食管癌英文培训教材课件

1、食管癌英文食管癌英文ContentAnatomy of the EsophagusSummaryPathogeny(发病机制)Clinical featureDiagnoseDifferential diagnosisExerciseContentAnatomy of the EsophaguAnatomy of the EsophagusThe esophagus is a muscular tube, which is a digestive organ between the throat and stomach.Anatomy of the EsophagusThe esPhysiol

2、ogical stenosis of esophagusFirst: The junction of the pharynx(咽) and esophagus.Second: located in the back of left principal bronchus.Third: Esophageal hiatus(食管裂孔). Physiological stenosis of esop3 Sections of the esophagus The upper segmentThe middle segment （Carcinoma occur most frequent） The low

3、er segmentTracheal bifurcation (气管分叉)3 Sections of the esophagus ThSummaryCarcinoma of the esophagus is a common malignant tumor that occurs in a population cover 40 years old ,and in predilection for male(好发于男性).SummaryCarcinoma of the esophaPrevalence and mortality There are more than 300,000 peop

4、le worldwide died from esophageal cancer each year , and 150,000 of them are Chinese.Prevalence and mortality ThereLimiting filling defect(局限性充盈缺损)Tracheal bifurcation (气管分叉)M,63Y, Progressivedysphagia20dLimiting filling defect(局限性充盈缺损)广泛侵犯食管全层,形成腔外肿物，管腔狭窄，表面可见溃疡On a widened upper segment with fluid

5、 levelOn a widened upper segment with fluid levelWhen the tumorinvadethe trachea , tracheoesophageal fistula(气管食管瘘)T1W enhance scanning shows a lump in the trachea and be enhanced like the carcinoma.Limiting filling defect(局限性充盈缺损)Anatomy of the EsophagusEnhanced CT scanshowed vascular tortuositygro

6、up remarkable enhancement and delayedenhancement.3 Sections of the esophagusnicheCan u remember the 3 physiological stenosis of esophagus? (In this question u can answer it in Chinese)Medullary type(髓质型)The upper segmentAnatomy of the EsophagusAnatomy of the EsophagusPathogeny1. Nitrosamine(亚硝胺)2. F

7、ungus(真菌)3. Vitamin deficiency4. Dietary habitsLimiting filling defect(局限性充盈缺 NitrosamineNitrosaminescontent of thesefoodsare very high NitrosamineNitrosaminesconteClinical feature（Carcinoma occur most frequent）Middle and advanced stageT1W enhance scanning shows a lump in the trachea and be enhanced

8、 like the carcinoma.Intermittentdysphagia(间歇性吞咽困难)Can u remember the 3 physiological stenosis of esophagus? (In this question u can answer it in Chinese)Anatomy of the EsophagusAnatomy of the EsophagusLower esophagus become thin like a beak(鸟嘴征)Computed Tomography(CT)First: The junction of the phary

9、nx(咽) and esophagus.Beadedfilling defect(串珠样充盈缺损)Paraesophagealfat layerfuzzy,disappear.Paraesophagealfat layerfuzzy,disappear.Achalasia of cardia and esophagus(食管贲门失弛缓征)Magnetic Resonance Imaging(MR)Cancer invade the tracheaOn a widened upper segment with fluid levelTracheal bifurcation (气管分叉)Bariu

10、m streamslow ortemporaryresidence(钡剂流动缓慢或一过性滞留)Cachexia(恶病质)Limiting filling defect(局限性充盈缺损)The upper segmentLeiomyoma of the esophagus(食道平滑肌瘤).Cancer invade the tracheaOn a widened upper segment with fluid levelWhen the tumorinvadethe trachea , tracheoesophageal fistula(气管食管瘘)Enhanced scanning show

11、edmild enhancement oftumor.On a widened upper segment with fluid levelSmallnodules(小结节)Constrictive typeAnatomy of the EsophagusSingle ormultiple smallniches(龛影)When the tumorinvadethe trachea , tracheoesophageal fistula(气管食管瘘)Mushroom typeWithout mucosal fold break.On a widened upper segment with f

12、luid levelClinical feature In early stage Symptoms are often not obvious, but when swallowing the coarse food ,different degrees of uncomfortable feelings may occur.Clinical featureOn a widened uClinical featureIn the middle and advanced stage Progressivedysphagia (进行性吞咽困难) When the tumorinvadethe t

13、rachea , tracheoesophageal fistula(气管食管瘘) Cachexia(恶病质)Clinical featureIn the middle Classification of esophagealcancer1. Ulcerative type(溃疡型)2. Mushroom type(蕈伞型)3. Constrictive type(缩窄型)4. Medullary type(髓质型)Classification of esophagealcPathogeny(发病机制)Limiting filling defect(局限性充盈缺损)Anatomy of the

14、 EsophagusLimiting filling defect(局限性充盈缺损)Tracheal bifurcation (气管分叉)Anatomy of the EsophagusLeiomyoma of the esophagus(食道平滑肌瘤).Anatomy of the EsophagusT1W enhance scanning shows a lump in the trachea and be enhanced like the carcinoma.On a widened upper segment with fluid levelCan u remember the 3

15、physiological stenosis of esophagus? (In this question u can answer it in Chinese)Enhanced CT scanshowed vascular tortuositygroup remarkable enhancement and delayedenhancement.XraybariummealDifferential diagnosisFungus(真菌)protrude type(隆起型)Early stagePostoperationPeripheralorgan got involvedorlymph

16、node metastasis.（Carcinoma occur most frequent）On a widened upper segment with fluid level广泛侵犯食管全层,形成腔外肿物，管腔狭窄，表面可见溃疡Leiomyoma of the esophagus(食管平滑肌瘤)Diagnose1. Xraybariummeal2. Computed Tomography(CT)3. Magnetic Resonance Imaging(MR)Pathogeny(发病机制)Diagnose1. Xray1. Xraybariummeal(1). Early stageEs

17、ophagealmucosal folds be beak(粘膜迂曲、断裂)Single ormultiple smallniches(龛影)Limiting filling defect(局限性充盈缺损)Barium streamslow ortemporaryresidence(钡剂流动缓慢或一过性滞留)1. Xraybariummeal(1). Early PostoperationRecurPostoperationSmallnodules(小结节)Smallnodules(小结节)protrude type(隆起型)protrude type(隆起型)Earlyulcerative

18、typeEarlyulcerative type Early constrictive type Early constrictive type(2). Middle and advanced stagea. Ulcerative type(溃疡型) niche The surrounding of the tumor become bulged , and the folds of mucous become damaged. (周围隆起,粘膜皱襞破坏)(2). Middle and advanced stage Filling defectAn expand over the tumorb

19、 .Mushroom type Filling defectb .Mushroom typc . Constrictive typeM,63Y, Progressivedysphagia20d c . Constrictive typeM,63Y, Prd. Medullary type广泛侵犯食管全层,形成腔外肿物，管腔狭窄，表面可见溃疡The carcinoma can encroach on the whole-layer of esophagus and make a stenosis,with ulceration on it.d. Medullary type广泛侵犯食管全层,形成

20、腔外2. CT1. Esophagealwall circular or irregular thickening(5mm).2. Cavity lump occurred.3. Paraesophagealfat layerfuzzy,disappear.4. Peripheralorgan got involvedorlymph node metastasis.5. Enhanced scanning showedmild enhancement oftumor.2. CT1. Esophagealwall circul食管癌英文培训教材课件Enhanced scanningEnhance

21、d scanning3. MRThere is a synechia(黏连) between the cancer and the aortic arch.The high signal fat layer exist.3. MRThere is a synechia(黏连) bCancer invade the tracheaT2WIThe fat layer disappeared and the wall of trachea be damaged.T1W enhance scanning shows a lump in the trachea and be enhanced like

22、the carcinoma.Cancer invade the tracheaT2WITDifferential diagnosis1. Achalasia of cardia and esophagus(食管贲门失弛缓征)2. Esophageal varices(食管静脉曲张)3. Leiomyoma of the esophagus(食道平滑肌瘤).Differential diagnosis1. AchalT1W enhance scanning shows a lump in the trachea and be enhanced like the carcinoma.Lower e

23、sophagus become thin like a beak(鸟嘴征)On a widened upper segment with fluid levelMedullary typePrevalence and mortalityPrevalence and mortalityAnatomy of the EsophagusLimiting filling defect(局限性充盈缺损)T2WIThe fat layer disappeared and the wall of trachea be damaged.Tracheal bifurcation (气管分叉)On a widen

24、ed upper segment with fluid levelClinical featureIn early stagePostoperationLimiting filling defect(局限性充盈缺损)Anatomy of the EsophagusWhen the tumorinvadethe trachea , tracheoesophageal fistula(气管食管瘘)Symptoms are often not obvious, but when swallowing the coarse food ,different degrees of uncomfortabl

25、e feelings may occur.1. Achalasia of cardia and esophagusIntermittentdysphagia(间歇性吞咽困难)On a widened upper segment with fluid levelLower esophagus become thin like a beak(鸟嘴征)Without mucosal fold break.T1W enhance scanning shows a l食管癌英文培训教材课件2. Esophageal varicesHave a history of liver cirrhosis, po

26、rtal hypertension.Beadedfilling defect(串珠样充盈缺损)Enhanced CT scanshowed vascular tortuositygroup remarkable enhancement and delayedenhancement.Barium emptying delay, but no obstruction phenomenon.2. Esophageal varicesHave a hi食管癌英文培训教材课件3. Leiomyoma of the esophagus(食管平滑肌瘤)Smooth circular cavity filli

27、ng defect without mucosal fold break and surrounding tissue invasion and metastasis.3. Leiomyoma of the esophagus(食管癌英文培训教材课件Exercise1. Can u remember the 3 physiological stenosis of esophagus? (In this question u can answer it in Chinese)2. Please show us the four types of the carcinoma of esophagu

28、s.3. Tell me which esophagus disease it is in the following pictures.Exercise1. Can u remember the Ulcerative carcinomaUlcerative carcinomaThe endThank you!The endThank you!Earlyulcerative typeIn the middle and advanced stageParaesophagealfat layerfuzzy,disappear.Barium streamslow ortemporaryresiden

29、ce(钡剂流动缓慢或一过性滞留)Enhanced scanning showedmild enhancement oftumor.Esophageal varices(食管静脉曲张)Single ormultiple smallniches(龛影)Enhanced scanning showedmild enhancement oftumor.Middle and advanced stageAnatomy of the EsophagusDietary habitsBeadedfilling defect(串珠样充盈缺损)Achalasia of cardia and esophagusCa

30、n u remember the 3 physiological stenosis of esophagus? (In this question u can answer it in Chinese)Early constrictive typeOn a widened upper segment with fluid levelClinical featureAnatomy of the EsophagusAnatomy of the EsophagusPostoperationVitamin deficiencyPathogeny(发病机制)Paraesophagealfat layer

31、fuzzy,disappear.Anatomy of the EsophagusOn a widened upper segment with fluid levelOn a widened upper segment with fluid levelAnatomy of the EsophagusThe esophagus is a muscular tube, which is a digestive organ between the throat and stomach.Enhanced scanningT1W enhance scanning shows a lump in the

32、trachea and be enhanced like the carcinoma.There is a synechia(黏连) between the cancer and the aortic arch.NitrosamineEsophageal varicesAnatomy of the EsophagusPostoperationParaesophagealfat layerfuzzy,disappear.On a widened upper segment with fluid levelFungus(真菌)The middle segmentPostoperationM,63Y

33、, Progressivedysphagia20dT1W enhance scanning shows a lump in the trachea and be enhanced like the carcinoma.Without mucosal fold break.Achalasia of cardia and esophagus(食管贲门失弛缓征)Early stageT2WIThe fat layer disappeared and the wall of trachea be damaged.Beadedfilling defect(串珠样充盈缺损)Pathogeny(发病机制)U

34、lcerative carcinomaEnhanced scanningEnhanced CT scanshowed vascular tortuositygroup remarkable enhancement and delayedenhancement.Fungus(真菌)Magnetic Resonance Imaging(MR)Leiomyoma of the esophagus(食管平滑肌瘤)Anatomy of the EsophagusConstrictive typeTracheal bifurcation (气管分叉)On a widened upper segment w

35、ith fluid levelPeripheralorgan got involvedorlymph node metastasis.Beadedfilling defect(串珠样充盈缺损)广泛侵犯食管全层,形成腔外肿物，管腔狭窄，表面可见溃疡When the tumorinvadethe trachea , tracheoesophageal fistula(气管食管瘘)Smallnodules(小结节)Limiting filling defect(局限性充盈缺损)T1W enhance scanning shows a lump in the trachea and be enhanc

36、ed like the carcinoma.Leiomyoma of the esophagus(食管平滑肌瘤)Anatomy of the EsophagusPrevalence and mortalityIn early stageOn a widened upper segment with fluid levelT1W enhance scanning shows a lump in the trachea and be enhanced like the carcinoma.Enhanced CT scanshowed vascular tortuositygroup remarka

37、ble enhancement and delayedenhancement.Enhanced CT scanshowed vascular tortuositygroup remarkable enhancement and delayedenhancement.Enhanced CT scanshowed vascular tortuositygroup remarkable enhancement and delayedenhancement.On a widened upper segment with fluid levelThe upper segmentCancer invade

38、 the tracheaDietary habitsT2WIThe fat layer disappeared and the wall of trachea be damaged.3 Sections of the esophagus（Carcinoma occur most frequent）Without mucosal fold break.Anatomy of the EsophagusAnatomy of the EsophagusEnhanced CT scanshowed vascular tortuositygroup remarkable enhancement and d

39、elayedenhancement.Without mucosal fold break.On a widened upper segment with fluid levelAn expand over the tumorEnhanced scanning showedmild enhancement oftumor.In the middle and advanced stageLeiomyoma of the esophagus(食道平滑肌瘤).On a widened upper segment with fluid levelT2WIThe fat layer disappeared

40、 and the wall of trachea be damaged.Carcinoma of the esophagus is a common malignant tumor that occurs in a population cover 40 years old ,and in predilection for male(好发于男性).Leiomyoma of the esophagus(食道平滑肌瘤).NitrosamineDietary habits广泛侵犯食管全层,形成腔外肿物，管腔狭窄，表面可见溃疡The middle segmentM,63Y, Progressivedy

41、sphagia20dParaesophagealfat layerfuzzy,disappear.PostoperationPostoperationPrevalence and mortalityWithout mucosal fold break.Peripheralorgan got involvedorlymph node metastasis.T1W enhance scanning shows a lump in the trachea and be enhanced like the carcinoma.Limiting filling defect(局限性充盈缺损)Limiti

42、ng filling defect(局限性充盈缺损)Can u remember the 3 physiological stenosis of esophagus? (In this question u can answer it in Chinese)Leiomyoma of the esophagus(食道平滑肌瘤).Clinical featureThe surrounding of the tumor become bulged , and the folds of mucous become damaged.Carcinoma of the esophagus is a comm

43、on malignant tumor that occurs in a population cover 40 years old ,and in predilection for male(好发于男性).Middle and advanced stageOn a widened upper segment with fluid levelOn a widened upper segment with fluid levelAnatomy of the EsophagusIn early stageWhen the tumorinvadethe trachea , tracheoesophag

44、eal fistula(气管食管瘘)Clinical featureComputed Tomography(CT)Anatomy of the EsophagusCan u remember the 3 physiological stenosis of esophagus? (In this question u can answer it in Chinese)Carcinoma of the esophagus is a common malignant tumor that occurs in a population cover 40 years old ,and in predil

45、ection for male(好发于男性).The lower segmentFirst: The junction of the pharynx(咽) and esophagus.（Carcinoma occur most frequent）Medullary type(髓质型)Peripheralorgan got involvedorlymph node metastasis.Tracheal bifurcation (气管分叉)Anatomy of the EsophagusEnhanced scanningOn a widened upper segment with fluid levelLeiomyoma of the esophagus(食道平滑肌瘤).Tracheal bifurcation (气管分叉)Computed Tomography(CT)Can u remember the 3 physiological stenosis of esop