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组织胚胎学课件
中国医科大学基础医学院组胚—英文教学组1业精于勤荒于嬉行成于思毁于随→【医学生物PPT,欢迎收藏分享】豆丁网友组织胚胎学课件
中国医科大学1业精于勤荒于嬉行成于思毁HUMANEMBRYOLOGYDepartmentofHistologyandEmbryologyChinaMedicalUniversityHUMANChapter4
FurtherDevelopmentofEmbryo
Chapter4FormationanddifferentiationoftrilaminargermdiscFormationanddifferentiation1.formationofepiblastandhypoblast
:
Bythe8thday,theinnercellmassdifferentiatesintotwolayersofcells
epiblast(columnar)hypoblast(cuboidal)bilaminargermdisc1.formationofepiblastandAmnioniccavityepiblasthypoblastBilaminargermdiscAmnionicepiblasthypoblastBila---epiblast:primaryectodermamnioticcavity:amnioticfluidroof:amniogeniccellsfloor:epiblast---epiblast:primaryectoderm---hypoblast:primaryendodermhypoblast→Heuser’smembrane→primaryyolksac---hypoblast:primaryendoderAmnioniccavityepiblasthypoblastBilaminargermdiscExtra-embryonicmesodermPrimaryyolksacAmnioniccavityepiblasthypoblBodystalkExtra-embryoniccavityExtra-embryonicmesodermPrimaryyolksacsecondaryyolksacBodystalkExtra-embryonicExtra
extra-embryonicmesoderm→extra-embryoniccavity(chorioniccavity)--viscerallayer--parietallayer/secondaryyolksac:yolksac---bodystalk(connectingstalk):formedbyextra-embryonicmesodermextra-embryonicmesoderm→2.formationofmesoderm:intheearlyofthe3rdweek---primitivestreak:cellsofepiblastproliferatetoformalongitudinalarrangedcellcord*determinationofheadandtailofgermdisc2.formationofmesoderm:2.formationofmesoderm:intheearlyofthe3rdweek---primitivestreak---primitivenode(primitiveknot)2.formationofmesoderm:int2.formationofmesoderm:intheearlyofthe3rdweek---primitivestreak:---primitivenode(primitiveknot)---primitivepit(blastopore)2.formationofmesoderm:int【医学生物】组织胚胎学课件4---mesoderm:intra-embryonicmesoderm---endoderm:hypoblastcellsarereplacedbyepiblastcells---ectoderm:epiblastchangedthenameintoectoderm---mesoderm:intra-embryonicm
bytheendofthe3rdweek
trilaminargermdisc:endoderm+mesoderm+ectoderm
bytheendofthe3rdweek---headprocess→notochordaltube→notochord---buccopharyngealmembrane---cloacalmembranenotochord---headprocess→notochordaltu3.differentiationoftrilaminargermdisc4th–8thweeks---differentiation:samecellswhichareprimordialandinmuturedifferentiateintodifferentcellswhichhavespecificstructureandfunction---induction:sometissueseffectthedifferentiation,anddeterminethedifferentiatingorientationofanothertissue3.differentiationoftrilamina(1)
differentiationofectoderm:from18th–19thdays---neuralplate:neuro-epithelium(neuralectoderm):pseudostratifiedcolumnarepi.neuralplateNotochord(1)
differentiationofectoder(1)
differentiationofectoderm:from18th–19thdays---neuralplate---neuralgroove---neuralfoldNeuralgrooveNotochord(1)
differentiationofectoderNeuraltubeAnteriorandposteriorneuropores---neuraltube:→CNS/anteriorneuropore:closedby25thdays/posteriorneuropore:closedby27thdaysNeuraltubeAnteriorandposteranencephalySpinabifidaanencephalySpinabifida---neuraltube:CNS---neuralcrest:twolinesofcellcords→ganglions---neuraltube:CNS(2)differentiationofmesoderm:17thdayNeuralgrooveIntermediatemesodermLateralmesoderm
paraxialMesodermendoderm(2)differentiationofmesoderm---paraxialmesodermsomite:20thdays,3pairs/perday,42-44pairsbytheendof5thweeks-sclerotome:→bone,cartilage-dermatome:→dermisandhypodermis-myotome:→skeletalmuscle---paraxialmesodermIntermediatemesodermNeuralcanalSomiteendodermIntraembryoniccavityIntermediateNeuralcanalSomite---intermediatemesoderm:→kidneyandreproductivesystem---intermediatemesoderm:---lateralmesoderm:Intra-embryoniccoelom:→bodycavityparietalorsomaticmesoderm:→muscle,CT,parietallayerofpleura,peritoneumandpericardiumvisceralorsplanchnicmesoderm:→muscle,CTofdigestivetract,viscerallayerofpleura,peritoneumandpericardium---lateralmesoderm:ParietalmesodermvisceralmesodermIntra-embryoniccavityParietalvisceralIntra-embryon3.differentiationofendoderm:
primitivegut:→digestive,respiratoryandurinarysystem
foregutmidguthindgutCloacalmembraneoropharyngealmembrane3.differentiationofendoderm【医学生物】组织胚胎学课件41.Embryonicperiodis
A.fromfertilizationtotheendofweek2
B.fromfertilizationtotheendofweek8
C.fromweek3totheendofweek8D.fromweek5totheendofweek8E.fromweek9untilbirth2.Howlongwillanindividualstayintheuterusofitsmother?
A.18weeks
B.28weeks
C.38weeks
D.48weeks
E.58weeksBC1.EmbryonicperiodisBC3.Whatispenetratedbyaspermatozoonduringtheprocessoffertilization
A.oogonium
B.primaryoocyte
C.secondaryoocyteD.primaryfollicleE.primordialfollicle4.Whichproteinisreceptorofspermatozoaonthezonapellucida?
A.ZP1
B.ZP2
C.ZP3
D.ZP4
E.ZP5C
C3.Whatispenetratedbyaspe5.Thetimeofimplantationis
A.from1st-2nddayto7th-8thday
B.from3rd-4thdayto9th-10thday
C.from5th-6thdayto11th-12thdayD.from7th-8thdayto13th-14thdayE.from9th-10thdayto15th-16thday6.Whichstructureisnotbelongtoearlyblastocyst?
A.trophoblast
B.zonapellucida
C.innercellmass
D.blastocoele
E.endodermC
E
5.Thetimeofimplantationis7.Whichisnotcorrectaboutimplantation
A.blastocystwillbeimbeddedintheendomytrium
B.zonapellucidadisappears
C.polartrophoblastsecretesproteinaseD.endomytriumisinproliferative
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