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抗生素的耐药危机(英文)课件1THEANTIBIOTICRESISTANCECRISISTHE2THEANTIBIOTICRESISTANCECRISISHISTORYOFBACTERIAHISTORYOFANTIBIOTICSRESISTANCETHEPROBLEMNOWNEVADANSFORANTIBIOTICAWARENESSTHEANTIBIOTICHISTORYOFBA3抗生素的耐药危机(英文)课件4抗生素的耐药危机(英文)课件5HISTORYOFBACTERIAREPRODUCTIONBINARYFISSIONCLONEOFORIGINALWITHSAMEDNAFASTPROCESSONEBACTERIUMCANPRODUCEONEBILLIONCLONESINTENHOURSHISTORYOFBACTERIAREPRODUCTIO6HISTORYOFBACTERIAREPRODUCTIONMUTATIONACHANGE,SOTHATTHE“NEW”BACTERIAISSLIGHTLYDIFFERENTTHANTHEORIGINALHISTORYOFBACTERIAREPRODUCTIO7HISTORYOFBACTERIAREPRODUCTIONIFTHEENVIRONMENTISRIGHT,THE“NEW”BACTERIAMAYSURVIVEBETTERANDREPRODUCE,PASSINGALONGTHEMUTATIONHISTORYOFBACTERIAREPRODUCTIO8HISTORYOFANTIBIOTICS1928–DR.FLEMINGDISCOVERSPENICILLINFROMBREADMOLD1944–U.S.MILITARYTAKESPENICILLINTOTHEBATTLEFIELD1945–BACTERIAWITHRESISTANCETOPENICILLINISOLATEDHISTORYOFANTIBIOTICS1928–D9HISTORYOFANTIBIOTICS1960s–METHICILLININTRODUCED1991–29%OFSTAPHAUREUSRESISTANT2001–62%OFSTAPHAUREUSRESISTANTRESISTANCEHISTORYOFANTIBIOTICS1960s–10HISTORYOFANTIBIOTICSRESISTANCEBACTERIAMUTATETOPROTECTTHEMSELVESFROMANTIBIOTICSHISTORYOFANTIBIOTICSRESISTAN11HISTORYOFANTIBIOTICSRESISTANCETHEMUTATEDBACTERIASURVIVEAFTERTHEANTIBIOTICSAREGONEHISTORYOFANTIBIOTICSRESISTAN12HISTORYOFANTIBIOTICSRESISTANCEEVENTUALLYTHEREAREMOREANTIBIOTIC-RESISTANTBACTERIATHANNON-RESISTIANTHISTORYOFANTIBIOTICSRESISTAN13HISTORYOFANTIBIOTICSRESISTANCETHEMUTATEDBACTERIAREPRODUCE,PASSINGALONGTHERESISTANCETOTHEIROFFSPRINGHISTORYOFANTIBIOTICSRESISTAN14HISTORYOFANTIBIOTICSRESISTANCEBACTERIACANALSOSWAPGENES,UNDERTHERIGHTCONDITIONS,SODRUG-RESISTANTGERMSCANSHARETHEIRRESISTANCEMECHANISMSHISTORYOFANTIBIOTICSRESISTAN15THEPROBLEMNOW19911999200020011991199920002001THEPROBLEMNOW1991199916THEPROBLEMNOW2000200120002001THEPROBLEMNOW200017THEPROBLEMNOW>50%OFHOSPITALACQUIREDBLOODSTREAMINFECTIONSARECAUSEDBYMETHICILLIN-RESISTANTSTAPHAUREUS(MRSA)>70%OFNURSINGHOMESTAPHINFECTIONSARECAUSEDBYMRSATHEPROBLEMNOW>50%OFHOSPIT18THEPROBLEMNOW“THEREAREPATIENTSTODAYINHOSPITALSFORWHOMTHEREARENOEFFECTIVETHERAPIES.”GaryDoernDirectorofClinicalMicrobiologyUniversityofIowaTHEPROBLEMNOW“THEREARE19NEVADANSFORANTIBIOTICAWARENESS

WHOWEAREWHATWEHAVEDONEWHATWEAREDOINGRESULTSHOWCANYOUHELPNEVADANSFORWHOWEARE20NEVADANSFORANTIBIOTICAWARENESSWHOWEAREASTATEWIDETASKFORCETHATHASBEENINEXISTENCESINCEFEBRUARY20013SUBCOMMITTEESPUBLICAWARENESSPROVIDEREDUCATIONINFECTIONCONTROLANDSURVEILLANCENEVADANSFORWHOWEAREASTATE21NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPUBLICAWARENESSTV,RADIOSPOTSINSPANISHANDENGLISHAIRING400-500TIMESPERMONTHNEVADALEGISLATUREPASSEDABILLSUPPORTINGNAAGOVERNORGUINNISSUEDAPROCLAMATIONSUPPORTINGNAANEVADANSFORWHATWEHAVEDONE22NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPUBLICAWARENESSEDUCATIONPROGRAMSWERECOMPLETEDFORALLCLARKANDWASHOECOUNTYSCHOOLNURSESANDTHEIRAIDESA9THAND10THGRADESUPPLEMENTALCURRICULUMBASEDONTHESURVIVORSERIESISBEINGUSEDINCLARKANDWASHOECOUNTIESNEVADANSFORWHATWEHAVEDONE23NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPUBLICAWARENESS>10,000BOOKMARKSHAVEBEENDISTRIBUTEDBYTHEWASHOECOUNTYLIBRARYSYSTEMMAJORPHARMACYCHAINSHAVEDISTRIBUTED>100,000BOOKMARKSNEVADANSFORWHATWEHAVEDONE24NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPUBLICAWARENESSEMERGENCYROOMSANDQUICK-CARECENTERSAREDISPLAYINGOURPOSTERSANDBROCHURES(SPANISH&ENGLISH)RECENTANTIBIOTICRESISTANCEINFORMATIONHASBEENSENTTOALLCLARKCOUNTYCHILDCARECENTERSNEVADANSFORWHATWEHAVEDONE25NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPROVIDEREDUCATIONPROVIDERPACKETSWERESENTTOALLPRIMARYCAREPHYSICIANSIN2002AND2003ACMEPROGRAMWASCONDUCTEDFOR>150PHYSICIANSINNORTHERNNEVADAAHOSPITALISTEDUCATIONPROGRAMHASBEENIMPLEMENTEDINCLARKCOUNTYNEVADANSFORWHATWEHAVEDONE26NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPROVIDEREDUCATIONPRESENTATIONSTOUMCSECOND-YEARRESIDENTSHAVEBEENMADEINDIVIDUALPROVIDEROFFICEVISITSINELKOANDPAHRUMPHAVEBEENCOMPLETEDAPRESENTATIONREGARDINGNAAWASMADEATACDCCONFERENCENEVADANSFORWHATWEHAVEDONE27NEVADANSFORANTIBIOTICAWARENESSWHATWEAREDOINGEXPANDINGEFFORTSTOIMPROVEINFECTIONCONTROLANDSURVEILLANCEWITHTHECDC12-STEPPROGRAMFINISHINGDEVELOPMENTOFNAAWEBSITEDEVELOPINGANDIMPLEMENTINGCHILDCAREPROFESSIONALPROGRAMINCREASINGMEDICALSCHOOL/RESIDENCYINVOLVEMENTNEVADANSFORWHATWEAREDOING28NEVADANSFORANTIBIOTICAWARENESSWHATWEAREDOINGINCREASINGPHARMACYSCHOOLINVOLVEMENTEXPANDINGEFFORTSTOIMPROVEINFECTIONCONTROLINLONGTERMCAREANDSKILLEDNURSINGFACILITIESCONTINUINGMEDIACAMPAIGNANDALLOTHERCURRENTEFFORTSTOWARDPUBLICANDPROVIDEREDUCATIONNEVADANSFORWHATWEAREDOING29NEVADANSFORANTIBIOTICAWARENESSRESULTSNumberofAntibioticScriptsFilledperMemberperMonthHPNConsolidated(CommercialandMedicare)2000–2002NEVADANSFORRESULTSNumberof30NEVADANSFORANTIBIOTICAWARENESSCONTINUEWORKINGWITHTHEINFECTIONCONTROL/SURVEILLANCECOMMITTEEINVITEUSTOMAKEAPRESENTATIONTOYOURPHARMACYANDTHERAPEUTICCOMMITTEEWORKWITHHEALTHINSIGHTINOURSURGICALINFECTIONPREVENTIONPROGRAMHOWYOUCANHELPNEVADANSFORCONTINUEWORKING31抗生素的耐药危机(英文)课件32THEANTIBIOTICRESISTANCECRISISTHE33THEANTIBIOTICRESISTANCECRISISHISTORYOFBACTERIAHISTORYOFANTIBIOTICSRESISTANCETHEPROBLEMNOWNEVADANSFORANTIBIOTICAWARENESSTHEANTIBIOTICHISTORYOFBA34抗生素的耐药危机(英文)课件35抗生素的耐药危机(英文)课件36HISTORYOFBACTERIAREPRODUCTIONBINARYFISSIONCLONEOFORIGINALWITHSAMEDNAFASTPROCESSONEBACTERIUMCANPRODUCEONEBILLIONCLONESINTENHOURSHISTORYOFBACTERIAREPRODUCTIO37HISTORYOFBACTERIAREPRODUCTIONMUTATIONACHANGE,SOTHATTHE“NEW”BACTERIAISSLIGHTLYDIFFERENTTHANTHEORIGINALHISTORYOFBACTERIAREPRODUCTIO38HISTORYOFBACTERIAREPRODUCTIONIFTHEENVIRONMENTISRIGHT,THE“NEW”BACTERIAMAYSURVIVEBETTERANDREPRODUCE,PASSINGALONGTHEMUTATIONHISTORYOFBACTERIAREPRODUCTIO39HISTORYOFANTIBIOTICS1928–DR.FLEMINGDISCOVERSPENICILLINFROMBREADMOLD1944–U.S.MILITARYTAKESPENICILLINTOTHEBATTLEFIELD1945–BACTERIAWITHRESISTANCETOPENICILLINISOLATEDHISTORYOFANTIBIOTICS1928–D40HISTORYOFANTIBIOTICS1960s–METHICILLININTRODUCED1991–29%OFSTAPHAUREUSRESISTANT2001–62%OFSTAPHAUREUSRESISTANTRESISTANCEHISTORYOFANTIBIOTICS1960s–41HISTORYOFANTIBIOTICSRESISTANCEBACTERIAMUTATETOPROTECTTHEMSELVESFROMANTIBIOTICSHISTORYOFANTIBIOTICSRESISTAN42HISTORYOFANTIBIOTICSRESISTANCETHEMUTATEDBACTERIASURVIVEAFTERTHEANTIBIOTICSAREGONEHISTORYOFANTIBIOTICSRESISTAN43HISTORYOFANTIBIOTICSRESISTANCEEVENTUALLYTHEREAREMOREANTIBIOTIC-RESISTANTBACTERIATHANNON-RESISTIANTHISTORYOFANTIBIOTICSRESISTAN44HISTORYOFANTIBIOTICSRESISTANCETHEMUTATEDBACTERIAREPRODUCE,PASSINGALONGTHERESISTANCETOTHEIROFFSPRINGHISTORYOFANTIBIOTICSRESISTAN45HISTORYOFANTIBIOTICSRESISTANCEBACTERIACANALSOSWAPGENES,UNDERTHERIGHTCONDITIONS,SODRUG-RESISTANTGERMSCANSHARETHEIRRESISTANCEMECHANISMSHISTORYOFANTIBIOTICSRESISTAN46THEPROBLEMNOW19911999200020011991199920002001THEPROBLEMNOW1991199947THEPROBLEMNOW2000200120002001THEPROBLEMNOW200048THEPROBLEMNOW>50%OFHOSPITALACQUIREDBLOODSTREAMINFECTIONSARECAUSEDBYMETHICILLIN-RESISTANTSTAPHAUREUS(MRSA)>70%OFNURSINGHOMESTAPHINFECTIONSARECAUSEDBYMRSATHEPROBLEMNOW>50%OFHOSPIT49THEPROBLEMNOW“THEREAREPATIENTSTODAYINHOSPITALSFORWHOMTHEREARENOEFFECTIVETHERAPIES.”GaryDoernDirectorofClinicalMicrobiologyUniversityofIowaTHEPROBLEMNOW“THEREARE50NEVADANSFORANTIBIOTICAWARENESS

WHOWEAREWHATWEHAVEDONEWHATWEAREDOINGRESULTSHOWCANYOUHELPNEVADANSFORWHOWEARE51NEVADANSFORANTIBIOTICAWARENESSWHOWEAREASTATEWIDETASKFORCETHATHASBEENINEXISTENCESINCEFEBRUARY20013SUBCOMMITTEESPUBLICAWARENESSPROVIDEREDUCATIONINFECTIONCONTROLANDSURVEILLANCENEVADANSFORWHOWEAREASTATE52NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPUBLICAWARENESSTV,RADIOSPOTSINSPANISHANDENGLISHAIRING400-500TIMESPERMONTHNEVADALEGISLATUREPASSEDABILLSUPPORTINGNAAGOVERNORGUINNISSUEDAPROCLAMATIONSUPPORTINGNAANEVADANSFORWHATWEHAVEDONE53NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPUBLICAWARENESSEDUCATIONPROGRAMSWERECOMPLETEDFORALLCLARKANDWASHOECOUNTYSCHOOLNURSESANDTHEIRAIDESA9THAND10THGRADESUPPLEMENTALCURRICULUMBASEDONTHESURVIVORSERIESISBEINGUSEDINCLARKANDWASHOECOUNTIESNEVADANSFORWHATWEHAVEDONE54NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPUBLICAWARENESS>10,000BOOKMARKSHAVEBEENDISTRIBUTEDBYTHEWASHOECOUNTYLIBRARYSYSTEMMAJORPHARMACYCHAINSHAVEDISTRIBUTED>100,000BOOKMARKSNEVADANSFORWHATWEHAVEDONE55NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPUBLICAWARENESSEMERGENCYROOMSANDQUICK-CARECENTERSAREDISPLAYINGOURPOSTERSANDBROCHURES(SPANISH&ENGLISH)RECENTANTIBIOTICRESISTANCEINFORMATIONHASBEENSENTTOALLCLARKCOUNTYCHILDCARECENTERSNEVADANSFORWHATWEHAVEDONE56NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPROVIDEREDUCATIONPROVIDERPACKETSWERESENTTOALLPRIMARYCAREPHYSICIANSIN2002AND2003ACMEPROGRAMWASCONDUCTEDFOR>150PHYSICIANSINNORTHERNNEVADAAHOSPITALISTEDUCATIONPROGRAMHASBEENIMPLEMENTEDINCLARKCOUNTYNEVADANSFORWHATWEHAVEDONE57NEVADANSFORANTIBIOTICAWARENESSWHATWEHAVEDONEPROVIDEREDUCATIONPRESENTATIONSTOUMCSECOND-YEARRESIDENTSHAVEBEENMADEINDIVIDUALPROVIDEROFFICEVISITSINELKOANDPAHRUMPHAVEBEENCOMPLETEDAPRESENTATIONREGARDINGNAAWASMA

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