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1、Abstract Telemedicine systems have become an important supporting for the medical staffs. As the development of the mobile phones, it is possible to apply the mobile phones to be a part of telemedicine systems. We developed an innovative Remote Patient Monitoring System using a Java-enabled 3G mobil

2、e phone. By using this system, doctors can monitor the vital biosignals of patients in ICU/CCU, such as ECG, RESP, SpO 2, EtCO2 and so on by using the real-time waveform and data monitoring and list trend data monitoring functions of installed Java jiglet application on the mobile phone. Futhermore,

3、 doctors can check the patients' information by using the patient information checking function. The 3G mobile phone used has the ability to implement the application as the same time as being used to mak a voice call. Therefore, the doctor can get more and more information both from the browsin

4、g the screen of the mobile phone and the communicating with the medical staffs who are beside the patients and the monitors. The system can be conducted to evaluate the diagnostic accuracy, efficiency, and safety of telediagnosis.I. I NTRODUCTIONHE rapid development of information and telecommunicat

5、ion technology has brought great revolutions in our everyday lives. The impact to medical field is being felt with many new applications using these technologies. Telemedicine is essentially the use of both information technology and telecommunications to provide health services or support health se

6、rvice provision over a distance. Telemedicine systems can be devided into two fields: one is that the mobile devices are used by patients to measure the medical data of themselves. For example, the European EPI-MEDICS project has developed a Personal ECG Monitor having the capabilities of recording

7、ECG at anywhere and anytime 2. A Peak flow monitoring system via a mobile phone for asthma is developed in UK5. The other field is that the mobile devices are used by medical staffs as an assistant for their daily work. A paramedical system has been developed using PDA to get efficient medical infor

8、mation in India1.TDuring the past decade, several new kinds of mobile devices, such as PDA, mobile phones and some intelligentPu Zhang, Yuichi Kogure, Hiroki Matsuoka, Masatake Akutagawa, Yohsuke Kinouchi are with the Institute of Technology and Science, the University of Tokushima, Tokushima, 770-8

9、506, JAPAN. (corresponding author to provide phone: +81-88-656-7576; e-mail: zhangpuee.tokushima-u.ac.jpQinyu Zhang is with ShenZhen Graduate School of Harbin Institute of Technology, ShenZhen, Chinaand wearable medical devices have been designed. Combined to the recent proliferation of wireless com

10、munication solutions, this provides new development opportunities for telemedicine. However, there are some inherent limitations of mobile devices, such as memory capacity, CPU speed, small screen area, etc. These make internet access from mobile devices more difficult as compared to that from deskt

11、op computers.In Japan, mobile phone is recognized as “Ubiquitous service platform”. The total number of the subscribers of mobile telephone(including PHS is about 95 million. The big market is shared by three carrier companies. More than 52 million users belong to NTT DoCoMo Inc., while over 27 mill

12、ion users belong to KDDI Corporation, and about 15 million users belong to SOFTBANK Corporation(as of January 31, 2007, according to Telecommunications Carriers Association, Japan. The statistic data mean that almost each person in Japan has a mobile phone in hand. In another aspect, the mobile phon

13、es have become more and more powerful. Although remain small screen size of the mobile terminals, the functions, such as memory capacity, CPU speed, Java-enabled applications and camera performance are continuously getting improved. Futhermore, third-generation(3G mobile communication networks(WCDMA

14、 combine standardized streaming with a range of unique services to provide high-quality Internet contents. The phone is possible to transfer large amount of data, such as photos, movies and application files etc, because of its wide transmission band.This paper presents a novel Remote Patient Monito

15、ring System for doctor. By using a 3G mobile phone, the doctor can monitor the realtime biosignals of patients in ICU/CCU through the screen of the mobile phone while making a voice call. The software developed on the mobile phone can realize three main monitoring functions, including realtime wavef

16、orm and data monitoring, list trend data monitoring and the patient information checking. The doctor can select which he wants to check using the keyboard of the mobile phone.The whole system has been implemented in the laboratory environment. The main function of the system, i.e., transferring the

17、waveform data and text data of patients to the doctor's mobile phone, has been successfully accomplished as well as other auxiliary functions.The goal of this study is to construct a new bridge between the medical staffs in hospital and the doctor using the mobile phone to discuss and diagnose t

18、he patients' state of illness as quickly and accurately as possible to saveA Remote Patient Monitoring System Using a Java-enabled 3GMobile PhonePu Zhang, Yuichi Kogure, Hiroki Matsuoka, Masatake Akutagawa, Yohsuke Kinouchi, Qinyu ZhangProceedings of the 29th Annual InternationalConference of th

19、e IEEE EMBSCité Internationale, Lyon, FranceAugust 23-26, 2007.FrP2D2.9patients' lives.II. S YSTEM ARCHITECTUREA. System OverviewThe overview of the Remote Patient Monitoring System is shown in Fig.1. The system is mainly composed of three parts:patients monitoring system, Remote Informatio

20、n Server built in hospital and a Java-enabled 3G mobile phone. They are connected by the Internet and 3G mobile networks. The patients monitoring system is composed of Bedside Monitor, Central Station Monitor and PC used by Medical staffs in hospital.Conventionally, several patients' information

21、 can be collected by the Bedside Monitors and stored in the Central Station Monitor. In the proposed system, the patients' information in the Central Station Monitor, including numeric signal data, text data and realtime waveform data can be extracted by the Remote Information Server and changed

22、 into the recognizable pattern for Java jiglet application on the mobile phone, by using a PHP web application. The 3G mobile phone used should carry multi-tasking function, such as using a Java based application during a voice call. Via the Internet and 3G mobile networks, the Java jiglet applicati

23、on on the mobile phone receives the data and displays the visual information on the screen of the mobile phone to the doctor.Fig.1: the overview of the systemB. Patients Monitoring SystemThe Bedside Monitor is called DS-7100 system while the Central Station Monitor is called DS-5700 system. They are

24、 both produced by Fukuda Denshi Company and being widely used in Japan.The Bedside Monitor can monitor patient's ECG, RESP, SpO 2, EtCO2, IBP, NIBP and TEMP. In the experimentation stage, we use the demonstration function of it to generate the biosignals we need for transmission.The Central Stat

25、ion Monitor stores data from Bedside Monitor. The upper limit of the capacity is up to storing 96 hours continuous waveform data.Medical staffs in hospital can also monitor the state of patients by using the PC which can access the Remote Information Server via the Local AreaNetworks in the hospital

26、.C. Remote Information ServerRemote Information Server is a web server, which is technically call an Apache server running on a SUSE Linux operating system. To create HTML pages dynamically, the PHP Hypertext Preprocessor(Apache Software Foundation, 2004 is used.Remote Information Server is the focu

27、s of the system's data transferring process. As is shown in Fig.2, the server can be accessed both from the 3G mobile phone and PC used by medical staffs in hospital.In the mobile phone's case, PHP application on the server get the requests from the mobile phone and access Central Station Mo

28、nitor to extract the specific data, such as patients' data, event data and alarm data. These data are translated to the form that can be recognized by the Java jiglet application of the mobile phone. Then the application creates a unit of vital data and sends it back to the mobile phone. In PC&#

29、39;s case, the medical staffs can access the server by using the web browser of the PC to get the data they need. D. The Java-enabled 3G mobile phoneWe use FOMA F901iC mobile phone released by NTT DoCoMo, Inc., which is Japan's biggest mobile communication carrier. The specification of it is sho

30、wn in Table I.TABLE IT HE SPECIFICA TION OF FOMA F901I C MOBILE PHONEApplication size100KByteScratchpad Size400KByteCommunication ProtocolHTTPType of ApplicationClient/Server modelDisplay SizeQVGA TFT(240*320Display output rate63 points/sThe networks between the Remote Information Server and the 3G

31、mobile phone is shown in Fig.3.Patients BedsideMonitorCentralStationMonitorRemoteInformationServerMedicalStaffsDoctor3G Mobile PhoneFig.3 the network structure between the remote information server and the 3G mobile phoneThe i-mode server is the connector of the Internet and the 3G mobile network. I

32、t is provided by NTT DoCoMo Inc. It can support high-speed packet data communication via 3G mobile networks. The Java jiglet application which is basedon the Java platform can be used not only on the NTT DoCoMo's mobile phones, but also can be used on other mobile phones released by the other tw

33、o carriers. It exchanges information with the Remote Information Server through the i-mode server. Anotherfunction of the Java jiglet application is to display the data the mobile phone got and create a interface between the doctor and mobilephone. III. APPLICATION DEMONSTRATIONThe Java jiglet appli

34、cation on the mobile phone can implement three functions. They are realtime waveform and data monitoring, list trend data monitoring and the patient information checking.A. Realtime Waveform and Data MonitoringRealtime waveform and data monitoring can monitor the patients' biosignals simultaneou

35、sly with about 20 seconds delay after the Bedside Monitor in hospital. The doctor can choose by pressing the mobile phone's keyboard which he would like to check. The original information can been seen in Fig. 4(a. And the menu that the doctor can select from the mobile phone is shown in Fig. 4(

36、b.Take ECG waveform for instance. By selecting the HR item in ECG1's submenu(the right column in the screen, approximately 6seconds waveform can be seen on the screen of the mobile phone, as is shown in Fig. 4(c. The bottom of the screen also shows the basic information of the waveform, includin

37、g the Patient ID, the name of the waveform, the time on the Bedside Monitor and the heart rate of the patient is 60, which is shown on the screen. Fig.4(a the screen of Bedside MonitorFig. 4(b The select submenu in realtime waveform and data monitoring functionFig.4(c the screen of realtime waveform

38、 and data monitoringB. List Trend Data MonitoringList trend data monitoring allows the doctor checking the patients' data of the last 4 days, as is shown in Fig.5. The data shown involve parameters of ECG, BP, SpO2 and so on. The data are taken on a trend of the changing of the parameters every

39、10 minutes. The doctor can select the time point in which he is interested. This function makes development of the patient's state of illness clear to the doctor and help the doctor to analyze and make the right decision. Fig.5 The screen of the list trend data monitoringC. Patient Information C

40、heckingThe patient information checking function displays the basic information of the patient, as is shown in Fig. 6. Because it is a demonstration, some parameters are the initial value of the Monitor.Fig.6 the screen of the patient information checkingIV . PERFORMANCE ANAL YSIS AND DISCUSSIONAfte

41、r the system was successfully implemented, some test has been done. One of the most important results is about the time used when the application is brought into practise. As mentioned in the last chapter, the delay for realtime waveform monitoring is about 20 seconds. The time used varied with diff

42、erent mobile phones. Take the NTT DoCoMo's FOMA F901iC for instance:1 As mentioned in the last chapter, the delay for realtime waveform monitoring is about 20 seconds. 2 The total time used for starting the application from the beginning on average is 17.3 seconds.3 Time for receiving realtime w

43、aveform on average is4.7 seconds.4 Time for receiving list trend data on average is 8.1 seconds.5 Time for receiving patient's information on average is 4.6 seconds.The transferring data rate is about 120kbps on average. This means it is fast enough to afford the realtime monitoring.On the other

44、 hand, someproblems need to be solved. When the mobile phone cannot be connected to the base stations because of being out of service area or other unknown reasons for even a few seconds, the realtime monitoring waveform data become too confusing to be distinguished. Anotherproblem is that the time

45、used for starting the application is long. The third one is that i-mode service cannot be used all over the world.V . CONCLUSIONS AND FUTURE WORKSIn this paper, we developed a novel Remote Patient Monitoring System for doctors to monitor the patients' biosignals in ICU/CCU on a Java-enabled 3G m

46、obile phone. By using this system, doctor can monitor patients' realtime data, list trend data and check the patients' information during a voice call from other medical staffs in hospital. It can help doctor with diagnosing the patients' situation more quickly and accurately.In the future, a Remote Patient Monitoring System will be developed by adopti

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