COPD患者的镇静问题课件

COPD患者应慎重应用镇静1、COPD的镇静催眠问题；2、长期口服镇静催眠药物的呼吸不良事件；3、短期静脉应用镇静的心肺问题；4、无创辅助通气时应用镇静的问题COPD与睡眠sevenstudieswithpatientswithCOPDshowedadverserespiratoryeffectsassociatedwithNBBRAsandbenzodiazepines,wheresevenothersdidnot.moreadverseeffectswereseenwithlongeractingbenzodiazepines.Limitedduration.

varyingseverityofCOPD.

Differentpharmacodynamics

variousrespiratoryparameters

1、StegeG,VosPJ,vandenElshoutFJ,RichardDPN,vandeVenMJ,HeijdraYF.Sleep,hypnoticsandchronicobstructivepulmonarydisease.RespirMed.2008.102(6):801-14.

hypnotics,particularlybenzodiazepines,shouldbeavoided,ifpossibley,althoughthereisevidencethatsomehypnotics,suchaszolpidem,canbeusedinlesssevereCOPDwithoutsignificantadverseeffectsongasexchange1.1.CelliBR,MacNeeW.StandardsforthediagnosisandtreatmentofpatientswithCOPD:asummaryoftheATS/ERSpositionpaper.EurRespirJ2004;23:932–46.长期口服镇静催眠药物的呼吸不良事件ChungWS,LaiCY,LinCL,KaoCH.AdverseRespiratoryEventsAssociatedWithHypnoticsUseinPatientsofChronicObstructivePulmonaryDisease:APopulation-BasedCase-ControlStudy.Medicine(Baltimore).2015.94(27):e1110.hypnotics,especiallyinactiveusers(0–30days),isassociatedwithanincreasedriskofadverserespiratoryeventsintheseCOPDpatients.ThisincreasedriskofadverserespiratoryeventsemphasizesthatevaluatingthecurrentinsomniatreatmentswithhypnoticsfortheseCOPDpatientsisnecessaryandimportant.CliniciansshouldkeepalertofthepotentialriskofadverserespiratoryeventsintheseCOPDpatientsbeforeprescribinghypnotics.ChungWS,LaiCY,LinCL,KaoCH.AdverseRespiratoryEventsAssociatedWithHypnoticsUseinPatientsofChronicObstructivePulmonaryDisease:APopulation-BasedCase-ControlStudy.Medicine(Baltimore).2015.94(27):e1110.短期镇静对高龄COPD患者心肺功能的影响XuCX,ChenX,JiaY,etal.Stepwisesedationforelderlypatientswithmild/moderateCOPDduringuppergastrointestinalendoscopy.WorldJGastroenterol.2013.19(29):4791-8.XuCX,ChenX,JiaY,etal.Stepwisesedationforelderlypatientswithmild/moderateCOPDduringuppergastrointestinalendoscopy.WorldJGastroenterol.2013.19(29):4791-8.XuCX,ChenX,JiaY,etal.Stepwisesedationforelderlypatientswithmild/moderateCOPDduringuppergastrointestinalendoscopy.WorldJGastroenterol.2013.19(29):4791-8.无创辅助通气中的镇静问题XuCX,ChenX,JiaY,etal.Stepwisesedationforelderlypatientswithmild/moderateCOPDduringuppergastrointestinalendoscopy.WorldJGastroenterol.2013.19(29):4791-8.小结COPD患者普遍存在有睡眠问题，提高生活质量指数可能会遇到镇静安眠问题；短期镇静治