S-Gboxin-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemES-GboxinCat. No.: HY-111652分式: CHFINO分量: 600.45作靶点: Others作通路: Others储存式: Powder -20C 3 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 93.33 mg/mL (155.43 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制

2、备储备液1 mM 1.6654 mL 8.3271 mL 16.6542 mL5 mM 0.3331 mL 1.6654 mL 3.3308 mL10 mM 0.1665 mL 0.8327 mL 1.6654 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DM

3、SO 40% PEG300 5% Tween-80 45% salineSolubility: 9.33 mg/mL (15.54 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 9.33 mg/mL (15.54 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 9.33 mg/mL (15.54 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of

4、Small Molecules 您边的抑制剂师www.MedChemE物活性 S-GboxinGboxin 的功能类似物，S-Gboxin 抑制和胶质母细胞瘤的长，IC50 为 470 nM 1。具有抗肿瘤活性 1。REFERENCES1. Shi Y, et al. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. 2019 Mar;567(7748):341-346.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 021