脑脊液浆膜腔积液检查

1、脑脊液浆膜腔积液检查OutlineCSF: colourless liquid that flows through the four cerebral ventricles, subarachnoid space and spinal canal surrounding the brain and spinal cord .CSF cirlulation communicate with blood circulationAdult:90150mlNewborn:10 60mlblood brain barrier AIMS中枢神经感染性疾病的诊断与鉴别诊断。脑血管疾病的诊断与鉴别诊断。协助

2、脑部肿瘤的诊断。中枢神经系统疾病的治疗与疗效观察。Contents of examinationGeneral Properties：pressure、color、 Transparency 、 Clots and filmChemical Examination： protein、glucose、chloride Microscopy Bacteriological Examination Pressure General Properties Adult(lying): 80180mmH2O， 40-50 drips/min children：40-100mmH2O。Increase：In

3、tracranial Inflammation：meningitis, cephalitis, myelitiscerebral edema, cerebral hemorrhage, brain tumorsExtracranial：hypertension, congestive heart failureDecrease:CSF circulation obstruction, loss or impairment in secretionColor changesColor of CSFConditions or causesClear, colorlessnormalMilky Wi

4、th WBC increasePink to yellowWith bloodYellowHyperbilirubinemiaProtein1.5g/LGreen Purulent CSFBrown to BlackMeningeal melanomaTransparency Normal :Clear, colorlessClear or Cloudy：Viral Meningitis、Epidemic Encephalitis B or Syphilis in CNSGround glass opacity：Tuberculous MeningitisMilky turbid：Purule

5、nt Meningitis Clots and filmNormal: No clots or film in 24 hoursPurulent Meningitis :clots observed in 1-2 hoursTuberculous Meningitis :thin film cover after 1224 hoursSubarachnoid obstruction:yellow jellyProtein Qualitative ：Pandy test：-/Quantitative ：0.45g/L (adult,lumbar puncture)+Chemical examin

6、ationClinical significanceinflammation：PM:TM:VM:Hemorrhage in cranial or subarachnoidintracranial mass lesions ：tumor, hematomamultiple sclerosis, neurosyphilisGlucose in CSFNormal value:GCSF/GP：0.30.9 Clinical significanceInflammation ：PM:TM: VM：normalIntracranial tumor, neurosyphilisHypoglycemia C

7、hloride in CSFAdult ：120130mmol/L TM：，102mmol/LPM：102116mmol/L。Hypochloremia，such as severe vomit、diarrhea, dehydrationNormal ValueRBC：noneWBC:adult：08106/L child：015106/L Microscopic ExaminationClinical SignificanceInfectious Diseases in CNSPURULENT MENINGITIS1000-2000 106/L ，segmented neutrocyte T

8、uberculous Meningitis 500 106/L，segment neutrocytes in early stage, and lymphocytes increase afterward, plasmocyte also observedViral Meningitis1000106/L，lymphocytesClinical SignificanceBrain tumor：lymphocytes and tumor cellsParasitic encephalopathy :eosinophile granulocyte Hemorrhage: RBCNORMALPMTM

9、VMSAHPressure mmH2O 70-180 或 Appearance Clear, colorless Milky 、greenGround Glass opacityclearbloodyClots and filmnoclotsThin film No jellyprotein 0.2-0.4g Glucose mmol/L2.5-4.5 Normal Chloride mmol/L 119-129 NormalNormalCells No neutrocytes Neutrocytes, lymphocytes and plasma cellslymphocytes RBC B

10、ACTERIALS NO pyogenic tubercle bacillusNo noGeneral conceptsserous membrane fluid:pleural effussionperitoneum serouspericardial effusion Serous Membrane Fluid Classification Transudate: non-inflammatoryExudate：inflammatorydifferential diagnosis of transudate or exudateTransudateExudatecausesIncreased capillary permeabilityInfection, malignant cancerAppearanceLight yellow, clear or cloudyBloody, purulent, milky turbidgravity1.018clotting-+Cells10