Arecoline-hydrobromide-Arecoline-bromide-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEArecoline hydrobromideCat. No.: HY-B0489CAS No.: 300-08-3Synonyms: Arecoline bromide分式: CHBrNO分量: 236.11作靶点: mAChR作通路: GPCR/G Protein; Neuronal Signaling储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据

2、体外实验 H2O : 50 mg/mL (211.77 mM; Need ultrasonic)DMSO : 50 mg/mL (211.77 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 4.2353 mL 21.1766 mL 42.3531 mL5 mM 0.8471 mL 4.2353 mL 8.4706 mL10 mM 0.4235 mL 2.1177 mL 4.2353 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储

3、备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (10.59 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)1/2 Master

4、 of Small Molecules 您边的抑制剂师www.MedChemESolubility: 2.5 mg/mL (10.59 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 25 mg/mL (105.88 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Arecoline 氢溴酸盐 (Arecoline bromide)毒蕈碱酰胆碱受体（mAChR）激动剂。REFERENCES1. Ghelardini, C., et al., M1 receptor activ

5、ation is a requirement for arecoline analgesia. Farmaco, 2001. 56(5-7): p. 383-5.2. Yang, Y.R., et al., Arecoline excites rat locus coeruleus neurons by activating the M2-muscarinic receptor. Chin J Physiol, 2000. 43(1):p. 23-8.3. Xie, D.P., et al., Arecoline excites the colonic smooth muscle motility via M3 receptor in rabbits. Chin J Physiol, 2004. 47(2): p. 89-94.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;