牡丹江农垦地区心血管危险因素流行病学调查

1、牡丹江农垦地区心血管危险因素流行病学调查    【关键词】  ,心血管危险因素；流行病学；发病率；高血压；高血糖；胆固醇；低密度脂蛋白   摘要  目的  了解牡丹江农垦地区心血管危险因素的患病率和分布特征。方法  在牡丹江垦区随机抽取8个局直单位，4个农场，在12个人群随机抽取各年龄组有代表性的样本，统计不同年龄、不同性别人群的心血管危险因素高血压(EH)、高血糖、血脂异常的患病情况。 结果  共抽样调查2574岁居民1348人，EH患病率24.5%,其中男性为28.5%,女性为21

2、.4%,男性EH患病率明显高于女性(P= 0.002),EH患病率与年龄正相关，r=0.98，(P<0.05)。高血糖的患病率为9.7%,其中男性为 11.1%,女性为8.4%，男性高血糖患病率高于女性(P= 0.031),高血糖患病率随年龄增加而增高，但不呈直线相关,r=0.87(P>0.05)。高胆固醇血症患病率43.7%,其中男性为47.5%,女性为40.3%,男性高胆固醇血症患病率高于女性(P=0.008),2564岁高胆固醇血症患病率与年龄正相关，r=1(P<0.01 )。低密度脂蛋白胆固醇(LDL-C)增高患病率13.6%,其中男性为14.7%,女性为12.7%,

3、男女LDL-C增高患病率无明显差异(P=0.273),发病率与年龄不相关，r=0.26(P>0.05)。 结论  牡丹江垦区心血管危险因素高发病率正成为危害本地区人民健康的杀手,应引起心血管领域的充分重视,以加强心血管疾病的1级、2级预防。    关键词  心血管危险因素；流行病学；发病率；高血压；高血糖；胆固醇；低密度脂蛋白       Investigation of the prevalence and distributing feature of cardiovascu

4、lar disease risk factors in  Mudanjiang land reclamation  area    Abstract  Objective  To investigate the  prevalence and distributing feature of cardiovascular desease risk factors in Mudanjiang land reclamation area.Methods  Selected random samples aged

5、 2574 years were used to investigate and analyze the prevalence and distributing feature of cardiovascular desease risk factors (EH,hyperglycemia,hyperlipidemia) in different age,sex groups.The samples were collected from 8 units and 4 farms in Mudanjiang land reclamation area.Results  A total

6、of 1348 adults were surveyed.The  prevalence rate of EH was 24.5%,28.5% and 21.4% for the general population,the male and female,respectively.The female had EH more frequently than the males(P=0.002).Linear correlation analysis showed that the prevalence rate of EH was correlated positively wit

7、h age,r=0.98(P<0.05).The  prevalence rate of hyperglycemia was 9.7%,the males and females were 11.1% and 8.4% for the general population respectively.The females had hyperglycemia more frequently than the males(P=0.031).The prevalence rate of hyperglycemia increased with aging,but linear cor

8、relation analysis showed that the prevalence rate of hyperglycemia was not correlated positively with age,r=0.87(P>0.05).The  prevalence rate of hypercholesterolemia was 43.7%,the males and females were 11.1% and 8.4% respectively.The females had hypercholesterolemia more frequently than the

9、 males(P=0.008).In 2564 years,the prevalence rate of hypercholesterolemia was correlated positively with age,r=1(P<0.01).The  prevalence rate of LDL-C increasing was 13.6%,the males and female were 14.7% and 12.74% respectively.The female was similar to the male(P=0.273).The prevalence rate

10、of LDL-C increasing was not correlated with age,r=0.26(P>0.05).  Conclusion  Hypertension(EH),hyperglycemia，hyperlipidemia is becomeing an important component of the publice health problem of cardiovascular diseases in the area of land reclamation and cultivation of Mudanjiang. 

11、60;  Key words  cardiovascular risk factor;epidemiology;morbidity;hypertension;hyperglycemia;cholesterol;LPL    在我国，心脑血管病已是严重威胁人民健康造成死亡的第一致死原因。各种公认的危险因素,诸如高血压、高血糖、高胆固醇血症、低密度脂蛋白胆固醇水平增高等，是造成心脑血管疾病的基础。本研究旨在调查牡丹江农垦地区心血管危险因素的发病情况，以便为本地区心脑血管疾病的1级、2级预防提供科学依据。    1

12、60; 资料与方法    1.1  研究人群  以牡丹江农垦地区20万人口作为监测人群，在2001年，从牡丹江垦区局直单位和各农场中随机抽取8个局直单位和4个农场，再在各个人群中按名册随机抽取一定数目的个体作为研究对象，进行危险因素检测。共抽样调查1500人。    1.2  研究内容和方法  调查研究开始前，制订调查表格，对参与调查工作的主要医务人员进行培训，内容包括人群抽样及调查方法，各种观察指标项目及诊断标准，血压测量方法，调查表的填写等。    高血压人群是

13、取右臂偶测血压3次均值140/90 mmHg及有高血压病史正在服降压药(无论即时测血压正常与否)的个体，血脂、血糖由牡丹江农管局中心医院检验科采用中华医学会推荐的酶法测定，并负责质量监控,空腹血糖6.1 mmol/L为高血糖，空腹血糖6.17.0 mmol/L为空腹血糖损伤(IGF),空腹血糖7.1 mmol/L为糖尿病(DM),TC5.2 mmol/L为高胆固醇血症,LDL-C3.38 mmol/L为低密度脂蛋白胆固醇增高。    1.3  资料的汇总  资料汇集后,进行汇总分析，统计并比较不同性别、不同年龄组的各项心血管危险因素(高血压、IGF、糖尿病、高胆固醇血