Chebulagic-acid - Phenol - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEChebulagic acidCat. No.: HY-N1996CAS No.: 23094-71-5分式: CHO分量: 954.66作靶点: Others作通路: Others储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 100 mg/mL (104.75 mM; Need ultrasonic)Mass Solvent

2、1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.0475 mL 5.2375 mL 10.4749 mL5 mM 0.2095 mL 1.0475 mL 2.0950 mL10 mM 0.1047 mL 0.5237 mL 1.0475 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制

3、终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 0.83 mg/mL (0.87 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 0.83 mg/mL (0.87 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 0.83 mg/mL (0.87 mM); Clear solution1/2 Ma

4、ster of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 Chebulagic acid个从果实中提取出来的COX-LOX双重 抑制剂。有抗炎和抗感染的效果。REFERENCES1. Kim HJ et al. Neuroprotective Effect of Chebulagic Acid via Autophagy Induction in SH-SY5Y Cells.Biomol Ther (Seoul). 2014Jul;22(4):275-81.2. Liu Y et al. Chebulagic acid

5、inhibits the LPS-induced expression of TNF- and IL-1 in endothelial cells by suppressing MAPKactivation. Exp Ther Med. 2015 Jul;10(1):263-268.3. Athira AP et al. Inhibition of Angiogenesis In Vitro by Chebulagic Acid: A COX-LOX Dual Inhibitor. Int J Vasc Med. 2013;2013:843897.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-