Bimatoprost-AGN-192024-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBimatoprostCat. No.: HY-B0191CAS No.: 155206-00-1Synonyms: AGN 192024分式: CHNO分量: 415.57作靶点: Prostaglandin Receptor作通路: GPCR/G Protein储存式: Powder -20C 3 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 100 mg/mL (240.63

2、mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.4063 mL 12.0317 mL 24.0633 mL5 mM 0.4813 mL 2.4063 mL 4.8127 mL10 mM 0.2406 mL 1.2032 mL 2.4063 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体

3、内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.75 mg/mL (6.62 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.75 mg/mL (6.62 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oi

4、l1/2 Master of Small Molecules 您边的抑制剂师www.MedChemESolubility: 2.75 mg/mL (6.62 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Bimatoprost前列腺素类似物，可作于眼内压和青光眼。REFERENCES1. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011Jan;55(1):22-7.2. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-589559