Voglibose-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEVogliboseCat. No.: HY-B0025CAS No.: 83480-29-9分式: CHNO分量: 267.28作靶点: Others作通路: Others储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 H2O : 200 mg/mL (748.28 mM)* means soluble, but saturation unk

2、nown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 3.7414 mL 18.7070 mL 37.4139 mL5 mM 0.7483 mL 3.7414 mL 7.4828 mL10 mM 0.3741 mL 1.8707 mL 3.7414 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Voglibosevaliolamine的衍物，能很好的抑制-葡萄糖苷酶，可作于糖症等。REFERENCES1. Chen, X., Y. Zheng,

3、and Y. Shen, Voglibose (Basen, AO-128), one of the most important alpha-glucosidase inhibitors. Curr Med Chem,2006. 13(1): p. 109-16.1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE2. Ikenoue, T., et al., Effect of a new hypoglycemic agent, A-4166 (-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phen

4、ylalanine, onpostprandial blood glucose excursion: comparison with voglibose and glibenclamide. Biol Pharm Bull, 1997. 20(4): p. 354-9.3. Moritoh, Y., K. Takeuchi, and M. Hazama, Combination treatment with alogliptin and voglibose increases active GLP-1 circulation,prevents the development of diabetes and preserves pancreatic beta-cells in prediabetic db/db mice. Diabetes Obes Metab, 2010. 12(3): p.224-33.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>