多元logistic回归实习题.doc

多元logistic回归1. 下面是子宫内膜癌的病例对照研究数据，暴露因素是雌激素。分 组使用过雌激素未使用过雌激素病例组55（a）128（b）对照组19（c）164（d）问题：使用过雌激素是否是子宫内膜癌的危险因素？危险强度为多少？2. 为了探讨糖尿病与血压、血脂等因素的关系，研究者对56例糖尿病病人和65例对照者进行病例-对照研究，收集了性别、年龄、学历、体重指数、家族史、吸烟、血压、总胆固醇、甘油三脂、高密度脂蛋白、低密度脂蛋白11个因素的资料，各因素的观察结果见下表。 问题：糖尿病的相关因素有哪些？如何解释相关因素的作用大小？如何评价模型优劣？因 素变量名赋 值性别X1男=1，女=2年龄X2学历X3小学以下=1，小学=2，初中=3，高中=4，大专及以上=5体重指数X424=1，2426=2， 26=3家族史X5无=1，有=2吸烟X6不吸=1 吸=2血压X7正常=1, 高=2总胆固醇X8甘油三脂X9高密度脂蛋白X10低密度脂蛋白X11糖尿病Y对照=0，病例=1编号性别年龄学历体重指数家族史吸烟血压总胆固醇甘油三脂高密度脂蛋白低密度脂蛋白糖尿病1160221114.301.501.242.3002148321114.601.321.152.3003263211124.601.151.152.3004168322114.151.431.073.2105145212113.421.220.632.3006145332114.160.960.982.6507159211114.321.021.053.4908168331113.801.422.860.8509263221113.871.552.440.81010258221115.420.874.463.14011144222124.351.015.132.20012146311213.421.261.400.28013262121123.181.381.670.48014265121113.300.851.920.69015258211124.411.052.971.79016122512225.101.633.240.96017169111215.091.503.290.75018255211123.981.410.664.25019266121114.271.352.301.05020147212114.191.242.491.65021247322114.191.042.431.02022264222114.471.603.010.95023263121114.231.504.041.14024164111214.161.441.631.95025170221214.771.081.792.69026148121113.781.001.192.63027264211115.201.561.211.28028147222124.251.063.340.94029254421123.561.351.240.88030257121114.801.263.190.93031145221114.650.922.990.79032162221124.231.153.281.07033152122123.700.852.552.97034250221114.111.232.541.67035250232213.851.352.341.09036158311113.011.081.861.14037154321213.021.231.550.40038160132114.161.022.460.80039260211125.121.313.501.11040263311114.301.402.800.97041165222113.670.722.290.66042137321115.461.453.560.94043252221124.351.133.861.11044246131113.600.872.271.00045263122123.160.682.301.23046263222123.821.361.981.18047260322114.631.282.460.33048158221124.050.852.600.77049265311123.801.421.850.79050143222114.981.485.071.03051158122215.041.133.770.77052261421113.530.741.660.55053146421123.501.531.940.44054158222114.830.832.820.96055254421112.881.041.580.55056245122113.311.691.630.72057238221124.131.383.921.26058222532213.660.730.710.53059144131224.151.311.900.73060149331124.211.592.491.02061249231123.971.344.101.10062241321113.130.751.620.57063144332114.461.332.860.27064148111214.061.542.350.80065148221114.331.604.811.17066251231112.751.100.841.59167260131124.501.220.743.27168167121212.701.000.960.80169148131213.540.631.211.90170258222213.090.822.052.50171241122215.120.711.382.61172152131214.811.660.753.29173254121114.931.430.613.12174160222224.381.561.933.71175167231123.611.141.172.60176243132224.231.341.263.06177161121124.971.321.050.45178252122124.421.311.242.30179160122224.801.650.852.92180150121224.441.491.202.91181245121224.831.661.040.96182245331215.681.431.441.44183260132115.852.571.393.03184234131224.692.041.122.86185254122214.303.100.752.05186258231224.671.762.290.84187261122224.912.562.370.86188153132223.440.742.770.78189146122123.951.651.182.04190272111223.861.321.192.30191158221223.680.971.311.97192250132225.174.312.541.63193260222124.072.452.421.19194255132223.381.152.680.49195234131224.752.452.510.32196264222223.891.291.930.61197262121215.731.724.410.66198165332213.680.971.970.61199143212223.571.172.821.081100252131225.501.793.951.401101261122213.826.472.671.111102253132223.081.392.281.121103164132123.871.191.720.351104138122119.472.382.260.861105260131113.061.032.070.671106244122224.170.942.210.831107162121216.792.653.820.681108260122223.030.892.140.901109255422224.511.242.980.871110160222214.981.973.310.991111265121115.012.593.281.021112163122114.281.693.010.601113167112124.020.932.760.741114142122215.121.584.051.361115160131213.581.512.121.431116157122225.481.773.761.021117169321114.811.732.950.861118162122215.721.243.500.961119155422224.711.202.920.881120167522215.411.302.991.081121165122214.101.101.720.7313. 研究人员对使用雌激素与子宫内膜癌发病间的关系进行了1 ：1配对的病例-对照研究。病例与对照按年龄相近、婚姻状况相同、生活的社区相同进行了配对。收集了年龄、雌激素药使用、胆囊病史、高血压和非雌激素药的使用的数据。变量定义及具体数据如下。对使用雌激素与子宫内膜癌发病间的关系作1ogistic回归分析。1:Match 配比组（匹配条件：年龄相近、婚姻状况相同、同一生活社区）2:Case(即y)y=1：病例， y=0：对照3:age _岁4:est est=0：未使用过雌激素， est=1：使用过雌激素5:gall gall=0：无胆囊病史， gall=1：有胆囊病史6hyperhyper=0: 不是高血压， hyper=1: 是高血压7:nonest nonest=0：未使用过非雌激素， nonest=1：使用过非雌激素matchcaseageestgallhypernonestmatchcaseageestgallhypernonest1162110131165110110620100310650000217910113218010012079000132079000031711101331681111307110113306800114172100034164100140711011340641001518310113516100015082000035061000161721011361631001607210113606310117170000137164100170700011370650000816510113817201018067000038072001091741001391681101907500003906911001016710114015710001006610014005710111117010014117410011107000004107410001216411014217401011206300014207400011316610114316711011306610014306810111416210004416210111406300004406210011517710014516910111507711114506901011618301114617310111608301004607210011716610114717710011706700114707610111818110014817110111807900004807110111917410014916410001907500004906410002016710015016400112006610115006510012116710015117901002106700115108210012217311115216310012207210015206400012317610115