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1、Analytical ChemistryElectrophoresisJournal of chromatography (A) (B)Journal of Agricultural and Food ChemistryJournal of Separation ScienceTanataAnalytstAnal BiochemAnal Chim Acta Anal Bioanal ChemJournal of Pharmaceutical and Biomedical AnalysisAnalytical LettersJournal of ChemometricsAnalytical sc

2、iencesPlanta medicaJournal of EthnopharmacologyPhytochemical analysisChromatographiaChemical & Pharmaceutical BulletinActa Chimica SinicaFood ChemistryFunctional Food Materials & Methods Results Abstract Introduction Discussion &Conclusion Where do I start?Fig. 2 Effect of pH on resolution of nucleo

3、sides. Conditions: pressure injection, 566 kPa for 6s; 57 cm 75 m mm column (untreated fused-silica; Beckman); running buffer, 0.2 M boric acid-sodium hydroxide. UV detection at 254nm. Temperature, 25; voltage 25 kV. A, adenoside; G, guanoside; U, uridine. Numbers indicate pH 7.5, 8.5, and 9.5, resp

4、ectively. Graphical AbstractHONOHOHHOHHHHO145197911121314161718202122242728Puqienine F, a Novel Veratramine Alkaloid from the Bulbs of Fritillaria puqiensisHui-Jun LI, Yan JIANG, Ping LI, and Wen-Cai YEGraphical AbstractPoints of grammar to keep in mind:Dear Sir,We would like to submit the manuscrip

5、t entitled “New steroidal alkaloids from the bulbs of Fritillaria puqiensis”, which we wish to be considered for publication in your journal. On behalf of all the authors, I herein confirm that neither the entire paper nor any part of its content has been published or has been accepted elsewhere, an

6、d it is not being submitted to any other journal. An exampleWe believe that two aspects of this manuscript will make it interesting to the readers of your journal. First, we describe, for the first time, six structurally novel steroidal alkaloids found in the genus Fritillaria. Second, this finding,

7、 together with our very recent article (J Nat Prod, 2005, 68, 264-267.), provide the chemotaxonomical evidence for treating the species F. puqiensis as a specific rank instead of a subspecies of F. thunbergii.Besides, we request that our manuscript would be edited for grammar at the same time as the

8、 scientific review.Correspondence and questions about the paper should be directed to Prof. Ping Li at the following address, phone and fax number, and e-mail address:An exampleDear Prof. xxx (Editor):Attached please find the PDF version of my paper entitled xxx with the kind request to consider it

9、for publication in your journal xxx.The authors claim that none of the material in the paper has been published oris under consideration for publication elsewhere.Should you receive the paper, please send me a e-mail to confirm receiptof it.Thanks a lot in advance!Sincerely, yoursXxx Who qualify?Edi

10、torial staff Board of Reviewing EditorsREJECTREVIEWREJECT70%ACCEPT (10%)70%20%10%20-30%Dear Dr. Li, The Editors and reviewers have completed their review of your manuscript, New steroidal alkaloids from the bulbs of Fritillaria puqiensis. We feel that it is not acceptable in its present form for pub

11、lication in Steroids. While the Editors and reviewers agree that the manuscript has merit, there are several important criticisms that must be met for it to be acceptable. These require a detailed response from you to the Editors and/or additional data or experiments. We include the detailed comment

12、s of the reviewers to illustrate the basis for our decision and to assist you in preparing a revised manuscript. It is likely that more work will be required as the comments indicate. The Editors will further consider a manuscript revised to meet the comments. . If the revised manuscript is not rece

13、ived within six months of the above date, it will be considered withdrawn. Thank you for giving us the opportunity to review your work. Sincerely, William Rosner, MD Richard B. Hochberg, PhD Dear Editor,Thank you very much for your letter of April 14, 2006, with regard to our manuscript (STEROIDS-D-

14、06-00022). I am sending herein our revised manuscript.As the two reviewers suggested, we reorganized our manuscript. The correctness has been marked in red in the revised manuscript and our incorporation of the reviewers comments is as follows:Reviewer #1Question 1. NMR signal assignments: a) The 13

15、C NMR signal assignments for C-16 and C-23 of compound 6 appear to be reversed, together with the corresponding 1H NMR assignments. Answer 1: We accepted the second reviewers suggestion to do H-H COSY experiments of all six compounds, and checked the overall assignments of the isolates by a combinat

16、ion of HMQC and HMBC. Dear Dr. Li,The Editors and reviewers have completed their review of your manuscript, New steroidal alkaloids from the bulbs of Fritillaria puqiensis.We are pleased to inform you that, pending revision, it is acceptable for publication in Steroids. The reviewers have made sugge

17、stions for revision, and the Editors believe their constructive criticism merits your consideration. The critiques are included below to guide you in the preparation of a fully acceptable manuscript. We look forward to the prompt return and publication of your appropriately modified manuscript. Sincerely,William Rosner, MDRichard B. Hochberg, PhD Dear editor,We are so happy to hear that our manuscript is acceptable for publication in your journal. We prepare our manuscript in li

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