化妆品卫生规范(2007版)化妆品组分中限用防腐剂

1、精品文档表4化妆品组分中限用防腐剂(按INCI名称英文字母顺序排列)序号物质名称化妆品中大允许使用浓 度使用范围和限制条件标签上必须标印的使用条件和注意事项中文名称英文名称INCI名称12-漠-2-硝基丙烷-1,3二醇Bronopol (INN)2-Bromo-2-nitropropane-1,3-diol0.1%避免形成亚硝胺25-漠-5-硝基-1,3-二嗯烷5-Bromo-5-nitro-1,3-dioxane5-Bromo-5-nitro-1,3-dioxane0.1%仅用于淋洗类产品；避 免形成亚硝胺37-乙基二环嗯建琳5-Ethyl-3,7-dioxa-1-azabicyclo3.3

2、.0octane7-Ethylbicyclooxazolidine0.3%禁用于口腔卫生产品和 接触粘膜的产品4烷基(C12-C22)三甲基镂漠化物或氯化物(2)Alkyl(C 12-C22) trimethyl ammonium, bromide and chlorideAlkyl(C 12G2) trimonium bromide and chloride0.1%5苯扎氯镂,苯扎漠镂, 苯扎糖精镂Benzalkonium chloride, bromide andsaccharinateBenzalkonium chloride, bromide and saccharinate0.1%(

3、以苯扎氯镂计)避免接触眼睛6士索氯镂Benzethonium chlorideBenzethonium chloride0.1%(1)淋洗类产品(2)口腔卫生用品之外的驻留类产品7苯甲酸及其盐类和酯类(2)Benzoic acid, its salts and estersBenzoic acid, its salts and esters0.5%(以酸计)8苯甲醇Benzyl alcoholBenzyl alcohol1.0%9甲醛苇醇半缩醛BenzylhemiformalBenzylhemiformal0.15%仅用于淋洗类产品10漠氯芬6,6-Dibromo-4,4-dichloro-

4、2,2 -methylene-diphenolBromochlorophen0.1%11氯已定及其二葡萄糖酸 盐，二醋酸盐和二盐酸 盐Chlorhexidine (INN) and its digluconate,diacetate and dihydrochlorideChlorhexidine and its digluconate, diacetate and dihydrochloride0.3%(以氯己定表示)12氯乙酰胺2-ChloroacetamideChloroacetamide0.3%含氯乙酰胺13三氯叔丁醇Chlorobutanol (INN)Chlorobutanol0.

5、5%禁用于喷雾产品含三氯叔丁醇14正氯酚2-Benzyl-4-chlorophenolChlorophene0.2%15氯二甲酚4-Chloro-3,5-xylenolChloroxylenol0.5%16氯苯甘醴3-(p-chlorophenoxy)-propane-1,2diolChlorphenesin0.3%序号物质名称化妆品中大允许使用浓度使用范围和限制条件标签上必须标印的使用条件和注意事项中文名称英文名称INCI名称17氯咪巴唾1-(4-chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-oneClimbazole0.5%18脱

6、氢醋酸及其盐类3-Acetyl-6-methylpyran-2,4Dehydroacetic acid0.6%（以酸计）禁用于喷雾产品(3H)-dione and its salts19双（羟甲基）咪座烷基月尿N-(Hydroxymethyl)- N-(dihydroxy methyl-1,3-dioxo-2,5-imidazolinid yl-4)- N -(hydroxymethyl) ureaDiazolidinyl urea0.5%20二漠己眯及其盐类，包 括二漠已眯羟乙磺酸盐3,3 -Dibromo- 4,4 -hexamethylene dioxydibenzamidine and

7、 its salts (including isethionate)Dibromohexamidine and itssalts, includingdibromohexamidine isethionate0.1%21二氯苯甲醇2,4-Dichlorobenzyl alcoholDichlorobenzyl alcohol0.15%22二甲基嗯唾烷4,4-Dimethyl-1,3-oxazolidineDimethyl oxazolidine0.1%终产品的pH不得低于623DMDM乙内酰月尿1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2

8、,4-dioneDMDM hydantoin0.6%24甲醛和多聚甲醛（2）Formaldehyde and paraformaldehydeFormaldehyde and paraformaldehyde0.2%（口腔卫生产品除外）0.1%（口腔卫生产品）（以游离甲醛计）禁用于喷雾产品25甲酸及其钠盐Formic acid and its sodium saltFormic acid and its sodium salt0.5%（以酸计）26戊二醛Glutaraldehyde (Pentane-1,5-dial)Glutaral0.1%禁用于喷雾产品含戊二醛（当成品中 戊二醛浓度超过0.

9、05% 时）27己眯定及其盐，包括己 眯定二个羟乙基磺酸盐 和己眯定对羟基苯甲酸 盐1,6-Di(4-amidinophenoxy)- n-hexa ne and its salts (including isethionate and p -hydroxybenzoate)Hexamidine and its salts, including hexamidine diisethionate and hexamidine paraben0.1%28海克替咤Hexetidine (INN)Hexetidine0.1%29咪唾烷基月尿3,3 -Bis(1-hydroxymethyl-2,5-di

10、o xoimidazolidin-4-yl)- 1,1 -methyle nediureaImidazolidinyl urea0.6%30无机亚硫酸盐类和亚硫酸氢盐类Inorganic sulphites andhydrogensulphitesInorganic sulfites and hydrogensulfites0.2%（以游离SO2计）序号物质名称化妆品中大允许使用浓使用范围和限制条件标签上必须标印的中文名称英文名称INCI名称度使用条件和注意事项31碘丙焕醇丁基氨甲酸酯3-Iodo-2-propynylbutylcarbamateIodopropynyl butylcarbam

11、ate0.05%不能用于口腔卫生和唇部产品用后存留在皮肤上 的产品，当其浓度超 过0.02%时，需注明如下警示语：含碘32乌洛托品Hexamethylenetetramine (INN)Methenamine0.15%33甲基二漠戊二睛1,2-Dibromo-2,4-dicyanobutaneMethyldibromo glutaronitrile0.1%仅用于淋洗类产品34甲基异曝座啾酮2-Methylisothiazol-3(2 H)-oneMethylisothiazolinone0.01%35甲基氯异曝晚琳酮和甲 基异曝座琳酮与氯化镁 及硝酸镁的混合物Mixture of5-chlor

12、o-2-methylisothiazol-3(2 H)-one and2-methylisothiazol-3(2 H)-one with magnesium chloride and magnesium nitrateMixture ofmethylchloroisothiazolinone and methylisothiazolinone with magnesium chloride and magnesium nitrate0.0015%（以甲基氯异曝座 啾酮和甲基异曝座啾酮为3: 1的混合物计）36o-伞花烧-5-醇4-Isopropyl- m-cresolo-Cymen-5-ol

13、0.1%37。-苯基苯酚Biphenyl-2-ol and its saltso-Phenylphenol0.2%(以苯酚计)384-羟基苯甲酸及其盐类和酯类4-Hydroxybenzoic acid and its salts and esters4-Hydroxybenzoic acid and its salts and esters单一酯：0.4%(以酸计)混 合酯：0.8%(以酸计)39p-氯-m甲酚4-Chloro-m-cresolp-Chloro- m-cresol0.2%禁用于接触粘膜的产品40苯氧乙醇2-PhenoxyethanolPhenoxyethanol1.0%41苯氧

14、异丙醇(2)1-Phenoxypropan-2-olPhenoxyisopropanol1.0%仅用于淋洗类产品42叱罗克酮乙醇胺盐1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon and itsPiroctone olamine(a) 1.0%(b) 0.5%(a)淋洗类产品(b)其它产品monoethanolamine salt43盐酸聚氨丙基双服Poly(l-hexamethylenebiguanide)hydrochloridePolyaminopropyl biguanide hydrochloride0.3%44丙酸及其盐类P

15、ropionic acid and its saltsPropionic acid and its salts2%（以酸计）45聚季镂盐-15Methenamine3-chloroallylochloride (INNM)Quaternium-150.2%46水杨酸及其盐类,2）Salicylic acid and its saltsSalicylic acid and its salts0.5%（以酸计）除香波外，不得用于三 岁以下儿童使用的产品中三岁以下儿童勿用序号物质名称化妆品中大允许使用浓度使用范围和限制条件标签上必须标印的使用条件和注意事项中文名称英文名称INCI名称47苯汞的盐类，

16、包括硼酸苯汞Phenylmercuric salts (including borate)Salts of phenylmercury, including borate0.007%（以 Hg计），如果 同本规范中其它汞化合物混合，Hg的大浓度仍为仅用于眼部化妆品和眼部卸妆品含苯汞化合物0.007%48沉积在二氧化钛上的氯化银Silver chloride deposited on titanium dioxideSilver chloride deposited on titanium dioxide0.004%(以 AgCl 计)沉积在TiO2上的20%(w/w) AgCl,禁用 于三岁以

17、下儿童使用的 产品、口腔卫生产品以 及眼周和唇部产品49羟甲基甘氨酸钠Sodium hydroxymethylamino acetateSodiumhydroxymethylglycinate0.5%50碘酸钠Sodium iodateSodium iodate0.1%仅用于淋洗类产品51山梨酸及其盐类Sorbic acid (hexa-2,4-dienoic acid) and its saltsSorbic acid and its salts0.6%(以酸计)52硫柳汞Thiomersal (INN)Thimerosal0.007%(以 Hg计)，如果 同本规范中其它汞化合物混合，Hg的

18、大浓度仍为0.007%仅用于眼部化妆品和眼部卸妆品含硫柳汞53三氯卡班Triclocarban (INN)Triclocarban0.2%纯度标准：3,3 ,4-和氯偶氮苯少于1mg/kg;3,3 ,4,四氯氧化偶氮苯少于1mg/kg54三氯生Triclosan (INN)Triclosan0.3%55十一烯酸及其盐类Undec-10-enoic acid and saltsUndecylenic acid and salts0.2%(以酸计)56叱硫翁锌(2 )Pyrithione zinc (INN)Zinc pyrithione0.5%可用于淋洗类产品，禁用于口腔卫生产品(1) a表中所列防腐剂均为加入化妆品中以抑制微生物在该化妆品中生长为目的的物质。b化妆品