still

be

worth

prescribing

to

patients.

（

）

参考答案:

对

A

drug

with

wide

therapeutic

window

is

often

safer

than

those

with

narrow

ones.

（

）

参考答案:

对

第八章测试

(

)

is

the

drug

regulatory

agency

in

the

UK.

参考答案:

MHRA

Which

of

the

following

statements

about

the

US

and

the

UK

requirements

on

GMP

is

NOT

true?

(

)

参考答案:

The

UK

GMP

was

mandatory

Which

of

the

following

statements

on

the

manufacture

of

API

is

NOT

true?

(

)

参考答案:

Impurities

present

in

final

API

will

be

removed

“Starting

material”

includes

(

)

参考答案:

both

A

and

B

GMP

compliance

is

a

requirement

only

for

the

manufacture

of

drug

products.

（

）

参考答案:

错

According

to

FD&C

Act,

only

drug

products

shall

be

manufactured

in

accordance

with

cGMP.

（

）

参考答案:

错

ICH

Q7

A

is

a

worldwide

guidance

for

the

manufacture

of

drug

products

for

both

commercial

and

R&D

purposes.

（

）

参考答案:

对

Same

as

that

in

the

USA,

all

drug

products

are

inspected

by

the

regulatory

authority

for

compliance

to

GMP

in

the

UK.

（

）

参考答案:

错

Impurities

in

the

final

API

will

be

removed

because

it

will

influence

the

quality

of

drug

products.

（

）

参考答案:

错

Each

stage

of

A

PI

production

will

influence

the

quality

of

final

API.

（

）

参考答案:

错

第九章测试

Which

of

the

following

statements

is

right

according

to

the

passage?

(

)

参考答案:

There

is

a

relationship

between

the

significance

of

the

contraindications

and

the

likelihood

of

occurrence

and

the

size

of

population.

In

a

drug

insert,

pharmacokinetic

effects

are

included

in

(

)

section

参考答案:

Drug

Interaction

Some

information

in

FPI

Contents

section

is

cross-referenced

in

(

)

section.

参考答案:

Highlights

of

Prescribing

Information

When

the

ADR

requires

adjusting

drug

dosage

or

regimen,

discontinuing

the

drug

and

evaluating

the

patient

for

medication

compliance,

it

means

that

the

ADR

associated

with

use

of

the

drug

is

(

).

参考答案:

clinically

significant

In

the

1980s,

health

practitioners

found

it

easy

to

get

specific

information

and

to

distinguish

critical

information

from

less

important

issues

in

the

package

insert.

（

）

参考答案:

错

As

far

as

the

function

of

the

package

insert

is

concerned,

the

FDA

finds

that

it

is

usually

time-intensive

and

clinically

inefficient

for

many

practitioners

to

get

the

information

they

need,

because

the

package

insert

form