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Author:DennisMcCulloughCleanDesignPrinciples‘Do/Don’ts’forFilters/StrainersMicro/CleanDesignDo-Don’tsareprimarilyreferencetrainingmaterials;forP&Gprojectexecution,alwaysrefertotheCleanDesignStandards.Micro/CleanDesignPrinciplesCleanDesignforFilters/StrainersFilters/StrainersDesign:StrainersBasketStart-upIn-LineFiltersSieveDepthMembranePipeConnectionsCIP/SIPMINIMALRISK(=standardfornewequipment)MODERATERISKHIGHRISK316LorbetterSS*SS316Not316SSMinimumRa0.8μm(32μinch)Ra0.8-1.0μm(32-42μinch)MuchhigherRaInternalsurfaceshavenopitting,roughness,orcorrosionInternalsurfaceshaveroughnessbutnopittingorcorrosionInternalsurfaceshavepitting,roughness,andcorrosionCheckyourMOCcompatibilitywithyourproduct&sanitizingagentwithCETL!

*Incaseofnewrawmaterialsorcorrosivematerials,refertoCETLMaterialEngineeringexpertMicro/CleanDesignPrinciplesFilters/StrainersMaterialsofConstructionMoredetails:SeeP&GCleanDesignStandardsoncGMPsiteCleanDesignSpecsforFilters/StrainersDrainable:Thedesignofthefilter/strainermustallowforliquidtobedrainedfromthepipingflowpath.Installinlowpointofpiping.Cleanable&Sanitizable:ThepreferredmethodforcleaningisCIP/SIP(cleaninplace,sanitizeinplace).Thefilter/strainermaterialsofconstructionmustbeabletowithstandCIP&SIPcleaningagentsandtemperatures.

Micro/CleanDesignPrinciplesFilters/StrainersDesignSpecifythecleaningandsanitizationmethodtothefilter/strainersupplier!!“Do”Micro/CleanDesignPrinciplesExample:BasketStrainerDesignStrainersDesignFluidpassesintotheunitwherelargeparticlesorforeignmaterialsarecollectedbytheperforatedscreen.Thefluidpassesbackthroughthescreenandbackintotheprocesspipingsystem.BasketStrainersarethebestoptionwhenlargeamountsofforeignmaterialwillbecollectedandfrequentcleaningisnecessary.Note:Minimalriskprovidedbasketstraineriscapableofbeingbackwashedpriortocleaningandsanitization.Micro/CleanDesignPrinciplesStrainersDesignExample:Start-upStrainerDesign

*SuitableforinitialcommissioningortestrunsONLY.DoesnotmeetsanitarydesignduetodisassemblyrequirementspriortoC&S.Start-upstrainersunitshallonlybeusedwhenasuitableBasketStrainerorIn-lineStrainerarenotavailable.“Don’t”*Micro/CleanDesignPrinciplesStrainersDesign“Do”Y-Strainer&“Don’t”In-LineStrainerNote:DonotuseinternalthreaddesignIn-lineStrainersarethebeststraineroptionwhensmallamountsofforeignmaterialswillbecollected,andfrequentcleaningisnotnecessary.Y-strainerversionprovidegreaterlevelofsanitarydesign.MeetsONLYmoderatemicrorisk.Micro/CleanDesignPrinciples“Don’t”StrainersDesignIn-linestrainersdonotmeetsanitarydesignduetodisassemblyrequirementspriortoC&S.ReplacingthecartridgerequiresadditionalC&Ssteps.Extremelydifficulttoclean.Example:In-LineStrainerDesign

Micro/CleanDesignPrinciplesStrainersDesign“Don’t”Example:SieveStrainerDesignNotrecommendedforsanitarydesignduetotheirlowparticulateholdingcapacity,stainlesssteelmeshscreenfilterswillrequirefrequentbackwashingifexposedtoheavilyparticulateladenstreamsMicro/CleanDesignPrinciplesFilterDesignExample:DepthFilterDesignDepthFiltersareatypeoffiltermediathatreliesonafibermattocaptureparticulate.Theyarecapturedinporesformedbycrossedfibersinthefibermat.Thefibersareheldtogetherbythemechanicalstrengthoftheinterwovenfibers.AlthoughDepthFiltershaveaveryhighparticulateholdingcapability,theyaredifficulttobackwashduetothetrappingofparticulateintheinterlockedfibermatrix.Note:Specify316LSSDepthFiltercontaining316LSSmatwithbackwashingdesign.PallFilters,USFilterpossiblevendorsources.“Do”Micro/CleanDesignPrinciplesFilterDesignExample:MembraneFilterDesignIfaprocessstreamrequiressterilizationbyfiltrationoraveryhighparticulateremovalrequirementisspecified,thenaMembraneFilterwillberequiredNote:Acceptableifsanitaryhousingssanitaryhousingsspecifiedforthefilters“Do”Micro/CleanDesignPrinciplesFilterDesign“Do”Example:MembraneFilterDesignMicro/CleanDesignPrinciplesWhy?Crevicesinapipingsystemcanharborbacteriaandaredifficulttoclean.MinimizeCrevices(productaccumulation)–prefermachineweldconnectionswhenpossiblePipeConnections&Systems“Do”SanitaryTri-ClampSealingRingJointClampSanitaryScrewconnectionExternalThreadpreventsproductaccumulationSealing“O”ringMicro/CleanDesignPrinciples“Do”“Don’t”BoltedflangedconnectionsarenotacceptableforuseinsanitaryprocesspipingsystemsbecausetheytrapproductandcannotbecleanedviaCIP(cleaninplace)methods.PipeConnections&SystemsMicro/CleanDesignPrinciples“Do”PipeConnections&SystemsMicro/CleanDesignPrinciplesCleanDesignSpecsforCIP/SIP*Design:InertMaterials316LSSStrainers/filterssupportback-flushingrequirementsforCIP/SIPSurfacefinishRa<0.8microns(32micro-inches)SmoothsurfacesAvoidanceofbio-filmsPreventproduct/materialaccumulationWeldspolishedandgoodqualityProtectedagainstcontaminationfromoutsideenvironment*CIP=Clean-inPlace;SIP=Sanitize-in-PlaceNote:ReferenceCIP/SIP“Do’s”and“Don’ts”Micro/CleanDes

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