Vitamin project维生素B的基本介绍

1、Vitamin BSchenna &Lisa IntroductionThere are eight vitamins B and they all have different roles in our body. All vitamin B are water soluble that means vitamin B can dissolve in water and cannot store in our bodies. Vitamin B is mainly help our body to create energy from food we eat, and aide th

2、e process of metabolizing proteins and fats.Metabolic pathwaysB12Mouth-StomachR-protein is secreted in the salivary gland and goes down to the stomach with B12.Pepsin in the stomach will be secreted to separate B12 from meatStomachB12 will bind to R-proteinParietal cell will secrete hydrogen ions to

3、 increase the acidity and intrinsic factor.Stomach-duodenum-Jejunum-ileumProtease from pancreas will remove the bond of B12 and R-proteinB12 will bind to intrinsic factor and they will travel down jejunum and ileum.By the end of ileum, B12 is absorbed by the help of intrinsic factor. Recommended Dai

4、ly AllowanceWhole grains and kale (B1)Milk and yogurt (B2)Eggs and beans (B3)Avocados and meat (B5)Sunflower seeds and carrots (B6)Barley and potatoes (B7)Salmon and beets (B9)Shellfish and pork (B12)Recommended daily allowance of vitamin B12 is 2.4 mcg(micrograms) Deficiency SymptomsFatigueSkin ras

5、hShortness of breathBad digestionPhysiology of deficiency Some people who are gluten-intolerant will produce an abnormal immune response when it breaks down gluten from wheat that triggers destruction of their intestine. When their intestine are damaged, prietal cell cannot function well that leads

6、to reduction of intrinsic factor and HCl that will lead to deficiency of vitamin B12. Physiology of deficiencyDeficiency of vitamin B12 will reduce the amount of the production of red blood cells, so oxygen cannot combine as much with red blood cells as we ususally need to provide to the body that w

7、ill make us feel tired and lack of energy. Why people have fatigue?Toxicity symptomsItchiness on different body parts and numbnessImproper heart functioning, giddiness Regular headaches Increasing the risk of getting cancerCell deathVitamin B12 can help to stimulate cell divisions, however it cannot

8、 distinguish between harmful and useful cells. And hence, vitamin B12 may increase the growth of cancer cells because its stimulation of cell division. Toxicity of vitamin BCyanocobalamin c-lactam reversibly impaired the incorporation of 5-14CH3-tetrahydrofolate and 1-14C propionic acid by intact ce

9、lls, consistent with inhibition of methionine synthase and methylmalonyl-CoA mutase. A substantial proportion of 5-14CH3-tetrahydrofolate uptake could not be suppressed by methionine and may, therefore, have occurred outside of the methionine synthase pathway. These findings are the first indication that