Sucrose-D-plus-Saccharose-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESucroseCat. No.: HY-B1779CAS No.: 57-50-1Synonyms: D-(+)-Saccharose分式: CHO分量: 342.3作靶点: Others作通路: Others储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 H2O : 100 mg/mL (292.14 mM; Need ultrasonic

2、 and warming)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.9214 mL 14.6071 mL 29.2141 mL5 mM 0.5843 mL 2.9214 mL 5.8428 mL10 mM 0.2921 mL 1.4607 mL 2.9214 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Sucrose由两种单糖，葡萄糖和果糖组成的糖。体内研究Sucrose is a disaccharide which is compos

3、ed of two monosaccharides, glucose and fructose. Compare tochow-feeding, high-energy (HE)-feeding results in an overall decreased preference for Sucrose solutions inboth strains. Specifically, obesity-prone (OP) rats prefer 0.3 M and 1.0 M Sucrose solutions less during HE-feeding relative to chow-fe

4、eding (P=0.046 and P=0.012, respectively). As well, obesity-resistant (OR) rats1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEexhibit decreased preferences for 0.01 M, 0.03 M, and 1.0 M Sucrose when HE-fed compare to chow-fedcounterparts (P 1.PROTOCOLAnimal A total of 66 male 8-wk-old Sprague-Dawl

5、ey obesity-prone (OP) and obesity-resistant (OR) rats (n = 38 perAdministration 1 each phenotype), weighing 275 g and 210 g respectively, are used in this study. After recovery and attainingpre-surgical weights, rats undergo three training trials of 60-min sham feeding sessions with 0.03 M Sucroseso

6、lution. During testing, rats are briefly deprived of water (0900 to 1600 h) but not food, and are tested for 1 h(1400 to1500 h) sham intake of 0.03 M Sucrose solution until a stable baseline is achieved. Afterwards, ratsare sham fed one of three Sucrose solutions (0.03, 0.3, and 1.0 M) in random ord

7、er, every other day, witheach concentration tested at least twice. Sucrose intake is individually recorded every 5 min for 60 min 1.MCE has not independently confirmed the accuracy of these methods. They are for reference only.REFERENCES1. Duca FA, et al. Effect of diet on preference and intake of sucrose in obese prone and resistant rats. PLoS One. 2014 Oct20;9(10):e111232.McePdfHeightCaution: Product has not been fully validated for medical applications.For resear