




版权说明:本文档由用户提供并上传,收益归属内容提供方,若内容存在侵权,请进行举报或认领
文档简介
1、Peptic Ulcer Disease 消化性溃疡病(PUD),Definition Epidemiology 3. Etiology and pathogenesis 4. Clinical presentations 5. Diagnosis 6. Complications 7. Treatment,Main Contents,1.Defenition of PUD,PUD is Ulceration 溃疡 of gastrointestinal mucosa 胃肠道黏膜 resulting from auto-digestion 自身消化 of gastric acid and pe
2、psin 胃蛋白酶.,Stomach 胃 (gastric ulcer, GU) Duodenum 十二指肠 (deodenal ucler, DU) Esophagus 食管 Gastro-jejunal anastomosis 胃-空肠吻合术 (post subtotal gastrectomy 胃大部切除术后) Terminal ileum diverticulum(回肠末段憩室) (Meckels diverticulum,heterotopic gastric mucosa 胃粘膜异位),Sites of peptic ulcer,Sites of peptic ulcer,Anas
3、tomotic ulcer,Sites of peptic ulcer,Sites of peptic ulcer,Difference of ulcer and erosion,Ulcer 溃疡 is a mucosal defect 黏膜损害 that penetrates 穿透 the muscularis mucosa(粘膜肌层) Erosion 糜烂 is a small, superficial mucosal break that no more than the muscularis mucosa(粘膜肌层),2.Epidemiology,Prevalence rate 患病率
4、 about 10% overall lifetime The incidence of DU was higher than GU The incidence of was male higher than female The predominant 主导的 age of DU is between 20 and 50 years old, whereas 然而 GU occurs in patients more than 40 years old The disease is more common in smokers,3. Etiology and pathogenesis,Gas
5、tric Mucosa vital signs are normal. Which of the following diagnostic studies should be done next? A) Abdominal ultrasonography B) Serologic testing for H. pylori C) Upper endoscopy D) Upper gastrointestinal barium study,Case 2: A 65-year-old woman was recently discharged from the hospital after tre
6、atment of upper gastrointestinal bleeding secondary to a duodenal ulcer. While hospitalized, she underwent 行 upper endoscopy, and antral biopsy specimens 胃窦活检标本 showed H. pylori. The patient was treated with appropriate antibiotics and a proton pump inhibitor. When seen for a follow-up visit 6 weeks
7、 after completing her medical regimen 治疗过程, she is asymptomatic 有症状的, and her hemoglobin is normal. Which of the following diagnostic studies should be done next? A) Repeat upper endoscopy with antral biopsies B) Hydrogen breath test C) 13C-urea breath test D) Serologic testing for H. pylori E) No a
8、dditional studies are indicated,Case 3: A 59-year-old man has a 3-month history of epigastric discomfort and nausea without weight loss, melena 黑便, or vomiting. Over-the-counter H2-receptor antagonists have been ineffective. The patient is otherwise healthy and takes no other medications. Physical e
9、xamination reveals mild epigastric tenderness to palpation. Upper endoscopy shows a 1-cm duodenal ulcer, and antral biopsy specimens demonstrate chronic gastritis and H. pylori infection. Which of the following is the most appropriate therapy for this patient? A) A proton pump inhibitor for 2 months B) An H2-receptor antagonist for 2 months C) A proton pump inhibitor and amoxicillin for 2 weeks D) A prot
温馨提示
- 1. 本站所有资源如无特殊说明,都需要本地电脑安装OFFICE2007和PDF阅读器。图纸软件为CAD,CAXA,PROE,UG,SolidWorks等.压缩文件请下载最新的WinRAR软件解压。
- 2. 本站的文档不包含任何第三方提供的附件图纸等,如果需要附件,请联系上传者。文件的所有权益归上传用户所有。
- 3. 本站RAR压缩包中若带图纸,网页内容里面会有图纸预览,若没有图纸预览就没有图纸。
- 4. 未经权益所有人同意不得将文件中的内容挪作商业或盈利用途。
- 5. 人人文库网仅提供信息存储空间,仅对用户上传内容的表现方式做保护处理,对用户上传分享的文档内容本身不做任何修改或编辑,并不能对任何下载内容负责。
- 6. 下载文件中如有侵权或不适当内容,请与我们联系,我们立即纠正。
- 7. 本站不保证下载资源的准确性、安全性和完整性, 同时也不承担用户因使用这些下载资源对自己和他人造成任何形式的伤害或损失。
最新文档
- 2024-2025年幼儿园保教体育活动计划
- 篮球校园文化建设计划
- 人教版八年级上册道德与法治教育创新计划
- 建筑装修安全文明施工管理体系与措施
- 财务承诺书范文及填写指南
- 服装店店长年度工作计划范文
- 油漆喷涂职业病危害防治措施
- 港口绿化带施工进度计划及工期保证措施
- 高一年级学生安全保障计划
- 初中道德与法治师资队伍建设计划
- CJ/T 340-2016绿化种植土壤
- 庐山市国有投资控股集团有限公司招聘笔试题库2025
- 2025年贵州省公务员录用考试《行测》真题及答案解析
- 第一单元:三视图的判断、确认与绘制专项练习-2023-2024学年五年级数学下册典型例题系列(原卷版)人教版
- 杨梅承包合同协议书
- 物理光学知到智慧树期末考试答案题库2025年山东理工大学
- 2024年新沪科版七年级上册数学教学课件 第1章 有理数 1.2 数轴、相反数和绝对值 第1课时 数轴
- 《高一物理力学进阶:动力学与能量学教学教案》
- 总监理工程师作业指导书
- GA/T 2160-2024法庭科学资金数据检验规程
- 2025年全国高压电工证(复审)理论考试试题(1000题)附答案
评论
0/150
提交评论