Felodipine _Calcium Channel 抑制剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEFelodipineCat. No.: HY-B0309CAS No.: 72509-76-3分式: CHClNO分量: 384.25作靶点: Calcium Channel; Autophagy作通路: Membrane Transporter/Ion Channel; Neuronal Signaling;Autophagy储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C

2、1 month溶解性数据体外实验 DMSO : 100 mg/mL (260.25 mM; Need ultrasonic)H2O : 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (6.51 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (6.51 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活

3、性 Felodipine长效的钙离通道阻断剂。户使本产品发表的科研献 Int J Pharm. 2017 Jan 30;517(1-2):19-24.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Johnson, J.D. and D.A. Fugman, Calcium and calmodulin antagonists binding to calmodulin and relaxation of coronary segments. JPharmacol Exp Ther, 1983. 226

4、(2): p. 330-4.2. Rodler, S., et al., Ca(2+)-channel blockers modulate the expression of interleukin-6 and interleukin-8 genes in human vascular smoothmuscle cells. J Mol Cell Cardiol, 1995. 27(10): p. 2295-302.3. Yiu, S. and E.E. Knaus, Synthesis, biological evaluation, calcium channel antagonist activity, and anticonvulsant activity of felodipinecoupled to a dihydropyridine-pyridinium salt redox chemical delivery system. J Med Chem, 1996. 39(23): p. 4576-82.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-589559