Cefotaxime-d3-Cefotaxim-d-sub-3-sub-生命科学试剂-MCE-1932

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemECefotaxime-d3Cat.No.:HY-W654101Synonyms:Cefotaxim-d3;HR-756-d3分⼦式:C₁₆H₁₄D₃N₅O₇S₂分⼦量:458.48作⽤靶点:Isotope-LabeledCompounds;Antibiotic;Bacterial作⽤通路:Others;Anti-infection储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.溶解性数据体外实验DMSO:250mg/mL(545.28mM;Needultrasonicandwarming)MassSolvent1mg5mg10mgConcentration制备储备液1mM2.1811mL10.9056mL21.8112mL5mM0.4362mL2.1811mL4.3622mL10mM0.2181mL1.0906mL2.1811mLBIOLOGICALACTIVITY⽣物活性Cefotaxime-d3氘标记的Cefotaxime(HY-A0088A)。Cefotaxime耐β-内酰胺酶稳定的头孢素和第三代头孢素抗⽣素。Cefotaxime对多种⾰兰⽒阳性和⾰兰⽒性具有⼴谱抗⽣素活性。REFERENCES[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-216.[2].WoodfieldJC,etal.Acomparisonoftheprophylacticefficacyofceftriaxoneandcefotaximeinabdominalsurgery.AmJSurg.2003Jan;185(1):45-9.[3].ScholzH,etal.Prospectivecomparisonofceftriaxoneandcefotaximefortheshort-termtreatmentofbacterialmeningitisinchildren.1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemEChemotherapy.1998Mar-Apr;44(2):142-7.[4].ELFrancke,etal.Useofcefotaxime,abeta-lactamasestablecephalosporin,inthetherapyofseriousinfections,includingthoseduetomultiresistantorganisms.AmJMed.1981Sep;71(3):435-42.[5].GumsJG,etal.Differencesbetweenceftriaxoneandcefotaxime:microbiologicalinconsistencies.AnnPharmacother.2008Jan;42(1):71-9.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-5895