噬血细胞综合征课件.

1、 Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics流行病学流行病学 Capital Institute of Pediatrics Capital Institute of Pediatrics家族性噬血细胞综合征家族性噬血细胞综合征 Capital Institu

2、te of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics继发性继发性HLHHLH 肿肿 瘤瘤感感 染染其其 他他风湿免疫病风湿免疫病药药 物物免疫缺陷病免疫缺陷病 Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics发病机制发病机

3、制T细胞、细胞、NK细胞异常活化、凋亡缺陷细胞异常活化、凋亡缺陷活化活化T细胞、细胞、NK细胞细胞 感感 染染Th1/Th2IFN-、IL-6、GM-CSF细胞因子风暴细胞因子风暴肿瘤细胞肿瘤细胞活化巨噬细胞吞噬血细胞活化巨噬细胞吞噬血细胞活化活化T细胞、巨噬细胞浸润组织细胞、巨噬细胞浸润组织细胞因子作用于组织细胞因子作用于组织组织损伤组织损伤 Capital Institute of Pediatrics Capital Institute of Pediatrics高细胞因子风暴模式高细胞因子风暴模式 Capital Institute of Pediatrics Capital Inst

4、itute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Ped

5、iatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capi

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7、e of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of PediatricsIFN-、IL-6、GM-CSFT细胞、细胞、NK细胞异常活化、凋亡缺陷细胞异常活化、凋亡缺陷活化活化T细胞、细胞、NK细胞细胞 感感 染染Th1/Th2细胞因子风暴细胞因子风暴肿瘤细胞肿瘤细胞活化巨噬细胞吞噬血细胞活化巨噬细胞吞噬血细胞活化活化T细胞、巨噬细胞浸润组织细胞、巨噬细胞浸润组织细胞因子作用于组织细胞

8、因子作用于组织组织损伤组织损伤 Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatr

9、ics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics治疗新进展治疗新进展 Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatric

10、s Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics Capital In

11、stitute of Pediatrics Capital Institute of Pediatrics Capital Institute of Pediatrics诊断：1、病脑 2、瑞氏综合症 3、胆囊炎？4、 Capital Institute of Pediatrics Capital Institute of Pediatrics诊断：骨髓急性增生停滞 Capital Institute of Pediatrics Capital Institute of Pediatrics诊断：EB病毒相关性噬血细胞增多症。 Capital Institute of Pediatrics Capital Institute of Pediatrics Capital Institu