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1、Heart Failure Disease Management: Challenges, Solutions, 8(1): 30-41. Go AS, Mozaffarian D, Roger VL, et al. Circulation. 2013;127:e6-e245. Heart Failure Survival Circa 1980 Cumulative Survival (%) Years Heart Failure Survival 1990s Survival (%) Years Medtronic Heart Failure Strategy CRT New Heart F

2、ailure Opportunities CRT Strategy Extend Medtronic CRT Leadership Penetrate Global CRT Markets Develop Disruptive CRT Solutions Develop differentiated technology to provide elegant and effective solutions that benefit and delight all stakeholders Differentiate with revolutionary CRT solutions that m

3、ake implants dramatically faster, easier, and more predictable Leverage strategic market development initiatives to expand access for CRT indicated patients and accelerate market growth Demonstrate and Improve CRT Economic Value Deliver superior cost effectiveness by improving CRT response and reduc

4、ing complication rates 5.3 Fr, double cant shape With AdaptivCRT 5:815-820. Quadripolar LV Lead Design Short Bipolar Spacing For less phrenic nerve stimulation occurrence1 Next Gen CRT: MRI Safe MR Conditionally Safe (1.5T does not require any pocket. 2. LV Endocardial based concept Technology NG Mi

5、cra placed in the LV Subcutaneous device sends trigger for LV pacing Delivery Transseptal puncture to access LV Subcutaneous placed Reveal like or subQ ICD No transvenous leads 3. The epicardial pacer - Intro Technology VDD LV pacing and atrial sensing. Lead is connected to Micra, which is placed su

6、b-xiphoid w/o a pocket. Delivery Video-assisted placement through the pericardial space from a percutaneous sub-xiphoid stick. Helix could penetrate sub-epicardium. Devices Only Address Small HF Population Today HF 12 Million Patients potential exists for greater application in the future Patient Ma

7、nagement Co-morbidity Treatment Blood transfusion Insulin Pumps RDN* CPAP Dialysis Stents Heart Valves Surgical Tools Ablation Passive Therapy IABP ECP Active Therapy CRT LVADs Artificial Heart Diagnostics Echo Blood work Cardiocom CardioMEMs mHealth Heart Failure Devices *11 HF Readmissions 0153045

8、60 Time since Discharge (days) 0 10 20 30 40 50 % HF Readmission Risk Score 3 (n=19) 52% 5% Logrank p 4 (n=12) 54% 5% Logrank p 0.001 Risk Score 4 (n=44) * Results based on small sample sizes Unpublished data READMIT: Identifying Risk of HF Readmission Vision for Future Heart Failure Management Diag

9、nostic Device Data Multi-Patient Database Drug Compliance Confirmation Remote Delivery & Mobile Data Access Peripherals Data Device Data & Alerts Direct Patient Feedback, eLogs EMR Patient Information Aggregate Data: Analyze using Custom Logic & Algorithms PATIENTDATABASECARE CENTER Assess Data Per Guidelines Direct Patient Consultation Triage Critical Data For Physician Action PHYSICIAN Physician manages more patients in less time via concise set of critical

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