Allylthiourea-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEAllylthiourea(Standard)Cat.No.:HY-B0543RCASNo.:109-57-9分⼦式:C₄H₈N₂S分⼦量:116.18作⽤靶点:ReactiveOxygenSpecies作⽤通路:Immunology/Inflammation;MetabolicEnzyme/Protease;NF-κB储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性Allylthiourea(Standard)Allylthiourea的分析标准品。本产品⽤于研究及分析应⽤。Allylthiourea能选择性抑制氨的氧化。Allylthiourea通常⽤于抑制硝化，通过靶向氨单加氧酶作⽤并螯合活性位点中的铜来抑制其活性。Allylthiourea还具有抗癌活性，对MCF-7细胞系具有细胞毒性，IC50为5.22mM。Allylthiourea可⽤于微污染物⽣物降解性与癌症领域研究[1][2][3][4]。REFERENCES[1].Ginestet,P.,etal.,Estimationofnitrifyingbacterialactivitiesbymeasuringoxygenuptakeinthepresenceofthemetabolicinhibitorsallylthioureaandazide.ApplEnvironMicrobiol,1998.64(6):p.2266-8.[2].Yu,Y.,J.A.Ramsay,andB.A.Ramsay,Useofallylthioureatoproducesolublemethanemonooxygenaseinthepresenceofcopper.ApplMicrobiolBiotechnol,2009.82(2):p.333-9.[3].TatariK,etal.Challengesinusingallylthioureaandchlorateasspecificnitrificationinhibitors[J].Chemosphere,2017,182:301-305.[4].WidiandaniT,etal.NewN-allylthioureaderivatives:synthesis,moleculardockingandinvitrocytotoxicitystudies[J].TropicalJournalofPharmaceuticalResearch,2018,17(8):1607-1613.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:0