Iloprost-Ciloprost-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEIloprostCat. No.: HY-A0096CAS No.: 78919-13-8Synonyms: Ciloprost; ZK 36374分式: CHO分量: 360.49作靶点: Prostaglandin Receptor作通路: GPCR/G Protein储存式: Pure form -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 1

2、00 mg/mL (277.40 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.7740 mL 13.8700 mL 27.7400 mL5 mM 0.5548 mL 2.7740 mL 5.5480 mL10 mM 0.2774 mL 1.3870 mL 2.7740 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加

3、助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (6.94 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (6.94 mM); Clear solution1/2 Master of Small

4、 Molecules 您边的抑制剂师www.MedChemE3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (6.94 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Iloprost (ZK 36374)种前列环素PGI2的合成类似物。REFERENCES1. Della Bella S, et al. Novel mode of action of iloprost: in vitro down-regulation of endothelial cell adhesion molecul

5、es. ProstaglandinsOther Lipid Mediat. 2001 Jun;65(2-3):73-83.2. van der Giessen WJ, et al. The effect of the stable prostacyclin analogue ZK 36374 on experimental coronary thrombosis in the pig.Thromb Res. 1984 Oct 1;36(1):45-51.3. Addonizio VP Jr, et al. Prevention of heparin-induced thrombocytopenia during open heart surgery with iloprost (ZK36374). Surgery.1987 Nov;102(5):796-807.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;