BiochemistryandMolecularBiology

1、Biochemistry and Molecular BiologyProfessor Junming GUO, M.D., Ph. D. Office: Room 305, Zhizhen Building Laboratory: Room 304, Zhizhen Building Tel: 87600758 Biochemistry and Molecular Biology Biochemistry is the study of the structures and interactions of biological molecules. Modern biochemistry n

2、ow plays a central role in understanding of events at the molecular level. Biochemistry and Molecular Biology is one subject.What is Biochemistry?Proteins（蛋白质）Nucleic acid（核酸）Fats （脂类）Sugars （糖类）Biochemistry is the study of molecules found in living organisms.Biochemists study molecules such asVitam

3、ins（维生素）Hormones（激素）Minerals（矿物质）And many others.Biochemistry is an experimental science (Toys!).Why study Biochemistry?The biochemist has a knowledge of how life forms work at the molecular level!Applications of this knowledge:Understand the molecular basis of diseasesDetection of biological molecu

4、les (e.g. mad cow, steroids)Developpment of new cures (e.g. vaccine development)Biotechnology: use of organisms to clean the environmentBECAUSE ITS COOL AND ITS FUN!Biochemistry is a multidisciplinary scienceBiochemistryChemistryBiologyGeneticsMolecular BiologyBiotechnologyPharmacologyCellular Biolo

5、gyBut: is it chemistry?YES:Study of moleculesStructure/ReactionUse of common methods (e.g. chromatography)NO:Deals with molecules in living organismsKnowledge of biology is very importantNew methods adapted to living organisms (e.g. genetic engineering)Tools of BiochemistryGenetic engineering(DNA cl

6、oning, etc)Cancer cell cultureAnimalsMicroscopyBioinformaticsProtein isolationand characterisationMicrobiologyChemical methodsPhysical methodsRadioactivityImportant of Biochemistry and Molecular Biology:* 专业基础必修课* 医学主干课程* 医师资格考试必考内容How to learn Biochemistry and Molecular Biology？ Biochemistry Biolog

7、y + Chemistry Emphases = concept (概念) + significant(意义)References（参考资料） （一）教材1 Instant Notes in Biochemistry(Second Edition), Hames B.D. and Hooper N.M.，BIOS Scientific Publishers Limited, UK (科学出版社影印版 2004) 2 Instant Notes in Molecular Biology(Second Edition), Turner P.C., et al., BIOS Scientific Publishers Limited, UK (科学出版社影印版 2003)3 生物化学与分子生物学（厉朝龙，中国医药科技出版社）； 4 生物化学 （第六版；人民卫生出版社）；5 Principles of Biochemistry (Lehninger Biocehmistry)6人体基因学 （郭俊明，浙江科技出版社） （二）复习资料1 生物化学复习纲要和练习 浙江大学出版社2 医学专业必