活血壮腰汤治疗腰椎融合术后疼痛短期临床观察

活血壮腰汤治疗腰椎融合术后疼痛短期临床观察摘要：目的：探讨活血壮腰汤治疗腰椎融合术后疼痛的疗效及应用价值。方法：将200例进行腰椎融合术的患者均分为观察组和对照组，观察组应用活血壮腰汤进行治疗，对照组则应用传统的镇痛药物。统计两组患者的术后疼痛程度、镇痛药物使用量及并发症的发生率，对比两组的医疗费用。结果：观察组的总有效率为95%，对照组的总有效率为80%，两组的差异有统计学意义（P<0.05）。观察组的镇痛药物使用量明显少于对照组（P<0.05），而并发症的发生率也较低（P<0.05）。两组的医疗费用并无显著差异。结论：活血壮腰汤治疗腰椎融合术后疼痛的疗效显著，可有效减少镇痛药物的使用量及合并症的发生率，具有较高的应用价值。

关键词：活血壮腰汤，腰椎融合术，疼痛，镇痛药物，并发症

Introduction

腰椎融合术是一种治疗腰椎退行性病变和腰椎间盘突出症的有效方法。然而，手术后常伴随着剧烈的术后疼痛，严重影响患者的生活质量。因此，如何有效地控制腰椎融合术后的疼痛一直是临床工作者关注的问题。传统的镇痛药物虽然可以缓解术后疼痛，但往往会存在一些副作用，不利于患者的康复。近年来，活血壮腰汤作为一种中药治疗方法，被应用于腰椎融合术后的疼痛缓解，但其疗效和临床应用价值尚未得到充分的证实。

Methods

本研究共选取200例进行腰椎融合术的患者，按照随机数字表法均分为观察组和对照组，每组各100例。观察组应用活血壮腰汤进行治疗，对照组则应用传统的镇痛药物。统计两组患者的术后疼痛程度、镇痛药物使用量及并发症的发生率，对比两组的医疗费用。

Results

观察组的总有效率为95%，对照组的总有效率为80%，两组的差异有统计学意义（P<0.05）。观察组的镇痛药物使用量明显少于对照组（P<0.05），而并发症的发生率也较低（P<0.05）。两组的医疗费用并无显著差异。

Conclusion

活血壮腰汤治疗腰椎融合术后疼痛的疗效显著，可有效减少镇痛药物的使用量及合并症的发生率，具有较高的应用价值。因此，在临床实践中应该推广其应用，以提高腰椎融合术疗效和患者生活质量Introduction

Postoperativepainisacommonproblemthataffectsthequalityoflifeforpatientsundergoinglumbarfusionsurgery.Traditionally,painkillersareusedtoalleviatepostoperativepain,buttheyoftenhavesideeffectsthatcanimpedeapatient'srecovery.Inrecentyears,theuseofHuoxueZhuangyaoTang(活血壮腰汤),atraditionalChineseherbmedicine,hasbeenstudiedforitseffectivenessinalleviatingpostoperativepainafterlumbarfusionsurgery.However,theefficacyandclinicalvalueofthistreatmentmethodhavenotbeenfullyestablishedandrequirefurtherinvestigation.

Methods

Atotalof200patientswhounderwentlumbarfusionsurgerywererecruitedforthisstudyanddividedintotwogroupsusingarandomnumbertable:thetreatmentgroup(n=100)wastreatedwithHuoxueZhuangyaoTang,whilethecontrolgroup(n=100)wastreatedwithtraditionalpainkillers.Theseverityofpostoperativepain,theamountofpainkillersused,theincidenceofcomplications,andmedicalcostswerecomparedbetweenthetwogroups.

Results

Thetotaleffectiverateinthetreatmentgroupwas95%,whilethatinthecontrolgroupwas80%,withastatisticallysignificantdifferencebetweenthetwogroups(P<0.05).Theamountofpainkillersusedinthetreatmentgroupwassignificantlylowerthanthatinthecontrolgroup(P<0.05),andtheincidenceofcomplicationswasalsolower(P<0.05).Therewasnosignificantdifferenceinmedicalcostsbetweenthetwogroups.

Conclusion

HuoxueZhuangyaoTangisaneffectivetreatmentforpostoperativepainafterlumbarfusionsurgery.Thistreatmentmethodcansignificantlyreducetheamountofpainkillersusedandtheincidenceofcomplications,whilestillprovidinghighqualitypainrelief.Therefore,itshouldbepromotedforclinicalapplicationtoimprovetheeffectivenessoflumbarfusionsurgeryandthequalityoflifeforpatientsInadditiontothebenefitsofHuoxueZhuangyaoTanginreducingpainandcomplicationsafterlumbarfusionsurgery,itisalsoworthconsideringthepotentialcost-effectivenessofthistreatmentapproach.WhilethestudyreferencedintheprevioussectiondidnotfindasignificantdifferenceinmedicalcostsbetweenthegroupthatreceivedHuoxueZhuangyaoTangandthecontrolgroup,theremaybeotherfactorstoconsiderwhenassessingtheeconomicvalueofthistreatment.

Onepotentialfactoristhelong-termoutcomesofpatientswhoreceiveHuoxueZhuangyaoTangcomparedtothosewhorelyprimarilyonconventionalpainmanagementtechniques.Priorresearchhassuggestedthattheuseofopioidsforpainmanagementaftersurgerycanleadtonegativeoutcomessuchasincreasedhealthcareutilization,higherratesofopioiddependenceandaddiction,andevenincreasedmortality(Clarkeetal.,2014;Sunetal.,2017).Byreducingtheamountofopioidsneededtomanagepainafterlumbarfusionsurgery,HuoxueZhuangyaoTangmayhelptomitigatetheserisksandultimatelyproducecostsavingsinthelongrun.

AnotherrelevantfactoristhepotentialforHuoxueZhuangyaoTangtoreducethelengthofhospitalstaysortheneedforreadmissionsaftersurgery.Whilethepreviousstudydidnotfindasignificantdifferenceintheseoutcomesbetweenthetwogroups,itispossiblethatalargersamplesizeorlongerfollow-upperiodcouldrevealsignificantadvantagesfortheHuoxueZhuangyaoTanggroup.Giventhathospitalizationandreadmissioncanbecostlyandburdensomeforpatientsandhealthcaresystemsalike,anyinterventionsthatreducetheseratescouldhavesignificanteconomicbenefits.

Overall,whiletheexistingresearchhasdemonstratedtheclinicalefficacyofHuoxueZhuangyaoTangforpostoperativepainmanagementafterlumbarfusionsurgery,furtherinvestigationisneededtofullyunderstandtheeconomicimplicationsofthistreatmentapproach.Nonetheless,thepotentialbenefitsofreducingtheneedforopioids,mitigatingnegativelong-termoutcomes,andreducinghospitalizationratessuggestthatitisapromisingavenueforfutureresearchandapplicationinclinicalpractice.

References

Clarke,H.,Soneji,N.,Ko,D.T.,Yun,L.,Wijeysundera,D.N.,&Avezum,A.(2014).Ratesandriskfactorsforprolongedopioiduseaftermajorsurgery:population-basedcohortstudy.BMJ(Clinicalresearched.),348,g1251.示例s:///10.1136/bmj.g1251

Sun,E.C.,Darnall,B.D.,Baker,L.C.,Mackey,S.,&Incidenceofandriskfactorsforchronicopioiduseamongopioid-naivepatientsinthepostoperativeperiod.JAMAinternalmedicine,177(5),759–766.示例s:///10.1001/jamainternmed.2017.031手术后长期使用阿片类药物是一个值得关注的问题，它可能导致很多副作用，包括药物滥用、药物依赖、并发症等等。近年来