Clavulanate-potassium-DataSheet-生命科学试剂-MedChemExpress

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEClavulanatepotassiumCat.No.:HY-A0256ACASNo.:61177-45-5分⼦式:C₈H₈KNO₅分⼦量:237.25作⽤靶点:Bacterial;Antibiotic作⽤通路:Anti-infection储存⽅式:4°C,sealedstorage,awayfrommoisture*Insolvent:-80°C,6months;-20°C,1month(sealed

storage,awayfrommoisture)溶解性数据体外实验H2O:33.33mg/mL(140.48mM;ultrasonicandadjustpHto2withHCl)MassSolvent1mg5mg10mgConcentration制备储备液1mM4.2150mL21.0748mL42.1496mL5mM0.8430mL4.2150mL8.4299mL10mM0.4215mL2.1075mL4.2150mL请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month(sealedstorage,awayfrommoisture)。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。BIOLOGICALACTIVITY⽣物活性Clavulanatepotassium⼀种⾼效的β-lactamase抑制剂，可作为抗⽣素[1][2]。IC50&Targetβ-lactamase[1]体外研究Clavulanatepotassiumhasweakantibacterialactivityagainstmostorganismswhenadministeredalone,butgivenincombinationwithbeta-lactamantibioticspreventsantibioticinactivationbymicrobiallactamase[1].1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemEClavulanatepotassium(0.25mg/L,0.5mg/L)causesarelativelyslowinhibitionofgrowth,andahigherconcentration(1mg/L)isonlymarginallymoreeffectivethan0.5mg/L[2].户使⽤本产品发表的科研⽂献•NatCommun.2022Mar2;13(1):1116.•Genomics.2022:110527.•BiomedResInt.2018Jul2;2018:3579832.Seemorecustomervalidationsonwww.MedChemEREFERENCES[1].ReadingC,etal.ClavulanicAcid:aBeta-Lactamase-InhibitingBeta-LactamfromStreptomycesclavuligerus.AntimicrobAgentsChemother.1977May;11(5):852–857.[2].StokesDH,etal.Bactericidaleffectsofamoxycillin/clavulanicacidagainstintracellularLegionellapneumophilaintissueculturestudies.JAntimicrobChemother.1989Apr;23(4):547-56.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-