Doripenem-monohydrate-S-4661-monohydrate-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEDoripenem (monohydrate)Cat. No.: HY-B0187ACAS No.: 364622-82-2Synonyms: S 4661 monohydrate分式: CHNOS分量: 438.52作靶点: Bacterial作通路: Anti-infection储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO :

2、 50 mg/mL (114.02 mM; Need ultrasonic)H2O : 10 mg/mL (22.80 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.2804 mL 11.4020 mL 22.8040 mL5 mM 0.4561 mL 2.2804 mL 4.5608 mL10 mM 0.2280 mL 1.1402 mL 2.2804 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案

3、，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 3 mg/mL (6.84 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 3 mg/mL (6.84 mM); Clear solution1/2

4、 Master of Small Molecules 您边的抑制剂师www.MedChemE3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 3 mg/mL (6.84 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Doripenem合物谱的-内酰胺抗素，抗 谱覆盖兰阳性，阴性和厌氧菌。户使本产品发表的科研献 Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00282-18. Biomed Res Int. 2018 Jul 2;2018:3579832

5、.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Anderson DL. Doripenem. Drugs Today (Barc). 2006 Jun;42(6):399-404.2. Jones RN, et al. Doripenem (S-4661), a novel carbapenem: comparative activity against contemporary pathogens including bactericidalaction and preliminary in vitro methods evaluations. J Antimicrob Chemother. 2004 Jul;54(1):144-54. Epub 2004 Jun 9.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792