Hexachlorophene-Hexachlorofen-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEHexachloropheneCat. No.: HY-12637CAS No.: 70-30-4Synonyms: Hexachlorofen分式: CHClO分量: 406.9作靶点: Bacterial; Potassium Channel作通路: Anti-infection; Membrane Transporter/Ion Channel储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6

2、months-20C 1 month溶解性数据体外实验 DMSO : 100 mg/mL (245.76 mM)H2O : 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (6.14 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)1/2 Master of Small Molecules 您边的抑制剂师www.MedChemESolubility: 2.5 mg/mL (6.14 mM); Clear solution3. 请依序添加每种溶剂：

3、 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (6.14 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Hexachlorophene (Hexachlorofen)种有效的抗 (antibacterial) 剂，在浓度下，能够导致原质体的裂解和细 内细胞内容物的渗漏 1。Hexachlorophene (Hexachlorofen) 为 KCNQ1/KCNE1 (种电压门控钾离通道 voltage-gated potassium channel) 激活剂，EC50 值为 4.61 M。可于严重 律失常症的研究2。

4、IC50 & Target EC50: 4.61 M (KCNQ1/KCNE1) 2户使本产品发表的科研献 Viruses. 2019 Apr 25;11(4). pii: E385.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Lloyd WJ, et al. Cyclohexane triones, novel membrane-active antibacterial agents. Antimicrob Agents Chemother. 1988 Jun;32(6):814-8.2. Zheng Y, et al. Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator which rescues LQTs mutants. PLoS One.2012;7(12):e51820.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>