chap132 胺类化合物

1、rnh2rnhrrnrrr1nr4r3r2xr = 烷基：烷基： 脂肪胺脂肪胺 芳基：芳基： 芳香胺芳香胺cch3ch3h3cnh2cch3ch3h3cohnh2nhch3nh2ch2nh2ch3ch2-nh2ch3nhch2ch3nh2-ch2-ch2-nh2ch3ch2-nh-ch2ch3甲基甲基+乙基乙基+胺胺甲乙胺甲乙胺二乙基二乙基+胺胺二乙胺二乙胺甲基甲基+乙基乙基+异丙基异丙基+胺胺甲乙异丙胺甲乙异丙胺ch3chchch2ch3ch3nh2nnnhhhhhch3ch3ch3h3cnc2h5ch3hnc2h5ch3hnc2h5ch3c6h5ch2=chch2nc2h5ch3c6h5c

2、h2=chch2+nnch3ch3ch3nnch3nhhrxnh3rnh2+nh4x+rxrnhrrnrrrnrr+rxrcnh2, raney nirch2nh2lialh4nh3lialh4rconh2h2orch2nh2rcrnohh2 / nirchrnh2或 liah4rcrnnh2h2 / ninhookohor k2co3nookr xnoornh2nh2nh2r或或r otssch3ooorr otsrcnh2obr2 / naohrnh2+co2rxrnh+rnh2碱碱rhx ( (碱碱吸吸收收) )rcrnrh2 / nirchrnhrrcronh2rh+lialh4rco

3、nhrh2orch2nhr(1)(2)rxrnh+碱碱rhx ( (碱碱吸吸收收) )rnrrrnhrn-bulirnrrx醚醚lirnrrrchc(h)rnr2h2ch(h)rnr2pd / crch2c(h)rhnr2oh+rch2arno2arnh2还还原原剂剂fe / hcl ， sn / hcl ， sncl2 / hclh2 / ni or pt or pdh2s / nh4oharxarnh2xo2nr2nhno2nrrnanh2arnh2cox2 / naoharnh2+co2ooonhoonaohnh2ooonacl2 / naohnh2oonah+nh2oohnh3nnhh

4、nrrrrrhrnconnnh2nhnnhhrnhhhr2nhhr3n h ohhoh2oh2oh2oh2oh2nrrrhnh2ch3ch2nh2nh2no2nh2no2no2r nh2+ hclr nh3clr nh2+ hoso3hr nh3 oso3hrnh2 rnh3clrnh2 + h2o + naclhclnaohhclnh2cooch2ch2n(c2h5)2hclhclcooch2ch2n(c2h5)2nh2rnh2rxrrnh+r2nhrx+rr2n+hx+hxr3nrx+rr3n xrcrorcrnrrnh2+h+r2nhrch2crocrnrr+rchh+r3nrcro+n

5、o reaction+h2o+h2onh2+ ch3ohh2so4, 250oc25- 30atmn(ch3)2+ h2orclorconrnh2+r2nh+hlrr(h)orr3n+no reactionrclonch(ch3)2ch(ch3)2c2h5et3nnh2ohnhcoch3oh(rco)2ornh2+rsnhroo（碱碱）et3n+hclrscloorsoroo（碱碱）et3n+hcl+rohrnh2r2nhr3nphso2nhrphso2nr2naohnaoh不不溶溶不不溶溶phso2nr naphso2nhr溶溶解解不不溶溶h+phso2nr2不不溶溶h+phso2nr2不不

6、溶溶未未变变化化未未变变化化phso2cl +r3nh+r3nh溶溶解解phso2cl1o 胺胺2o 胺胺3o 胺胺不不溶溶（不不反反应应）nhnhonhonnch3h3cch3h2nso2h2nso2h2nso2nhcnh2nhh2nso2nh2h2nso2h2nso2nhrn2+cl-h2oohn2nano2nh2hcln2+cl-naclrnh2hno2rohh2on2nh ch3nano2+ hclnnoch3h2onhch3ch3nch3ch3noh2onano2+ hclnch3ch3ch3nch3ch3ch3nonano2+ hclnch3ch3nch3ch3nonano2+ h

7、clr3nh+no2-r3nhno2n2n2hno2例题例题12-2nh ch3nh2n(ch3)2n2nano2+ hclnh2brbrbrhbrnh2br2nh2+ i2nh2inh2nhcoch3ac2obr2nhcoch3brh3o+nh2brnh2(ch3co)2onhcoch3hno3hno3nhcoch3nhcoch3no2no2oh / h2ooh / h2onh2nh2no2no2在乙酸中在乙酸酐中（主要产物）（主要产物）nh2nh3hso4nh3hso4nh2h2so42naohno2no2hno3h2onh2nhso3hnh3hso4nh2h2so4h2o180so3hn

8、h3so2onh2nhcoch3ac2oclso3hnhcoch3so2clrnh2nhcoch3so2nhrh3o+nh2so2nhrh2nso2nh cnh2nhh2nso2nhnsh2nso2nhnn(ch3)2chcho +hnk2co3, 0oc75%(ch3)2cchnonh+h+nnnc6h5ch2xnch2c6h5 x-nch2c6h5x-nch2c6h5x-h2ooch2c6h5+nhn+ ch3c cloncch3oh2ooonoch2ch2cn1) ch2chcn2) h2o, ch3nh3+cl-(ch3)4n+cl-r3n + r xr3nr xch3nch2ch3c

9、h2ch2occh3oho人体神经刺激传导中的重要物质与神经分裂症的神经紊乱有关ch3(ch2)6cl + nacnh2orefluxc6h5ch2coch3 + ch3(ch2)3brnaoh, teba90%c6h5chcoch3ch2ch2ch2ch3+ ch2chch2clnaoh, teba80%ch2chch2ch2chch2teba = c6h5ch2n+(ch2ch3)3 cl-(ch3)4n+oh-r4ncl+ ag2oh2or4n oh+ agbrn2 偶氮化合物偶氮化合物rnnrnnnnnhch3ch2n2nn clnano2nh2hcln2+cl-naclarxarha

10、rcnaroharn2 xn2+hso4-ohn2+cu2(cn)2 , kcnh2so4 , h2on2+cl-cu2cl2 , hcln2+hso4-cnn2+cln2+nh2brnano2/h2so4h2on2so4hbrh2so4/h2o100ocohbrn2+so4h-h3po2h2o+ n2brbrbrch3brch3ch3ch3no2hno3h2so4ch3nh2fehclch3nhcoch3(ch3co)2och3nhcoch3brfebr2ch3brn2+hso4-nano2 , h2so405ch3nh2brh2ooh-ch3brh3po2 , h2on2+clsncl2

11、+ hclnhnh2hclohnhnh2苯肼盐酸盐苯 肼n2+cl-zn, hclnh2 + nh3 ohohch3nh2nnohn2+cl-oh+偶氮基偶氮基n2+cl-ohohnnnaoh , h2on nn(ch3)2ph56n=nn(ch3)2nn+:nn+:h2n+:ch3coonannhn+ ch3coohnnhnhc6h5nh3+clnnnh2h3ch3cbrohh3cbrohh3cbrn2 so4hh3cbrnh2h3cbrno2h3cno2h3ch3cbrohh3cbrnh2h3cbrno2h3cno2h3chno3h2so4br2fefehbrnano2h2so4h2o / hh3cbrn2 so4h h3ccoohh3ccnh3cn2 xh3cnh2h3cno2h3ch3ch3ccoohh3ccoohh3cmgx+co2h3cnh2h3cno2h3chno3h2so4fehclnano2,hclh2o / h+h3cn2clcucnh3ccnh3ccooh0-5oc brbrbrbr2febrbr2febrbrbrbr+brbrbrbrbrbrnh2nh2hno3h2so4fehclnano2 / hclbrbrbrbr2（过过量量）h2obrbrbrnh2nh20-5ocbrbrbrn2 clh3p