Fedovapagon-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEFedovapagonCat. No.: HY-14887CAS No.: 347887-36-9分式: CHNO分量: 462.58作靶点: Others作通路: Others储存式: 4C, stored under nitrogen* In solvent : -80C, 6 months; -20C, 1 month (stored undernitrogen)溶解性数据体外实验 DMSO : 125 mg/mL (270.22 mM)* me

2、ans soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.1618 mL 10.8089 mL 21.6179 mL5 mM 0.4324 mL 2.1618 mL 4.3236 mL10 mM 0.2162 mL 1.0809 mL 2.1618 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液

3、，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (4.50 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (4.50 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolub

4、ility: 2.08 mg/mL (4.50 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 Fedovapagon种选择性的加压素 V2R 激动剂，EC50 值为 24 nM。被开发于夜尿症 1。IC50 & Target EC50：24 nM (V2R) 1REFERENCES1. Yea CM, et al. New benzylureas as a novel series of potent, nonpeptidic vasopressin V2 receptor agonists. J Med Chem. 2008 Dec25;51(24):8124-34.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fa