Mcl1-IN-2 _Bcl-2 Family 抑制剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEMcl1-IN-2Cat. No.: HY-12826CAS No.: 292057-76-2分式: CHNOS分量: 333.41作靶点: Bcl-2 Family作通路: Apoptosis储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 33.33 mg/mL (99.97 mM; Need ultrasonic)Mass

2、Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.9993 mL 14.9966 mL 29.9931 mL5 mM 0.5999 mL 2.9993 mL 5.9986 mL10 mM 0.2999 mL 1.4997 mL 2.9993 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分

3、指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (7.50 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (7.50 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE物活性 Mcl1-IN-2种髓细胞因 1 (Mcl-1)

4、抑制剂。IC50 & Target Mcl-1体外研究 Mcl1-IN-2 (Compound 2) is a Mcl-1 inhibitor, though without a reported IC50 value 1.REFERENCES1. Richard DJ, et al. Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker. BioorgMed Chem. 2013 Nov 1;21(21):6642-9.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: