胸外科英文文献汇报2017.11.23

AnatomicalSegmentectomyandWedgeResections

AreAssociatedwithComparableOutcomesforPatientswithSmallcT1N0Non–SmallCellLungCancer

肺段与肺楔形切除cT1N0NSCLC对比分析2017.11.23

Objectives

Sublobarresection(亚肺叶切除)isadvocatedforpatientswithNSCLCandcompromisedcardiopulmonaryreserve(心肺功能储备差),andforselectedpatientswithearlystagedisease(选择性早期肺癌患者).Anatomicsegmentectomy(AS)hastraditionallybeenconsideredsuperior(优于)towedgeresection(WR),butwell-balancedcomparativestudiesarelacking.Wehypothesize（猜测）thatWRandASareassociatedwithcomparableoncologicoutcomesforpatientswithcT1N0NSCLC.

NewYorkPresbyterianHospital(美国纽约长老会医院)StilesThoracOncolMethods

Aretrospectivereview（回顾性分析）ofaprospectivedatabase（前瞻性数据库）wasperformed(2000–2014)forcT1N0patients,excludingpatientswithmultipleprimarytumors,carcinoidtumors,adenocarcinomainsitu,andminimallyinvasiveadenocarcinoma.（多原发肿瘤，类癌，原位腺癌，低侵袭性腺癌）Demographic（人口统计）,clinical,andpathologicaldatawerereviewed.Overallsurvival(OS)anddisease-freesurvival(DFS)wereestimatedusingtheKaplan-Meiermethodanddifferencescomparedusinglog-ranktest（对数秩检验）.Multivariableanalysis(MVA)（多变量分析）offactorsaffectingDFSwasperformedbyCoxregressionanalysis（考克斯回归分析）.Methods

Forfurthercomparisonoftheeffectofresectiontypeonsurvival,propensityscorematching(i.e,byage,sex,Charlsoncomorbidityindex（察尔森指数),percentforcedexpiratoryvolumein1second(FEV1%),clinicaltumorsize,andtumormaximumstandardizeduptakevalue(肿瘤最大标准化摄取值SUVmax),wa